Abstract
Irradiation of a cell not only leads to the loss of reproductive integrity as measured by colony forming ability but also causes disturbances in many metabolic events and cell progression. Genetically determined repair and recovery processes may act on many of these parameters. It is, of course, not possible to measure all possible alterations, but the study of some key metabolic processes might help to understand the chain of events ultimately leading to cell death and the involvement of repair and recovery.
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Bos, R.C., van den, Retél, J., Planta, R.J.: The size and location of the ribosomal RNA segments in ribosomal precursor RNA of yeast. Biochim. Biophys. Acta (Amst.) 232, 494–508 (1971)
Brendel, M., Fäth, W.W., Toper, R.: DNA-specific labelling by deoxyribonucleoside 5’-monophosphates in Saccharomyces cerevisiae. In: Radiation and Cellular Control Processes (Kiefer, J., ed.). Berlin-Heidelberg-New York: Springer, 1976, pp. 35–40
Game, J.C., Cox, B.X.: Allelism tests of mutants affecting sensitivity to radiation in yeast and a proposed nomenclature. Mutation Res. 12, 328–331 (1971)
Gocke, E., Kiefer, J.: Inducible enzyme synthesis in irradiated yeast. In: Radiation and Cellular Control Processes (Kiefer, J., ed.). Berlin-Heidelberg-New York: Springer, 1976, pp. 59–67
Grivell, A.R., Jackson, J.F.: Thymidine kinase: evidence for its absence in Neurospora crossa and some other microorganisms, and the relevance of this to the specific labelling of deoxyribonucleic acid. J. Gen. Microbiol. 54, 307–317 (1968)
Gudas, L.J., Pardee, A.B.: Model for regulation of Escherichia coli DNA repair functions. Proc. Nat. Acad. Sci. USA 72, 2330–2334 (1975)
Hackett, P.B., Sauerbier, W.: Radiological mapping of the ribosomal RNA transcription unit in E. coli. Nature (Lond.) 251, 639–641 (1974)
Hatchard, C.G., Parker, C.A.: A new sensitive chemical actinometer. II. Potassium ferrioxalate as a standard chemical actinometer. Proc. Roy. Soc. A 235, 518–536 (1956)
Kiefer, J.: Metabolic changes in Saccharomyces cerevisiae after UV-and X-irradiation. Proc. 3rd Spec. Symp. on Yeast (Suomalainen, H., Waller, C, eds.). I, 46 (1973)
Kiefer, J.: Energy metabolism in yeast cells after UV- and X-irradiation. Int. J. Radiat. Biol. 26, 167–179 (1974)
Koch, H.: Synthese der ribosomalen Ribonukleinsäure nach Bestrahlung in stationären Hefezellen unterschiedlicher Empfindlichkeit. Ph.D. Thesis, University of Giessen, 1975
Koch, H., Kiefer, J.: RNA synthesis in irradiated diploid yeast at 50% survival level. Int. J. Radiat. Biol. 21, 223–234 (1972)
Laske, B.: Untersuchungen zur Proteinsynthese in bestrahlten Hefen. Diploma Thesis, University of Giessen, 1974
Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randall, R.J.: Protein measurement with the folin phenol reagent. J. Biol. Chem. 193, 265–275 (1951)
Resnick, M.A., Setlow, J.K.: Repair of pyrimidine dimer damage induced in yeast by ultraviolet light. J. Bacteriol. 109, 979–989 (1972)
Segdwick, S.G.: Ultraviolet inducible protein associated with error prone repair in E. coli B. Nature (Lond.) 255, 349–350 (1975)
Swenson, P.A.: Physiological response of Escherichia coli to far-ultraviolet radiation. Photochem. Photobiol. Revs., in press
Udem, S.A., Warner, J.R.: Ribosomal RNA synthesis in Saccharomyces cerevisiae. J. Molec. Biol. 65, 227–242 (1972)
Unrau, P., Wheatcroft, R., Cox, B.S.: Methods for the assay of UV light induced pyrimidine dimers in Saccharomyces cerevisiae. Biochim. Biophys. Acta (Amst.) 269, 311–321 (1972)
Wickerham, L.J.: Taxonomy of yeasts. USDA Tech. Bull. 1029, p. 1–56 (1951)
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Kiefer, J., Koch, H., Laske, B., Waller, H. (1976). Metabolism of Yeast Cells after UV-and X-Ray Irradiation. In: Kiefer, J. (eds) Radiation and Cellular Control Processes. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66455-7_7
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DOI: https://doi.org/10.1007/978-3-642-66455-7_7
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