Tangier-Krankheit

  • Gerd Assmann
Part of the Handbuch der inneren Medizin book series (INNEREN, volume 7 / 4)

Zusammenfassung

Die Tangier-Krankheit ist eine seltene autosomal rezessiv vererbte Stoffwechselstörung. Die Krankheit wurde 1961 erstmalig beschrieben (Fredrickson u.Mitarb., 1961; Fredrickson u. Altrocchi, 1962) und ist benannt nach Tangier Island (Virginia), einer der Ostküste der Vereinigten Staaten von Nordamerika vorgelagerten Insel in der Chesapeake Bay, wo die zuerst bekannt gewordenen Patienten geheimatet sind. Tangier Island wurde 1608 durch Captain John Smith entdeckt. Viele der dort lebenden Fischer und deren Familien sind Abkommen des Engländers John Crocket, der dort 1686 die erste Siedlungsgemeinschaft gründete.

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