Binding and Gating by the Acetylcholine Receptor

  • Arthur Karlin
  • Mark G. McNamee
  • Cheryl L. Weill


The receptors for acetylcholine transduce the binding of acetylcholine into permeability changes of postsynaptic membranes. Although there has been much progress in the development of means of identification of the receptors in isolation and in their purification and gross characterization (see review by KARLIN, 1974), the mechanisms of the transductions and of the ionic permeation processes remain undetermined.


Acetylcholine Receptor Cholinergic Receptor Affinity Label Ammonium Iodide Receptor Preparation 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1975

Authors and Affiliations

  • Arthur Karlin
    • 1
  • Mark G. McNamee
    • 1
  • Cheryl L. Weill
    • 1
  1. 1.Department of Neurology, College of Physicians and SurgeonsColumbia UniversityNew YorkUSA

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