Skip to main content
SpringerLink
Log in

Vesicular Stomatitis Virus: Structure and Function of Virion Components

  • Chapter
Current Topics in Microbiology and Immunology

Abstract

Vesicular stomatitis virus (VS) is an enveloped Rhabdovirus which is capable of productively infecting a multitude of hosts including many mammalian species, fish, and insects (Howatson, 1970; Bussereau, 1973). Two serotypes of VS virus have been identified: VSIndiana and VSNew Jersey (Pringle, 1975). The standard infectious virions of either serotype are rods (rhabdos = rod) of approximately 175 × 68 nm which have one hemispherical and one planar end and contain a helical nucleocapsid of approximately 30 equal turns followed by 4 or 5 diminishing coils at the rounded end (Howatson, 1970) (Fig. 1). Thus, virions appear bullet-shaped. Numerous “spikes” measuring 10 nm in length project externally from the entire surface of the viral envelope. Defective interfering (DI) particles which have the same morphology but are shorter and contain incomplete genomes are also produced at high multiplicities of infection. The viral envelope is acquired during maturation when nucleocapsids bud through pre-existing cell membranes; the site of budding varies according to the host species and can be on either the plasma membrane or the membranes of intracytoplasmic vesicles or on both (Zee et al., 1970).

Schematic representation of the vesicular stomatitis virion. Spikes (G protein) are shown attached to the planar end although there is no direct evidence that they are normally located there

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abraham, G., Rhodes, D. P., Banerjee, A. K.: The 5′-terminal structure of the methylated mRNA synthesized in vitro by vesicular stomatitis virus. Cell 51–58 (1975)

    Google Scholar 

  • Arstila, P., Halonen, P., Salmi, G.: Hemagglutinin of vesicular stomatitis virus. Archiv für die gesamte Virusforschung 27, 198–208 (1969)

    Article  PubMed  CAS  Google Scholar 

  • Arstila, P.: Two hemagglutinating components of vesicular stomatitis virus. Acta path, microbiol. scand. 80, 33–40 (1972)

    CAS  Google Scholar 

  • Arstila, P.: Small-sized haemagglutinin of vesicular stomatitis virus released spontaneously and with nonidet-P40. Acta path, microbiol. scand. 81, 27–36 (1973)

    CAS  Google Scholar 

  • Arstila, P.: Characteristics of vesicular stomatitis virus envelopes released with saponin. J. Gen. Virol. 24, 319–326 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Atkinson, P. H., Summers, D. F.: Purification and properties of HeLa cell plasma membranes. J. Biol. Chem. 246, 5162–5175 (1971)

    PubMed  CAS  Google Scholar 

  • Baltimore, D., Huang, A. S., Stampfer, M.: Ribonucleic acid synthesis of vesicular stomatitis virus, IL An RNA polymerase in the virion. Proc. Nat. Acad. Sci. U.S.A. 66, 572–576 (1970)

    Article  CAS  Google Scholar 

  • Baltimore, D.: Expression of animal virus genomes. Bact. Rev. 35, 235–241 (1971)

    PubMed  CAS  Google Scholar 

  • Banerjee, A. K., Rhodes, D P.: In vitro synthesis of RNA that contains polyadenylate by virion-associated RNA polymerase of vesicular stomatitis virus. Proc. Nat. Acad. Sci. U.S.A. 70, 3566–3570 (1973)

    Article  CAS  Google Scholar 

  • Banerjee, A. K., Moyer, S. A., Rhodes, D. P.: Studies on the in vitro adenylation of RNA by vesicular stomatitis virus. Virology 61, 547–558 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Barry, R. D., Mahy, B. W. J.: In: Negative Strand Viruses. New York: Academic Press, Inc. In press (1974)

    Google Scholar 

  • Berenholz, Y., Wagner, R. R., Moore, N. F.: In preparation (1975)

    Google Scholar 

  • Bishop, D. H. L.: Complete transcription by the transcriptase of vesicular stomatitis virus. J. Virol. 7, 486–490 (1971)

    PubMed  CAS  Google Scholar 

  • Bishop, D. H. L., Roy, P.: Kinetics of RNA synthesis by vesicular stomatitis virus particles. J. Mol. Biol. 57, 513–527 (1971a)

    Article  PubMed  CAS  Google Scholar 

  • Bishop, D. H. L., Roy, P.: Properties of the product synthesized by vesicular stomatitis virus particles. J. Mol. Biol. 58, 799–814 (1971b)

    Article  PubMed  CAS  Google Scholar 

  • Bishop, D. H. L., Roy, P.: Dissociation of vesicular stomatitis virus and relation of the virion proteins to the viral transcriptase. J. Virol. 10, 234–243 (1972)

    PubMed  CAS  Google Scholar 

  • Bishop, D. H., Emerson, S. U., Flamand, A.: Reconstitution of infectivity and transcriptase activity of homologous and heterologous viruses: vesicular stomatitis (Indiana serotype), Chandipura, vesicular stomatitis (New Jersey serotype), and Cocal viruses. J. Virol. 14, 139–144 (1974)

    PubMed  CAS  Google Scholar 

  • Both, G. W., Banerjee, A. K., Shatkin, A. J.: Methylation dependent translation of viral mRNAs in vitro. Proc. Nat. Acad. Sci. U.S.A. 72, 1189–1193 (1975a)

    Article  CAS  Google Scholar 

  • Both, G. W., Moyer, S.A., Banerjee, A. K.: Translation and identification of the mRNA species synthesized in vitro by the virion-associated RNA polymerase of vesicular stomatitis virus. Proc. Nat. Acad. Sci. U.S.A. 72, 274–278 (1975b).

