On the Endoendothelial Fibrin Layer, Fibrin(ogen) Polymerization, and Thrombosis
Two concepts are presented. One concerns the presence of fibrin in the so-called endoendothelial lining on the endothelial cells facing the vascular lumen, as well as fibrin as a constituent of associated structures, such as diaphragms of fenestrae, the stomatal diaphragms of plasmalemmal vesicles and the basement membrane. The other concept concerns the initiation of thrombosis due to an adsorption process of fibrinogen and of other plasma proteins and the polymerization of fibrinogen without thrombin participation upon the application of shearing forces.
KeywordsPermeability Torque Polysaccharide Luminal Thrombin
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