The Optic Pathway of the Frog: Nuclear Organization and Connections

  • F. Scalia


The information for this Chapter was drawn largely from recent normal and experimental morphological studies on the adult visual system of Rana pipiens, Rana catesbeiana, Rana temporaria, and Rana esculenta. However, a great debt is owed to a number of previous investigators, such as Bellonci (1888), Wlassak (1893), Ramon (1894), Gaupp (1899), Rothig (1923, 1926), Herrick (1925) and Frontera (1952), who have provided a background of fundamental perspectives on the organization of the frog’s brain. Recent applications of contemporary experimental morphological techniques to studies on the tadpole have also provided information on the development of the visual system. For the most part, the data organized in this chapter has been published elsewhere, but certain gaps will be filled from unpublished observations or from experiments in progress.


Lateral Geniculate Nucleus Optic Tract Optic Tectum Nuclear Organization Retinal Projection 
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  1. Bellonci, J.: Über die centrale Endigung des Nervus opticus bei den Vertebraten. Z. wiss. Zool. 47, 1–46 (1888).Google Scholar
  2. Currie, J.R.: Some observations on the development of the visual system in the frog, Rana pipiens. Doctoral dissertation. Washington Univ. St. Louis, Mo. (1974).Google Scholar
  3. Currie, J.R., Cowan, W.M.: Evidence for the late development of the uncrossed retinothalamic projections in the frog, Rana pipiens. Brain Res. 71, 133–139 (1974).PubMedCrossRefGoogle Scholar
  4. Frontera, J.G.: A study of the anuran diencephalon. J. comp. Neurol. 96, 1–69 (1952).PubMedCrossRefGoogle Scholar
  5. Gaupp, E.: Anatomie des Frosches (Ecker and Wiederschein eds.). Braunschweig: Vieweg 1899.Google Scholar
  6. Gaze, R.M., Keating, M.J., Chung, S.H.: The evolution of the retinotectal map during development in Xenopus. Proc. roy. Soc. B 185, 301–330 (1974).CrossRefGoogle Scholar
  7. Gruberg, E.R., Ambros, V.R.: A forebrain visual projection in the frog (Rana pipiens). Exp. Neurol. 44, 187–197 (1974).PubMedCrossRefGoogle Scholar
  8. Herrick, C.J.: The amphibian forebrain. III. The optic tracts and centers of Amblystoma and the frog. J. comp. Neurol. 39, 433–489 (1925).CrossRefGoogle Scholar
  9. Hollyfield, J.G.: Differential addition of cells to the retina in Rana pipiens tadpoles. Develop. Biol. 18, 163–179 (1968).PubMedCrossRefGoogle Scholar
  10. Jacobson, M.: The representation of the retina on the optic tectum of the frog. Correlation between retinotectal magnification factor and retinal ganglion cell count. Quart. J. exp. Physiol. 47, 170–178 (1962).PubMedGoogle Scholar
  11. Kappers, C.U. Ariens, Huber, G.C., Crosby, E.C.: The Comparative Anatomy of the Nervous System of Vertebrates, Including Man. Vol. II. New York: Macmillan 1936.Google Scholar
  12. Kicliter, E.: An anatomical connection between the anterior thalamus and the telencephalon in the frog. Proc. Soc. Neurosci. Third Ann. Meet. 410 (1973).Google Scholar
  13. Knapp, H., Scalia, F., Riss, W.: The optic tracts of Rana pipiens. Acta neurol. scand. 41, 325–355 (1965).CrossRefGoogle Scholar
  14. Kollros, J.J.: The development of the optic lobes in the frog. J. exp. Zool. 123, 153–187 (1953).CrossRefGoogle Scholar
  15. Larsell, O.: The nucleus isthmi of the frog. J. comp. Neurol. 36, 309–322 (1924).CrossRefGoogle Scholar
  16. Larsell, O.: The differentiation of the peripheral and central acoustic apparatus in the frog. J. comp. Neurol. 60, 473–527 (1934).CrossRefGoogle Scholar
  17. Lázár, G.: Efferent pathways of the optic tectum in the frog. Acta biol. Acad. Sci. hung. 20, 171–183 (1969).PubMedGoogle Scholar
  18. Lázár, G.: The projection of the retinal quadrants on the optic centers in the frog. A terminal degeneration study. Acta morph. Acad. Sci. hung. 19, 325–334 (1971).Google Scholar
  19. Lázár, G.: The role of the accessory optic system in the optokinetic nystagmus of the frog. Brain, Behav. Evol. 5, 443–460 (1973).Google Scholar
