Abstract
The progressive events taking place in the nucleus from the intact germinal vesicle stage to the second meiotic metaphase will be referred to here as oocyte maturation. This maturation, which is under the influence of gonadotrophins, is a prerequisite for rendering an oocyte fertilizable by a spermatozoon. Whether the subsequent cleavage and development is normal relies heavily on the existence of cortical granules and on the secretion of their contents at the moment of sperm attachment. The development of a defense mechanism to avoid polyspermy is initiated during the oocyte growth phase. Even though in most cases the spermatozoon is incorporated entirely during its penetration process, the question remains if in addition to the nucleus, other organelles entering with it remain physiologically active. In this regard, the mitochondria with their known mechanism for self-replication, and centrioles, which in somatic cells duplicate themselves, are of particular interest. The developmental changes of some organelles will be discussed under normal and certain pathologic conditions. The more recent findings of virus-like “A” particles will also be presented.
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References
Andersen, H.K., Jeppesen, T.: Virus-like particles in guinea pig oogonia and oocytes. J. nat. Cancer Inst. 49, 1403–1410 (1972).
Anderson, E.: The localization of acid phosphatase and the uptake of horseradish peroxidase in the oocyte and follicle cells of mammals (eds. J.D. Biggers and A. W. Schuetz). Oogenesis, Ch. 5, 87–117 (1970).
Anderson, W.A.: Structure and fate of the parental mitochondrion during early embryogenesis of Paracentrotus lividus. J. Ultrastruct. Res. 34, 211–321 (1968).
Austin, C.R.: Cortical granules in hamster eggs. Exp. Cell Res. 10, 533 (1956).
Austin, C.R.: The Mammalian Egg. Oxford: Blackwell 1961.
Bernhard, W.: The detection and study of tumor viruses with the electron microscope. Cancer Res. 20, 712–727 (1960).
Biczysko, W., Pienkowski, M., Solter, D., Koprowski, H.: Virus particles in early mouse embryos. J. nat. Cancer Inst. 51, 1041–1050 (1973).
Calarco, P.G.: The kinetochore in oocyte maturation (eds. J.D. Biggers and A. W. Schuetz). Oogenesis, Ch. 5, 65–89 (1972).
Calarco, P.G., Donahue, R.P., Szöllösi, D.: Germinal vesicle breakdown in the mouse oocyte. J. Cell Sci. 10, 369–385 (1972).
Calarco, P.G., Szöllösi, D.: Intracisternal A particles in ova and preimplantation stages of the the mouse. Nature (New Biol.) 243, 91–93 (1973).
Chase, D.G., Piko, L.: Expression of A-and C-type particles in early mouse embryos. J. nat. Cancer Inst. 51, 1871–1975 (1973).
Dawid, I.B., Blackler, A. W.: Maternal and cytoplasmic heritance of mitochondrial DNA in Xenopus. Develop. Biol. 29, 152–161 (1972).
Donahue, R.P.: Maturation of the mouse oocyte in vitro. I Sequence and timing of nuclear progression. J. exp. Zool. 169, 237 (1968).
Enders, A.C., Schlafke, S.J.: The fine structure of the blastocyst: some comparative studies. In: Preimplantation stages of pregnancy (eds. G.E. W. Wolstenholme and M. O’Connor). Ciba Foundation Symposium. Boston: Little, Brown 1965.
Fawcett, D. W.:The anatomy of the mammalian spermatozoon With particular reference to the guinea pig. Z. Zellforsch. 67, 279–296 (1965).
Flechon, E.: Nature glycoprotéique des granules corticaux de l’oeuf de lapine. Mise en evidence par l’utilisation comparée de techniques cytochimiques ultrastructurales. J. Microscopie 9, 221–242 (1970).
Flechon, J.E., Huneau, D., Solari, A., Thibault, C.: Réaction corticale et blocage de la polyspermie dans l’oeuf de lapine. Ann. Biol. anim. Biochim. Biophys. 15, 9–18 (1975).
Franklin, L.E., Fussell, E.N.: Evolution of the apical body in golden hamster spermatids with some reference to primates. Biol. Reprod. 7, 194–206 (1972).
