Principles of Contrast Enhancement in Computerized Tomography
In his early experience with computerized tomography (CT) AMBROSE (1973) observed that in travenous administration of 30 ml methyl glucamineiotha-lamate (70%) caused enhancement of X-ray attenuation in various brain tumors. Meanwhile the application of iodinated contrast media priorto are peated CT scan has become a routine method, especially in the diagnos is of intracranial tumors since most of them can be visualized better in the post contrastscan. In or der to optimize attenuation enhancement, larger doses of contrast material are used. Administration usually is carrie dout by bolus injection, by in fusion technique, or by acombination of both methods. Our own experience is based on the application of the bolustechnique using sodium diatrizoate (60%) in a dosage of 1 ml per kg body weight.
KeywordsContrast Enhancement Venous Blood Sample Normal Brain Tissue Iodine Content Cranial Compute Tomography
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