Abstract
In 1972, Harris reported that co-cultivation of a lethally irradiated Chinese hamster population with another that was unirradiated, led to the formation of hybrid clones containing functional marker alleles from irradiated nuclei. As part of a study of the radiobiology of somatic cell hybridization, we have examined further aspects of this phenomenon.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Chadwick, K.H., Leenhouts, H.P.: The repair of potentially lethal damage: an alternative approach. Radiat. Environ. Biophys. 11, 319–325 (1975)
Dulbecco, R., Vogt, M.: Plaque formation and isolation of pure lines with poliomyelitis viruses. J. Exp. Med. 99, 167–182 (1954)
Harris, M.: Effect of x-irradiation of one partner on hybrid frequency in fusions between Chinese hamster cells. J. Cell Physiol. 80, 119–128 (1972)
Littlefield, J.W.: The inosinic acid pyrophosphorylase activity of mouse fibroblasts partially resistant to 8 azaguanine. Proc. Nat. Acad. Sci. USA 50, 568–573 (1963)
Pontecorvo, G.: Induction of directional chromosome elimination in somatic cell hybrids. Nature (Lond.) 230, 367–369 (1971)
Pontecorvo, G.: Induced chromosome elimination in hybrid cells. In: Somatic Cell Hybridization (Davidson, R.L., de la Cruz, F., eds.). New York: Raven Press, 1974, pp. 65–68
Sperling, K., Rao, P.N.: The phenomenon of premature chromosome condensation: its relevance to basic and applied research. Humangenetik 23, 235–258 (1974)
Waldren, C.A., Johnson, R.T.: Analysis of interphase chromosome damage by means of premature chromosome condensation after x- and ultraviolet-irradiation. Proc. Nat. Acad. Sci. USA 71, 1137–1141 (1974)
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1976 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Kinsella, A.R., Smith, P.J., Boyle, J.M. (1976). Recovery from Radiation Damage Mediated by Somatic Cell Hybridisation. In: Kiefer, J. (eds) Radiation and Cellular Control Processes. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66455-7_22
Download citation
DOI: https://doi.org/10.1007/978-3-642-66455-7_22
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-66457-1
Online ISBN: 978-3-642-66455-7
eBook Packages: Springer Book Archive