Abstract
Injections of polyunsaturated phosphatidylcholine solution in sodium desoxycholate are known to alter the activity of a number of enzymes of the aortic wall, that are involved in the metabolism of phospholipids, triglycerides and cholesteryl esters and to reduce aortic atherosclerosis.
This overview of investigations concerned with the aortic enzymes demonstrates the types of reactions in the metabolism of cholesterol and cholesteryl esters in the arterial wall, characterizes the enzymes (reaction rates, pH optima), and reveals the importance of saturation and chain length of the acyl moieties in the substrate molecules. The acyl exchange in cholesteryl esters as mediated by polyunsaturated phosphatidylcholine is discussed with regard to its importance for the degradation of the cholesteryl esters in the arterial wall.
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References
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© 1976 Springer-Verlag Berlin Heidelberg
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Patelski, J. (1976). Arterial Metabolism of Cholesteryl Esters. In: Peeters, H. (eds) Phosphatidylcholine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66424-3_15
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DOI: https://doi.org/10.1007/978-3-642-66424-3_15
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-66426-7
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