  20. Lázár, G., Székely, G.: Golgi studies on the optic center of the frog. J. Hirnforsch. 9, 329–344 (1967).PubMedGoogle Scholar
  21. Lázár, G., Székely, G.: Distribution of optic terminals in the different optic centers in the frog. Brain Res. 16, 1–14 (1969).PubMedCrossRefGoogle Scholar
  22. Potter, H.D.: Mesencephalic auditory region of the bullfrog. J. Neurophysiol. 28, 1132–1154 (1965).PubMedGoogle Scholar
  23. Potter, H.D.: Structural characteristics of cell and fiber populations in the optic tectum of the frog (Rana catesbeiana). J. comp. Neurol. 136, 203–232 (1969).PubMedCrossRefGoogle Scholar
  24. Potter, H.D.: Terminal arborizations of retinotectal axons in the bullfrog. J. comp. Neurol. 144, 269–283 (1972).PubMedCrossRefGoogle Scholar
  25. Ramon, P.: Investigaciones micrograficas en el encephalo de los batracecos y reptiles, cuerpos geniculados y tuberculo cuadrigeninos de los mamiferos. Fac. Med. Zaragoza (1894).Google Scholar
  26. Riss, W., Ingle, D.: Report of a conference on the anuran visual system. Brain, Behav. Evol. 8, 321–326 (1973).CrossRefGoogle Scholar
  27. Rothig, P.: Beiträge zum Studium des Centralnervensystems der Wirbeltiere. 8. Über des Zwischenhirn der Amphibien. Arch. mikr. Anat. 98, 616–645 (1923).Google Scholar
  28. Rothig, P.: Über die Faserzüge im Vorder- und Zwischenhirn der Anuren. Jb. Morph. mikr. Anat. Abt. 2, Z. mikr.-anat. Forsch. 5, 23–58 (1926).Google Scholar
  29. Rubinson, K.: Projections of the tectum opticum of the frog. Brain, Behav. Evol. 1, 529–561 (1968).CrossRefGoogle Scholar
  30. Rubinson, K., Skiles, M.: Efferent projections from the superior olivary nucleus in Rana catesbeiana. Anat. Rec. 175, 431 (1973).Google Scholar
  31. Scalia, F.: Autoradiographic demonstration of optic nerve fibers in the stratum zonale of the frog’s tectum. Brain Res. 58, 484–488 (1973).PubMedCrossRefGoogle Scholar
  32. Scalia, F., Colman, D.R.: Aspects of the central projection of the optic nerve in the frog as revealed by anterograde migration of horseradish peroxidase. Brain Res. 79, 496–504 (1974).PubMedCrossRefGoogle Scholar
  33. Scalia, F., Colman, D.R.: Identification of telencephalic-afferent thalamic nuclei associated with the visual system of the frog. Neurosci. Abst. 1, 46 (1975).Google Scholar
  34. Scalia, F., Fite, K.: A retinotopic analysis of the central connections of the optic nerve in the frog. J. comp. Neurol. 158, 455–478 (1974).PubMedCrossRefGoogle Scholar
  35. Scalia, F., Gregory, K.: Retinofugal projections in the frog: location of the postsynaptic neurons, Brain, Behav. Evol. 3, 16–29 (1970).CrossRefGoogle Scholar
  36. Scalia, F., Knapp, H., Halpern, M., Riss, W.: New observations on the retinal projection in the frog Brain, Behav. Evol. 1, 324–353 (1968).CrossRefGoogle Scholar
  37. Scott, T.M.: The development of the retino-tectal projection in Xenopus laevis: an autoradiographic and degeneration study. J. Embryol. exp. Morph. 31, 409–414 (1974).PubMedGoogle Scholar
  38. Straznicky, K., Gaze, R.M.: The growth of the retina in Xenopus laevis: an autoradiographic study. J. Embryol. exp. Morph. 26, 67–79 (1971).PubMedGoogle Scholar
  39. Straznicky, R., Gaze, R.M.: The development of the tectum in Xenopus laevis: an autoradiographic study. J. Embryol. exp. Morph. 28, 87–115 (1972).PubMedGoogle Scholar
  40. Székely, G.: The mesencephalic and diencephalic optic centers in the frog. Vision Res. II (Suppl. 3), 269–279 (1971).CrossRefGoogle Scholar
  41. Székely, G., Setalo, G., Lázár, G.: Fine structure of the frog’s optic tectum: optic fiber termination layers. J. Hirnforsch. 14, 189–225 (1973).PubMedGoogle Scholar
  42. Trachtenberg, M.C., Ingle, D.: Thalamo-tectal projections in the frog. Brain Res. 79, 419–430 (1974).PubMedCrossRefGoogle Scholar
  43. Wlassak, R.: Die optischen Leitungsbahnen des Frosches. Arch. Anat. Physiol., Physiol. Abt., Suppl. S, 1–28 (1893).Google Scholar

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© Springer-Verlag Berlin · Heidelberg 1976

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  • F. Scalia

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