    Article  CAS  Google Scholar 

  • Brown, F., Cartwright, B., Crick, J., Smale, C. J.: Infective virus substructure from vesicular stomatitis virus. J. Virol. 1, 368–373 (1967a)

    PubMed  CAS  Google Scholar 

  • Brown, F., Martin, S., Cartwright, B., Crick, J.: The ribonucleic acids of the infective and interfering components of vesicular stomatitis virus. J. Gen. Virol. 1, 479–486 (1967b)

    Article  PubMed  CAS  Google Scholar 

  • Brown, F., Smale, C. J., Horzink, M. C.: Lipid and protein organization in vesicular stomatitis and Sindbis viruses. J. Gen. Virol. 22, 455–458 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Burge, B. W., Huang, A. S.: Comparison of membrane protein glycopeptides of Sindbis virus and vesicular stomatitis virus. J. Virol. 6, 176–182 (1970)

    PubMed  CAS  Google Scholar 

  • Bussereau, F.: Vesicular stomatitis virus induced CO2 sensitivity in Drosophila melanogaster. 3. A study of different serotypes of the virus. Ann. Microbiol. (Paris) 124A, 535–554(1973)

    CAS  Google Scholar 

  • Cairns, J. E., Holloway, A. F., Cormack, D. V.: Temperature-sensitive mutants of vesicular stomatitis virus: in vitro studies of virion-associated polymerase. J. Virol. 10, 1130–1135 (1972)

    PubMed  CAS  Google Scholar 

  • Caliguiri, L. A., Tamm, I.: The role of cytoplasmic membranes in poliovirus biosynthesis. Virology 42, 100–122 (1970)

    Article  PubMed  CAS  Google Scholar 

  • Cartwright, B., Pearce, C. A.: Evidence for a host cell component in vesicular stomatitis virus. J. Gen. Virol. 2, 207–214 (1968)

    Article  PubMed  CAS  Google Scholar 

  • Cartwright, B., Smale, C. J., Brown, F.: Surface structure of vesicular stomatitis virus. J. Gen. Virol. 5, 1–10 (1969)

    Article  PubMed  CAS  Google Scholar 

  • Cartwright, B., Smale, C. J., Brown, F.: Dissection of vesicular stomatitis virus into infective ribonucleoprotein and immunizing components. J. Gen. Virol. 7, 19–32 (1970a)

    Article  PubMed  CAS  Google Scholar 

  • Cartwright, B., Talbot, P., Brown, F.: The proteins of biologically active subunits of vesicular stomatitis virus. J. Gen. Virol. 7, 267–272 (1970b)

    Article  PubMed  CAS  Google Scholar 

  • Cartwright, B., Smale, C. J., Brown, F., Hull, R.: Model for vesicular stomatitis virus. J. Virol. 10, 256–260 (1972a)

    PubMed  CAS  Google Scholar 

  • Cartwright, B., Brown, F.: Serological relationships between different strains of vesicular stomatitis virus. J. Gen. Virol. 16, 391–398 (1972b)

    Article  PubMed  CAS  Google Scholar 

  • Cartwright, B.: The distribution of virus proteins in BHK 21 cells infected with vesicular stomatitis virus (Indiana C). J. Gen. Virol. 21, 407–411 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Chamberlin, M. J.: The selectivity of transcription. Ann. Rev. Biochem. 43, 721–775 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Choppin, P. W., and Compans, R. W.: Phenotypic mixing of envelope proteins of the parainfluenza virus SV5 and vesicular stomatitis virus. Virology 5, 609–616 (1970)

    CAS  Google Scholar 

  • Cohen, G. H., Atkinson, P. H., Summers, D. F.: Interactions of vesicular stomatitis virus structural proteins with HeLa plasma membranes. Nature New Biol. 231, 121–123 (1971)

    Article  PubMed  CAS  Google Scholar 

  • Combard, A., Martinet, C., Printze-Ané, C., Friedman, A., Printz, P.: Transcription and replication of vesicular stomatitis virus: effects of temperature-sensitive mutations in complementation group IV. J. Virol. 13, 922–930 (1974)

    PubMed  CAS  Google Scholar 

  • Crick, J., Brown, F.: Interference as a measure of cross-relationships in the vesicular stomatitis group rhabdoviruses. J. Gen. Virol. 18, 79–82 (1973)

