Effect of Sodium Nitroprusside, Temperature, and Calcium Withdrawal on the Relaxation Speed of Vascular Smooth Muscle
Sodium nitroprusside (NP; Nipruss, Nipride) is a powerful inhibitor of excitation-contraction coupling in vascular smooth muscle. Our older findings on its cellular mode of action were published elsewhere (5). Recently, we have begun to study the relaxation process of slowly relaxing arterial strips by measuring the effect of NP and other measures on the speed of relaxation. This is a first and preliminary report from current work, and some of the findings and conclusions in this presentation might be liable to alterations with advancing work.
KeywordsAdenosine Caffeine Norepinephrine Adrenaline Acetylcholine
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