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Developmental Biology and Pathology pp 105–120Cite as

Uterine Secretion Protein Patterns Under Hormonal Influences

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Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 62))

Abstract

It is a fundamental endocrine phenomenon that the ovarian hormones control the oviducal and uterine functions, the significance of which becomes evident in sperm capacitation, egg fertilization, cleavage, blastocyst development, and implantation. Throughout all stages of pregnancy, embryologists and endocrinologists have influenced experimentally mammalian pregnancy by ovariectomy, and have tried by various means and with different success to replace the lacking ovarian hormones. This has been a useful tool in demonstrating the essential role of estrogens and progesterone to maintain pregnancy, as well as to show roughly the quantitation of these essential steroids on a daily or even shorter basis. Naturally, this experimental approach turned out insufficently in the attempt to obtain the actual steroid levels within the maternal blood stream during pregnancy. However, the recent development of highly sophisticated methods by using radioimmune reactions has presented much information about the physiological hormone concentrations, turnover rates, binding at the target tissue’s cellular level, and elimination from tissues and the circulation.

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Authors
  1. H. M. Beier
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Editors and Affiliations

  1. Abteilung für Pathologie, Medizinische Hochschule Lübeck, Ratzeburger Allee 160, D-2400, Lübeck, Germany

    A. Gropp (Professor Dr.) (Professor Dr.)

  2. Department of Obstetrics and Gynecology, San Diego School of Medicine, La Jolla, CA, 92308, USA

    K. Benirschke (Professor Dr.) (Professor Dr.)

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© 1976 Springer-Verlag Berlin-Heidelberg

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Beier, H.M. (1976). Uterine Secretion Protein Patterns Under Hormonal Influences. In: Gropp, A., Benirschke, K. (eds) Developmental Biology and Pathology. Current Topics in Pathology, vol 62. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66458-8_8

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  • DOI: https://doi.org/10.1007/978-3-642-66458-8_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-66460-1

  • Online ISBN: 978-3-642-66458-8

  • eBook Packages: Springer Book Archive

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