    Article  PubMed  CAS  Google Scholar 

  • David, A. E.: Assembly of the vesicular stomatitis virus envelope: Incorporation of viral polypeptides into the host plasma membrane. J. Mol. Biol. 76, 135–148 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Deutsch, V.: Non-genetic complementation of group V temperature sensitive mutants of vesicular stomatitis virus by UV-irradiated virus. J. Virol. 798–805 (1975)

    Google Scholar 

  • Dietzschold, B., Schneider, L. G., Cox, J. H.: Serological characterization of the three major proteins of vesicular stomatitis virus. J. Virol. 14, 1–7 (1974)

    PubMed  CAS  Google Scholar 

  • Duncan, I. B., Pringle, C. R.: Preliminary physiological characterization of temperature-sensitive mutants of vesicular stomatitis virus. J. Virol. 8, 56–61 (1971)

    PubMed  Google Scholar 

  • Ehrenfeld, E., Summers, D. F.: Adenylate-rich sequences in vesicular stomatitis virus messenger ribonucleic acid. J. Virol. 10, 683–688 (1972)

    PubMed  CAS  Google Scholar 

  • Ehrenfeld, E.: Polyadenylation of vesicular stomatitis virus mRNA. J. Virol. 13, 1055–1060(1974)

    PubMed  CAS  Google Scholar 

  • Emerson, S. U., Wagner, R. R.: Dissociation and reconstitution of the transcriptase and template activities of vesicular stomatitis B and T virions. J. Virol. 10, 297–309 (1972)

    PubMed  CAS  Google Scholar 

  • Emerson, S. U., Wagner, R. R.: L protein requirement for in vitro RNA synthesis by vesicular stomatitis virus. J. Virol. 12, 1325–1335 (1973)

    PubMed  CAS  Google Scholar 

  • Emerson, S. U., Yu, Y. H.: Both NS and L proteins are required for in vitro RNA synthesis by vesicular stomatitis virus. J. Virol. 15, 1348–1356 (1975)

    PubMed  CAS  Google Scholar 

  • Etchison, J. R., Holland, J. J.: Carbohydrate composition of the membrane glycoprotein of vesicular stomatitis virus. Virology 60, 217–229 (1974a)

    Article  PubMed  CAS  Google Scholar 

  • Etchison, J. R., Holland, J. J.: Carbohydrate composition of the membrane glycoprotein of vesicular stomatitis virus grown in four mammalian cell lines. Proc. Nat. Acad. Sci. U.S.A. 71, 4011–4014 (1974b)

    Article  CAS  Google Scholar 

  • Flamand, A.: Etude genetique du virus de la stomatite vesiculaire: classement de mutants thermosensibles spontanes en groupes de complementation. J. Gen. Virol. 8, 187–195 (1970)

    Article  PubMed  CAS  Google Scholar 

  • Flamand, A., Bishop, D. H. L.: Primary in vivo transcription of vesicular stomatitis virus and temperature-sensitive mutants of five vesicular stomatitis virus complementation groups. J. Virol. 12, 1238–1252 (1973)

    PubMed  CAS  Google Scholar 

  • Follet, E. A., Pringle, CR., Wunner, W. H., Skehel, J. J.: Virus replication in enucleate cells: vesicular stomatitis virus and influenza virus. J. Virol. 13, 394–399 (1974)

    Google Scholar 

  • Galet, H., Prevec, L.: Polyadenylate synthesis by extracts from L cells infected with vesicular stomatitis virus. Nature, N. B. 243, 200–202 (1973)

    CAS  Google Scholar 

  • Grubman, M. J., Ehrenfeld, E., Summers, D. F.: In vitro synthesis of proteins by membrane-bound polyribosomes from vesicular stomatitis virus-infected HeLa cells. J. Virol. 14, 560–571 (1974)

    PubMed  CAS  Google Scholar 

  • Hecht, T. T., Summers, D. F.: Effect of vesicular stomatitis virus infection on the histocompatibility antigen of L cells. J. Virol. 10, 578–585 (1972)

    PubMed  CAS  Google Scholar 

  • Heine, J. W., Schnaitman, C. A.: Fusion of vesicular stomatitis with the cytoplasmic membrane of L cells. J. Virol. 3, 619–622 (1969)

    PubMed  CAS  Google Scholar 

  • Heine, J. W., Schnaitman, C. A.: Entry of vesicular stomatitis virus into L cells. J. Virol. 8, 786–795 (1971)

    PubMed  CAS  Google Scholar 

  • Holland, J. J., Doyle, M., Perrault, J., Kingsbury, D., Etchison, J.: Proteinase activity in purified animal viruses. Biochem. Biophys. Res. Comm. 46, 634–639 (1972)

    Article  PubMed  CAS  Google Scholar 

  • Howatson, A. F.: Vesicular stomatitis and related viruses. Adv. Virus Research 16, 196–256 (1970)

    Google Scholar 

  • Huang, A. S., Wagner, R. R.: Defective T particles of vesicular stomatitis virus. II. Biologic role in homologous interference. Virology 30, 173–181 (1966)

