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Dissociation of the Androgenic and Other Hormonal Activities from the Protein Anabolic Effects of Steroids

  • Chapter
Anabolic-Androgenic Steroids

Abstract

Much research effort has been expended over the last two decades in laboratories throughout the world in search of a molecule that possesses all the anabolic properties of the male hormone, testosterone, but does not elicit responses generally characterized as virilizing. These efforts have been justified on the premise that a “pure” anabolic agent would be expected to find many more clinical applications and be more generally accepted by the medical specialists than testosterone and its derivatives, particularly for longterm uses associated with debilitating disease states, slow rate of healing of hard or soft tissue, and, in general, for conditions where conservation of the body’s quantity of protein or replenishment of depleted protein states were sought. The clinical preference for an anabolic over an androgenic agent in the above-listed uses would derive from the view that the androgenic or masculinizing actions of the latter would be unwanted or considered as side-effects particularly for children and women.

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Authors
  1. G. O. Potts
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  2. A. Arnold
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  3. A. L. Beyler
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Editors and Affiliations

  1. Experimental Endocrinology, The University of Alabama in Birmingham, Medical Center, 1919 Seventh Avenue South, Birmingham, AL, 35294, USA

    Charles D. Kochakian Ph.D. (Director and Professor) (Director and Professor)

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Potts, G.O., Arnold, A., Beyler, A.L. (1976). Dissociation of the Androgenic and Other Hormonal Activities from the Protein Anabolic Effects of Steroids. In: Kochakian, C.D. (eds) Anabolic-Androgenic Steroids. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology, vol 43. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66353-6_11

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  • DOI: https://doi.org/10.1007/978-3-642-66353-6_11

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