Gulyas, B.J.: Cortical granules in artificially activated (Parthenogenetic) rabbit eggs. J. Anat. 140, 577–582 (1974).
Gwatkin, R.B.L., Williams, D. T., Hartmann, F.J., Kniazuk, M.: The zona reaction of hamster and mouse eggs: production in vitro by a trypsin-like protease from cortical granules. J. Reprod. Fertil. 32, 259–266 (1973).
Kuff, E.L., Lueders, K.K., Ozer, W.L., Wivel, N.A.: Some structural and antigenic properties of intracisternal A particles occurring in mouse tumors. P.N.A.S. 69, 218–222 (1972).
Longo, F.J., Schuel, H.: An ultrastructural examination of polyspermy induced by soybean trypsin inhibitor in the sea urchin Arbacia punctulata. Develp. Biol. 34, 187–199 (1973).
Perotti, M.E.: The mitochondrial derivative of the spermatozoon of Drosophila before and after fertilization. J. Ultrastruct. Res. 44, 181–198 (1973).
Pickett-Heaps, F.D.: The autonomy of the centriole: fact or fallacy? Cytobios 3, 205–214 (1971).
Szöllösi, D.: Cortical granules: a general feature of mammalian eggs? J. Reprod. Fertil. 4, 223 (1962).
Szöllösi, D.: The fate of sperm middle-piece mitochondria in the rat egg. J. exp. Zool. 159, 367–377 (1965).
Szöllösi, D.: Development of cortical granules and the cortical reaction in rat and hamster eggs. Anat. Rec. 159, 431–446 (1967).
Szöllösi, D.: Changes of some cell organelles during oogenesis in mammals (eds. D.J. Biggers and A. Schuetz). Oogenesis, Ch. 5, 47–86 (1970).
Szöllösi, D.: Cortical cytoplasmic filaments of cleaving eggs: A structural element corresponding to the contractile ring. J. Cell Biol. 44, 192–209 (1970).
Szöllösi, D.: Morphological changes in mouse eggs due to aging in the fallopian tube. J. Anat. 130, 209–225 (1971).
Szöllösi, D.: The spindle structure in mammalian eggs: the effect of aging. Proceedings of the Symposium sponsored by INSERM, DGRST, OMS (eds. A. Boue and C. Thibault) 1973a.
Szöllösi, D.: The fate of the proximal centriole of porcine sperm penetrating an egg. J. Cell Biol. 59, 342a (1973b).
Szöllösi, D.: Mammalian eggs aging in the fallopian tubes. Basel: Karger A.G. 1974.
Szöllösi, D., Calarco, P.G., Donahue, R.P.: Absence of centrioles in the first and second meiotic spindles of mouse oocytes. J. Cell Sci. 11, 521–541 (1972a).
Szöllösi, D., Calarco, P.G., Donahue, R.P.: The nuclear envelope: its breakdown and fate in mammalian oogonia and oocytes. Anat. Rec. 174, 325–340 (1972b).
Szöllösi, D., Hunter, R.H.F.: Ultrastructural aspects of fertilization in the domestic pig: sperm penetration and pronucleus formation. J. Anat. 116, 181–206 (1973).
Szöllösi, D., Hans Ris, P.D.: Observations of sperm penetration in the rat. J. Biophys. Biochem. Cytol. 10, 275–283 (1961).
Vacquier, V.D., Tegner, M.J., Epel, D.: Protease activity establishes the block against polyspermy in sea urchin eggs. Nature (Lond.) 240, 352–353 (1972).
Woolley, D.M., Fawcett, D. W.: The degeneration and disappearance of the centrioles during the development of the rat spermatozoon. Anat. Rec. 177, 289–302 (1973).
Yanagimachi, R., Chang, M.C.: Fertilizable life of golden hamster ova and their morphological changes at the time of losing fertilizability. J. exp. Zool. 148, 185–203 (1961).
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Szöllösi, D. (1976). Oocyte Maturation and Paternal Contribution to the Embryo in Mammals. In: Gropp, A., Benirschke, K. (eds) Developmental Biology and Pathology. Current Topics in Pathology, vol 62. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66458-8_2
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DOI: https://doi.org/10.1007/978-3-642-66458-8_2
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