    Article  PubMed  CAS  Google Scholar 

  • Huang, A. S., Wagner, R. R.: Comparative sedimentation coefficients of RNA extracted from plaque-forming and defective particles of vesicular stomatitis virus. J. Mol. Biol. 22, 381–384 (1966)

    Article  PubMed  CAS  Google Scholar 

  • Huang, A. S., Chou, J. V., Martin, R. G.; DNA infectivity and the induction of host DNA synthesis with temperature sensitive mutants of SV40. J. Virol. 15, 145160 (1975), D., Stampfer, M.: Ribonucleic acid synthesis of vesicular stomatitis virus III. Multiple complementary messenger RNA molecules. Virology 42, 946–957 (1970)

    Article  PubMed  CAS  Google Scholar 

  • Huang, A. S., Manders, E. K.: Ribonucleic acid synthesis of vesicular stomatitis virus. IV. Transcription by standard virus in the presence of defective interfering particles. J. Virol. 9, 909–916 (1972)

    PubMed  CAS  Google Scholar 

  • Huang, A. S.: Defective interfering viruses. Ann. Rev. Microbiol. 27, 101–117 (1973)

    Article  CAS  Google Scholar 

  • Huang, A. S., Palma: Vesicular stomatitis virus: defectiveness and disease. In: Mechanisms of Virus Disease (eds. W. S. Robinsons and C. F. Fox), pp. 87–99. Menlo Park, Calif.: W. A. Benjamin, Inc., 1974

    Google Scholar 

  • Hunt, D. M., Wagner, R. R.: Location of the transcription defect in group I temperature sensitive mutants of vesicular stomatitis virus. J. Virol. 13, 28–35 (1974)

    PubMed  CAS  Google Scholar 

  • Hunt, D. M., Emerson, S. U., Wagner, R. R.: In preparation (1975)

    Google Scholar 

  • Imblum, R. L., Wagner, R. R.: Protein kinase and phosphoproteins of vesicular stomatitis virus. J. Virol. 13, 113–124 (1974)

    PubMed  CAS  Google Scholar 

  • Imblum, R. L., Wagner, R. R.: Inhibition of viral transcriptase by immunoglobulin directed against the nucleocapsid NS protein of vesicular stomatitis virus. J. Virol. 15, 1357–1366 (1975)

    PubMed  CAS  Google Scholar 

  • Kang, C. Y., Prevec, L.: Proteins of vesicular stomatitis virus I. Polyacrylamide gel analysis of viral antigens. J. Virol. 3, 404–413 (1969)

    PubMed  CAS  Google Scholar 

  • Kang, C. Y., Prevec, L.: Proteins of vesicular stomatitis virus II. Immunological comparisons of viral antigens J. Virol. 6, 20–27 (1970)

    PubMed  CAS  Google Scholar 

  • Kang, C. Y., Prevec, L.: Proteins of vesicular stomatitis virus III. Intracellular synthesis and extracellular appearance of virus-specific proteins. Virology 46, 678–690 (1971)

    Article  PubMed  CAS  Google Scholar 

  • Kelley, J. M., Wagner, Emerson, S. U.: The glycoprotein of vesicular stomatitis virus is the antigen that gives rise to and reacts with neutralizing antibody. J. Virol. 10, 1231–1235 (1972)

    PubMed  CAS  Google Scholar 

  • Kelley, J. M., Emerson, S. U.: Cyanogen bromide peptide map analyses of the glycoprotein from vesicular stomatitis virus. In preparation (1975)

    Google Scholar 

  • Klenk, H.-D., P. W.: Glycolipid content of vesicular stomatitis virus grown in baby hamster kidney cells. J. Virol. 7, 416–417 (1971)

    PubMed  CAS  Google Scholar 

  • Lafay, F.: Envelope proteins of vesicular stomatitis virus: Effect of temperature-sensitive mutations in complementation groups III and IV. J. Virol. 14, 1220–1228 (1974)

    PubMed  CAS  Google Scholar 

  • Leamnson, R. N., Reichmann, M. E.: The RNA of defective vesicular stomatitis virus particles in relation to viral cistrons. J. Mol. Biol. 85, 551–568 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Lenard, J., Compans, R. W.: The membrane structure of lipid containing viruses. Biochimica et Biophysica Acta (MR) 344, 51–94 (1974)

    CAS  Google Scholar 

  • Love, D. N.; Weiss, R.: Pseudotypes of vesicular stomatitis virus determined by exogenous and endogenous avian RNA tumor viruses. Virology 57, 271–278 (1974)

    Article  PubMed  CAS  Google Scholar 

  • McSharry, J. J., Wagner, R. R.: Lipid composition of purified vesicular stomatitis viruses. J. Virol. 7, 59–70 (1971a)

    PubMed  CAS  Google Scholar 

  • McSharry, J. J., Wagner, R. R.: Carbohydrate composition of vesicular stomatitis virus. J. Virol. 7, 412–415 (1971b)

    PubMed  CAS  Google Scholar 

  • McSharry, J. J., Compans, R. W., Choppin, P. W.: Proteins of vesicular stomatitis virus and of phenotypically mixed vesicular stomatitis virus — simian virus 5 virions. J. Virol. 8, 722–729 (1971)

