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Die Wirkung des zentralen Analgetikums Fentanyl auf das prä- und postkapillare Gefässsystem beim Hund

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Zusammenfassung

Die Verabreichung von Opiaten ist gewöhnlich mit einem Abfall des Blutdruckes verbunden. Diese Hypotension ist die Folge einer peripheren Vasodilatation im praekapillaren Stromgebiet (1). Es kommt zu einem parallelen Abfall sowohl des systolischen als auch des diastolischen Druckes. Einige Autoren postulieren, daß eine direkte Wirkung der Opiate auf die glatte Gefäßmuskulatur ursächlich in Erwägung zu ziehen ist. Der überwiegende Teil der Untersucher hat jedoch nachgewiesen, daß die Freisetzung von Histaminen durch zentral angreifende Analgetika für eine Vasodilatation verantwortlich ist (3 – 13).

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Authors
  1. E. Freye
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Editors and Affiliations

  1. Linz, Austria

    H. Bergmann

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© 1975 Springer-Verlag Berlin Heidelberg

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Freye, E. (1975). Die Wirkung des zentralen Analgetikums Fentanyl auf das prä- und postkapillare Gefässsystem beim Hund. In: Bergmann, H., Blauhut, B. (eds) Intensivtherapie. Anaesthesiology and Resuscitation Anaesthesiologie und Wiederbelebung Anesthésiologie et Réanimation, vol 94. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66246-1_29

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  • DOI: https://doi.org/10.1007/978-3-642-66246-1_29

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-07479-3

  • Online ISBN: 978-3-642-66246-1

  • eBook Packages: Springer Book Archive

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