Membrane Basis of Vascular Regulation

  • G. Siegel
  • G. Niesert
  • R. Ehehalt
  • O. Bertsche


In recent years physiologists who work on smooth muscle have concentrated on two basic questions: (1) Is some kind of electrical depolarization of the cell membrane a prerequisite for an increase in mechanical tension under normal conditions, and (2) What are the causes of autorhythmicity in smooth muscle? Both research fields, excitation-contraction coupling and the origin of rhythmic spontaneous activity, leave many questions open, especially in the field of vascular smooth muscle. If the question of an electromechanical coupling in vascular smooth muscle can be positively answered, then a related question becomes how the membrane potential is influenced and regulated.


Membrane Potential Vascular Smooth Muscle Electromechanical Coupling Krebs Solution Pump Current 
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© Springer-Verlag Berlin Heidelberg 1976

Authors and Affiliations

  • G. Siegel
  • G. Niesert
  • R. Ehehalt
  • O. Bertsche

There are no affiliations available

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