    PubMed  CAS  Google Scholar 

  • Moore, N. F., Kelley, J. M., Wagner, R. R.: Envelope proteins of vesicular stomatitis virions: Accessibility to iodination. Virology 61, 292–296 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Mori, H., Howatson, A. F.: In vitro transcriptase activity of vesicular stomatitis virus B and T particles: Analysis of product. Intervirology 1, 168–175 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Moore, N. F., Wagner, R. R., Berenholz, Y.: In preparation (1975)

    Google Scholar 

  • Morrison, T., Stampfer, M., Baltimore, D., Lodish, H. F.: Translation of vesicular Stomatitis messenger RNA by extracts from mammalian and plant cells. J. Virol. 13, 67–72(1974)

    Google Scholar 

  • Moyer, S. A., Summers, D. F.: Phosphorylation of vesicular stomatitis virus in vivo and in vitro. J. Virol. 13, 455–465 (1974a)

    PubMed  CAS  Google Scholar 

  • Moyer, S. A., Summers, D. F.: Vesicular stomatitis virus envelope glycoprotein alterations induced by host cell transformation. Cell 2, 63–70 (1974b)

    Article  PubMed  CAS  Google Scholar 

  • Moyer, S. A., Banerjee, A. K.: Messenger RNA species synthesized in vitro by the virion-associated RNA polymerase of vesicular stomatitis virus. Cell 4, 37–43 (1975a)

    Article  PubMed  CAS  Google Scholar 

  • Moyer, S.A., Abraham, G., Adler, R., Banerjee, A. K.: Methylated and blocked 5′-termini in vesicular stomatitis virus in vivo mRNAs. Cell 59–67 (1975b)

    Google Scholar 

  • Mudd, J. A., Summers, D. F.: Protein synthesis in vesicular stomatitis virus-infected HeLa cells. Virology 42, 328–340 (1970a)

    Article  PubMed  CAS  Google Scholar 

  • Mudd, J. A., Summers, D. F.: Polysomal ribonucleic acid of vesicular stomatitis virus infected HeLa cells. Virology 42, 958–968 (1970b)

    Article  PubMed  CAS  Google Scholar 

  • Mudd, J. A.: Effects of pH on the structure of vesicular stomatitis virus. Virology 55, 546–549(1973)

    Article  PubMed  CAS  Google Scholar 

  • Mudd, J. A.: Glycoprotein fragment associated with vesicular stomatitis virus after proteolytic digestion. Virology 62, 573–577 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Murphy, M. F., Lazzarini, R. A.: Synthesis of viral mRNA and polyadenylate by a ribonucleoprotein complex from extracts of VSV-infected cells. Cell 3, 77–84 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Nakai, T., Howatson, A. F.: The fine structure of vesicular stomatitis virus. Virology 35, 268–281 (1968)

    Article  PubMed  CAS  Google Scholar 

  • Ngan, J. S. C., Holloway, A. F., Cormack, D. V.: Temperature-sensitive mutants of vesicular stomatitis virus: Comparison of the in vitro RNA polymerase defects of group I and group IV mutants. J. Virol. 14, 765–772 (1974)

    PubMed  CAS  Google Scholar 

  • Nowakowski, M., Bloom, B. R., Ehrenfeld, E., Summers, D. F.: Restricted replication of vesicular stomatitis virus in human lymphoblastoid cells. J. Virol. 12, 1272–1278 (1973)

    PubMed  CAS  Google Scholar 

  • Obijeski, J. F., Simpson, R. W.: Conditional lethal mutants of vesicular stomatitis virus II. Synthesis of virus-specific polypeptides in non-permissive cells infected with “RNA-” host-restricted mutants. Virology 57, 369–377 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Obijeski, J. F., Marchenko, A. T., Bishop, D. H. L., Gilead, Z., Arens, M.Q., Bhaduri, S., Shanmugam, G., Green, M.: Tumor antigen specificity 01 a DNA-binding protein from cells infected with adenovirus 2. Nature 254, 533535 (1975), Murphy, F. A.: Comparative electrophoretic analysis of the virus proteins of four rhabdoviruses. J. Gen. Virol. 22, 21–33 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Penhoet, E., Olsen, C., Carlson, S., Lacorbiere, M., Nicolson, G. L.: Quantitative interaction of Ricinus communis agglutinin and concanavalin A with influenza and vesicular stomatitis virus and virus-infected normal and polyoma-transformed cells. Biochem. 13, 3561–3566 (1974)

    Article  CAS  Google Scholar 

  • Perlman, S. M., Huang, A. S.: RNA synthesis of vesicular stomatitis virus V. Interactions between transcription and replication. J. Virol. 12, 1395–1400 (1973)

    PubMed  CAS  Google Scholar 

  • Perrault, J., Holland, J. J.: Absence of transcriptase activity or transcription-inhibiting ability in defective interfering particles of vesicular stomatitis virus. Virology 50, 159–170(1972)

