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Kinetics of Antagonist Action

  • Chapter
Histamine II and Anti-Histaminics

Abstract

In Chapter IV.A of this volume we deal in more detail with the kinetics of the interaction of antihistaminics with the so-called H1 receptors for histamine. In the present subchapter we will study general aspects of that interaction, having in view the possibility of developing a general theory that might embody the interaction of agonists (including cholinomimetics) and antagonists with receptors, from a thermodynamic standpoint.

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Authors
  1. Mauricio Rocha e Silva
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Editors and Affiliations

  1. Department of Pharmacology, Faculty of Medicine of Ribeirão Preto, University of São Paulo, 14.100, Ribeirão Preto, S.P., Brazil

    Mauricio Rocha e Silva

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Rocha e Silva, M. (1978). Kinetics of Antagonist Action. In: Rocha e Silva, M. (eds) Histamine II and Anti-Histaminics. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology, vol 18 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66445-8_7

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  • DOI: https://doi.org/10.1007/978-3-642-66445-8_7

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  • Print ISBN: 978-3-642-66447-2

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