    Article  PubMed  CAS  Google Scholar 

  • Perrault, J., Kingsbury, D. T.: Inhibitor of vesicular stomatitis virus transcriptase in purified virions. Nature 248, 45–47 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Prevec, L., Kang, C. Y.: Homotypic and heterotypic interference by defective particles of vesicular stomatitis virus. Nature 228, 25–27 (1970)

    Article  PubMed  CAS  Google Scholar 

  • Pringle, C. R.: Genetic characteristics of conditional lethal mutants of vesicular stomatitis virus induced by 5 — azacytidine, and ethyl methane sulfonate. J. Virol. 5, 559–567 (1970)

    PubMed  CAS  Google Scholar 

  • Pringle, C. R., Duncan, I. B., Stevenson, M.: Isolation and characterization of temperature-sensitive mutants of vesicular stomatitis virus, New Jersey serotype. J. Virol. 8, 836–841 (1971)

    PubMed  CAS  Google Scholar 

  • Pringle, C. R., Wunner, W. H.: Genetic and physiological properties of temperature-sensitive mutants of Cocal virus. J. Virol. 12, 677–683 (1973)

    PubMed  CAS  Google Scholar 

  • Pringle, C. R.: Conditional lethal mutants of vesicular stomatitis virus. Current Topics in Microbiology and Immunology 69, 85–116 (1975)

    PubMed  CAS  Google Scholar 

  • Printz-Ané, C., Combard, A., Martinet, C.: Study of the transcription and the replication of vesicular stomatitis virus by using temperature-sensitive mutants. J. Virol. 10, 889–895 (1972)

    PubMed  Google Scholar 

  • Reichmann, M. E., Pringle, C. R., Follett, E. A. C.: Defective particles in BHK cells infected with temperature-sensitive mutants of vesicular stomatitis virus. J. Virol. 8, 154–160 (1971)

    PubMed  CAS  Google Scholar 

  • Reichmann, M. E., Villarreal, L. P., Kohne, D., Lensaw, J., Holland, J. J.: RNA polymerase activity and poly (A) synthesizing activity in defective T particles of vesicular stomatitis virus. Virology 58, 240–249 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Repik, P., Bishop, D. H. L.: Determination of the molecular weight of animal RNA viral genomes by nuclease digestion I. Vesicular stomatitis virus and its defective T particle. J.Virol. 12, 969–983 (1973)

    PubMed  CAS  Google Scholar 

  • Repik, P., Flamand, A., Clark, H. F., Obijeski, J. F., Roy, P., Bishop, D. H. L.: Detection of homologous RNA sequences among six rhabdovirus genomes. J. Virol. 13, 250–252 (1974)

    PubMed  CAS  Google Scholar 

  • Rhodes, D. P., Moyer, S. A., Banerjee, A. K.: In vitro synthesis of methylated messenger RNA by the virion-associated RNA polymerase of vesicular stomatitis virus. Cell 3, 327–333 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Roy, P., Bishop, D. H. L.: Initiation and direction of RNA transcription by vesicular stomatitis virus virion transcriptase. J. Virol. 11, 487–501 (1973a)

    PubMed  CAS  Google Scholar 

  • Roy, P., Bishop, D. H. L.: Nucleoside triphosphate phosphotransferases. A new enzyme activity of oncogenic and non-oncogenic “budding” viruses. Biochim. Biophys. Acta 235, 191–206 (1973b)

    Google Scholar 

  • Roy, P., Repik, P., Hefti, E., Bishop, D. H. L.: Complementary RNA species isolated from vesicular stomatitis (HR strain) defective virions. J. Virol. 11, 915–925 (1973)

    PubMed  CAS  Google Scholar 

  • Russ, G., Poláková, K.: The molecular weight determinations of proteins and glycoproteins of RNA enveloped viruses by Polyacrylamide gel elctrophoresis in SDS. Biochem. and Biophys. Res. Comm. 55, 666–672 (1973)

    Article  CAS  Google Scholar 

  • Schaffer, F. L., Soergel, M. E.: Molecular weight estimates of vesicular stomatitis virus ribonucleic acids from virions, defective particles, and infected cells. Arch. ges. Virusforsch. 39, 203–222 (1972)

    Article  PubMed  CAS  Google Scholar 

  • Schloemer, R.H., Wagner, R.R.: Sialoglycoprotein of vesicular stomatitis virus: Role of the neuraminic acid in infection. J. Virol. 14, 270–281 (1974)

    PubMed  CAS  Google Scholar 

  • Schloemer, R. H., Wagner, R. R.: Cellular adsorption function of the sialoglycoprotein of vesicular stomatitis virus and its neuraminic acid. J. Virol. 15, 882–893 (1975a)

    PubMed  CAS  Google Scholar 

  • Schloemer, R. H., Wagner, R.R.: Mosquito cells infected with vesicular stomatitis virus yield unsialylated virions of low infectivity. J. Virol. 15, 1029–1032 (1975b)

    PubMed  CAS  Google Scholar 

  • Schloemer, R. H., Wagner, R. R.: Association of vesicular stomatitis virus glycoprotein with membranes: Isolation and characterization of a lipophilic fragment of the glycoprotein. J. Virol. 16, 237–249 (1975c)

    PubMed  CAS  Google Scholar 

  • Simpson, R. W., Hauser, R. E., Dales, S.: Viropexis of vesicular stomatitis virus by L cells. Virology 37, 285–290 (1969)

    Article  PubMed  CAS  Google Scholar 

  • Simpson, R. W., Obijeski, J. F.: Conditional lethal mutants of vesicular stomatitis virus I. Phenotypic characterization of single and double mutants exhibiting host restriction and temperature-sensitivity. Virology 57, 357–368 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Sokol, F., Clark, H. F.: Phosphoproteins, structural components of rhabdoviruses. Virology 52, 246–263 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Sokol, F., Clark, H. F., Wiktor, T. J., McFalls, M. L.: Structural phosphoproteins associated with the rhabdo viruses. J. Gen. Virol. 24, 433–445 (1974a)

    Article  PubMed  CAS  Google Scholar 

  • Sokol, F., Tan, K. B., McFalls, M.. Madore, P.: Phosphate acceptor amino acid residues in structural proteins of rhabdo viruses. J. Virol. 14, 145–151 (1974b)

    PubMed  CAS  Google Scholar 

  • Soria, M., Huang, A. S.: Association of polyadenylic acid with messenger RNA of vesicular stomatitis virus. J. Mol. Biol. 77, 449–455 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Soria, M., Little, S. P., Huang, A. S.: Characterization of vesicular stomatitis virus nucleocapsids I. Complementary 40S RNA molecules in nucleocapsids. Virol. 61, 270–280(1974)

    Article  CAS  Google Scholar 

  • Stamminger, G., Lazzarini, R. A.: Analysis of the RNA of defective VSV particles. Cell 3, 85–93 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Stampfer, M., Baltimore, D., Huang, A. S.: Ribonucleic acid synthesis of vesicular stomatitis virus. I. Species of ribonucleic acid found in Chinese hamster ovary cells infected with plaque-forming and defective particles. J. Virol. 4, 154–161 (1969)

    PubMed  CAS  Google Scholar 

  • Stampfer, M., Baltimore, D.: Identification of the vesicular stomatitis virus large protein as a unique viral protein. J. Virol. 11, 520–526 (1973)

    PubMed  CAS  Google Scholar 

  • Strand, M., August, J. T.: Protein kinase and phosphate acceptor proteins in Rauscher murine leukemia virus. Nature N. Biol. 233, 137–140 (1971)

    CAS  Google Scholar 

  • Szilagyi, J. F., Pringle, C. R.: Effect of temperature-sensitive mutations on the virion-associated RNA transcriptase of vesicular stomatitis virus. J.Mol. Biol. 71, 281–291 (1972)

    Article  PubMed  CAS  Google Scholar 

  • Szilágyi, J.F., Uryvayev, L.: Isolation of an infectious ribonucleoprotein from vesicular Stomatitis virus containing an active RNA transcriptase. J. Virol. 11, 279–286 (1973)

    PubMed  Google Scholar 

  • Travers, A. A., Burgess, R. R.: Cyclic re-use of the RNA polymerase sigma factor. Nature (London) 322, 537–540 (1969)

    Article  Google Scholar 

  • Unger, J. T., Reichmann, M. E.: RNA synthesis in temperature-sensitive mutants of vesicular stomatitis virus. J. Virol. 12, 570–578 (1973)

    PubMed  CAS  Google Scholar 

  • Villarreal, L. P., Holland, J. J.: Synthesis of poly (A) in vitro by purifired virions of vesicular stomatitis virus. Nature, N.B. 246, 17–19 (1973)

    CAS  Google Scholar 

  • Villarreal, L. P., Holland, J. J.: Transcribing complexes in cells infected by vesicular stomatitis virus and rabies virus. J. Virol. 14, 441–450 (1974)

    PubMed  CAS  Google Scholar 

  • Wagner, R. R., Schnaitman, C. A., Snyder, R. M.: Structural proteins of vesicular stomatitis viruses. J. Virol. 3, 395–403 (1969a)

    PubMed  CAS  Google Scholar 

  • Wagner, R. R., Schnaitman, T. C., Snyder, R. M., Schnaitman, C. A.: Protein composition of the structural components of vesicular stomatitis virus. J. Virol. 3, 611–618 (1969b)

    PubMed  CAS  Google Scholar 

  • Wagner, R. R., Snyder, R. M., Yamazaki, S.: Proteins of vesicular stomatitis virus: Kinetics and cellular sites of synthesis. J. Virol. 5, 548–558 (1970)

    PubMed  CAS  Google Scholar 

  • Wagner, R. R., Heine, J. W., Goldstein, G., Schnaitman, C. A.: Use of antiviral-antiferritin hybrid antibody for localization of viral antigen in plasma membrane. J. Virol. 7, 274–277 (1971)

    PubMed  Google Scholar 

  • Wagner, R. R., Kiley, M. P., Snyder, R. M., Schnaitman, C. A.: Cytoplasmic compartmentalization of the protein and ribonucleic acid species of vesicular stomatitis virus. J.Virol. 9, 672–683 (1972a)

    PubMed  CAS  Google Scholar 

  • Wagner, R. R., Prevec, L., Brown, F., Summers, D. F., Sokol, F., MacLeod, R.: Classification of rhabdovirus proteins: a proposal. J. Virol. 10, 1228–1230 (1972b)

    PubMed  CAS  Google Scholar 

  • Wagner, R. R.: Reproduction of rhabdoviruses. In: Comprehensive Virology (eds. H. Fraenkel-Conrat and R. R. Wagner) Vol. 4. New York: Plenum 1975

    Google Scholar 

  • Walter, G., Mudd, J. A.: Iodination of vesicular stomatitis virus with lactoperoxidase. Virology 52, 574–577 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Watanabe, Y., Sakuma, S., Tanaka, S.: A possible biological function of the protein kinase associated with vaccinia and vesicular stomatitis virions. FEBS Letters 41, 331–334(1974)

    Article  PubMed  CAS  Google Scholar 

  • Weber, S. H., Dahlberg, J. E., Cottler-Fox, M., Heine, U.: Electron microscopy of single-stranded RNA from vesicular stomatitis virus. Virology 62, 284–287 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Wertz, G. W., Youngner, J. S.: Inhibition of protein synthesis in L cells infected with vesicular stomatitis virus. J. Virol. 9, 85–89 (1972)

    PubMed  CAS  Google Scholar 

  • Wertz, G. W., Levine, M.: RNA synthesis by vesicular stomatitis virus and a small plaque mutant: Effects of cyclohexamide. J. Virol. 12, 253–264 (1973)

    PubMed  CAS  Google Scholar 

  • Wiktor, T. J., Koprowski, H.: Rhabdovirus replication in enucleated host cells. J. Virol. 14, 300–306 (1974)

    PubMed  CAS  Google Scholar 

  • Wild, T. F.: Replication of vesicular stomatitis virus: the effect of purified interfering component. J. Gen. Virol. 17, 295–305 (1972)

    Article  PubMed  CAS  Google Scholar 

  • Wong, P. K. Y., Holloway, A. F., Cormack, D. V.: Characterization of three complementation groups of vesicular stomatitis virus. Virology 50, 829–840 (1972)

    Article  PubMed  CAS  Google Scholar 

  • Wunner, W. H., Pringle, C. R.: Protein synthesis in BHK 21 cells infected with vesicular stomatitis virus II. Ts mutants of the New Jersey serotype. Virology 50, 250–253 (1972a)

    Article  PubMed  CAS  Google Scholar 

  • Wunner, W. H., Pringle, C. R.: Comparison of structural polypeptides from vesicular stomatitis virus (Indiana and New Jersey serotypes) and Cocal virus. J. Gen. Virol. 16, 1–10 (1972b)

    Article  PubMed  CAS  Google Scholar 

  • Závada, J.: Pseudotypes of vesicular stomatitis virus with the coat of murine leukaemia and of avian myeloblastosis virus. J. Gen. Virol. 15, 183–191 (1972)

    Article  PubMed  Google Scholar 

  • Závada, J., Rosenbergova, H.: Phenotypic mixing of vesicular stomatitis virus with fowl plaque virus. Acta Virol. 16, 103–114 (1972)

    PubMed  Google Scholar 

  • Závada, J., Zavodska, E.: Complementation and phenotypic stabilization of vesicular stomatitis virus temperature-sensitive and thermolabile mutants by avian myeloblastosis virus. Intervirology 2, 25–32 (1973/74)

    Article  Google Scholar 

  • Zee, Y. C., Hackett, A. J., Talens, L.: Vesicular stomatitis virus maturation sites in six different host cells. J. Gen. Virol. 7, 95–102 (1970)

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Microbiology Department, The University of Virginia School of Medicine, Charlottesville, Virginia, 22901, USA

    S. U. Emerson

Authors
  1. S. U. Emerson
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Basle, Switzerland

    W. Arber  & N. K. Jerne  & 

  2. Philadelphia, USA

    W. Henle , P. Koldovský  & H. Koprowski ,  & 

  3. Martinsried, Germany

    P. H. Hofschneider

  4. London, UK

    J. H. Humphrey

  5. Copenhagen, Denmark

    O. Maaløe

  6. Gieβen, Germany

    R. Rott

  7. Wilhelmshaven, Germany

    H. G. Schweiger

  8. Rehovot, Israel

    M. Sela

  9. Prague, Czech Republic

    L. Syruček

  10. Los Angeles, USA

    P. K. Vogt

Rights and permissions

Reprints and permissions

Copyright information

© 1976 Springer-Verlag, Berlin · Heidelberg

About this chapter

Cite this chapter

Emerson, S.U. (1976). Vesicular Stomatitis Virus: Structure and Function of Virion Components. In: Arber, W., et al. Current Topics in Microbiology and Immunology. Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung, vol 73. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66306-2_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-66306-2_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-66308-6

  • Online ISBN: 978-3-642-66306-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation