Skip to main content

Tumoren des Pankreas

  • Chapter
Book cover Pankreas

Part of the book series: Handbuch der inneren Medizin ((INNEREN 3,volume 3 / 6))

  • 28 Accesses

Zusammenfassung

Als Einteilungsprinzip kann

  1. a)

    die Matrix,

  2. b)

    die Differenzierungshöhe und

  3. c)

    die Prognose (gutartig/bösartig) genannt werden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Aepli, R.: A propos d’un pseudo-kyste pancréatique simulant une tumeur abdominale maligne. J. suisse Méd. 92, 479 (1962).

    CAS  Google Scholar 

  • Aird, J., Lee, D.R., Roberts, J.A.F.: ABO blood groups and cancer of oesophagus, cancer of pancreas, and pituitary adenoma. Brit. med. J. 1960 I, 1163.

    Google Scholar 

  • Alcantara, E.N., Jr.: Functioning acinar cell carcinoma of the pancreas. Canad. med. Ass. J. 87, 970–973 (1962).

    PubMed  Google Scholar 

  • Alfidi, R.J., Skillern, P.F., Crile, G.: Arteriographic manifestations of the Zollinger-Ellison-syndrome. Cleveland Clin. Quart. 36, 41–45 (1969).

    PubMed  CAS  Google Scholar 

  • Amunni, G.F.: Il profilo anatomo-isto-patologico dei tumori mesenchimali primitivi maligni del pancreas. Contributo casistico sarcoma fuso-cellulare e linfosarcoma. Arch. ital. Mal. Appar. dig. 18, 79 (1952).

    PubMed  CAS  Google Scholar 

  • Anacker, H., Weiss, H.-D., Wiesner, W.: Das pankreatikographische Bild der entzündlichen Pankreasprozesse. Fortschr. Röntgenstr. 117, 4, 418–424 (1972).

    CAS  Google Scholar 

  • Ansari, A., Burch, G.E.: Correlative study of proven carcinoma of the pancreas in 83 patients. Amer. J. Gastroent. 50, 456–475 (1968).

    PubMed  CAS  Google Scholar 

  • Arnold, R., Fuchs, K., Siewert, R., Peiper, H.-J., Creutzfeldt, W.: Zur Morphologie, Klinik, Diagnostik und Therapie des Zollinger-Ellison-Syndroms. Dtsch. med. Wschr. 99, 607–614 (1974).

    PubMed  CAS  Google Scholar 

  • Aronsen, K.F., Boquist, L., Falkmer, S., Hägerstrand, I., Steiner, H., Studnitz, W. von: Carcinoid syndrome and hyperinsulinism. Acta path. microbiol. scand. 78, 265–276 (1970).

    CAS  Google Scholar 

  • Assan, R., Rosselin, G., Tchobroutsky, G., Barbanel, C., Vaysse, J., Faye, C., Aubert, P., Tourneur, R.: Hypoglycémie organique avec association d’une tumeur maligne renale et d’un adenome Langerhansien. Role determinant des dosages d’insulinemie pour le diagnostic etiologi-que et la conduite chirugicale. Presse med. 77, 1039–1041 (1969).

    PubMed  CAS  Google Scholar 

  • Ayella, A.S., Jr., Howard, J.M., Grotzinger, P.J.: Cystadenoma and cystadenocarcinoma of the pancreas: Amer. J. Surg. 103, 242 (1962).

    Google Scholar 

  • Balls, K.F., Nicholson, J.T.L., Goodman, H.L., Touchstone, J.C.: Functioning islet-cell carcinoma of the pancreas with cushing’s syndrome. J. clin. Endocr. 19, 1134 (1959).

    PubMed  CAS  Google Scholar 

  • Bank, S., Marks, I.N., Searly, R.: Malignant Zollinger-Ellison syndrome in a Bantu woman with a prolonged remission after gastric radiotherapy. Gut 6, 279–285 (1965).

    PubMed  CAS  Google Scholar 

  • Bankl, H., Grunert, V., Sunder-Plassmann, M.: Endokrine Polyadenomatose kombiniert mit einem Tentoriummeningeom. Wien. klin. Wschr. 82, 257–259 (1970).

    PubMed  CAS  Google Scholar 

  • Barbier, P., Jacobs, E.: Carcinomas du pancréas et troubles de la glycorégulation. Acta gastroent. belg. 28, 568–572 (1965).

    PubMed  CAS  Google Scholar 

  • Barris, R.W.: Pancreatic adenoma associated with neuromuscular disorders. Ann. intern. Med. 38, 124 (1953).

    PubMed  CAS  Google Scholar 

  • Bassermann, R., Bürger, L.: Heilung von Krankheit durch Trauma. Therapiewoche 23, 2985–2986 (1973).

    Google Scholar 

  • Becker, H.D., Reeder, D.D., Thompson, J.C.: Effect of glucagon on circulating gastrin. Gastroenterology 65, 28–35 (1973).

    PubMed  CAS  Google Scholar 

  • Becker, V.: Tryptische Pankreatitis und tryptische Nekrose. Dtsch. med. Wschr. 89, 671–676, (1964).

    PubMed  CAS  Google Scholar 

  • Becker, V.: Tryptische Pankreatitis und tryptische Nekrose. Dtsch. med. Wschr. 89, u. Bild. 689–690 (1964).

    Google Scholar 

  • Becker, V.: Pathologische Anatomie und Pathogenese des Zollinger-Ellison-Syndroms. Demonstration und Deduktion. Rev. int. Hépat. 15, 509–516 (1965).

    PubMed  CAS  Google Scholar 

  • Becker, V.: Das Zollinger-Ellison-Syndrom Paradigma der Oberbaucheinheit. Therapiewoche 15, 767–771 (1965).

    PubMed  CAS  Google Scholar 

  • Becker, V.: Über den Zollinger-Ellison-Mechanismus. Klin. Wschr. 44, 370–375 (1966).

    PubMed  CAS  Google Scholar 

  • Becker, V.: Funktionelle Morphologie der Bauchspeicheldrüse dargestellt an seltenen Krankheitsbildern. Med. Welt 18, 1711–1719 (1967).

    Google Scholar 

  • Becker, V.: Das Zollinger-Ellison-Syndrom. Wiener klin. Wschr. 79, 577–579 (1967).

    CAS  Google Scholar 

  • Becker, V.: Pathologisch-anatomische Aspekte bei endokrin wirksamen Tumoren. Langenbecks Arch. klin. Chir. 88. Kongr.-Bd., 329–437 (1971).

    Google Scholar 

  • Becker, V.: Bauchspeicheldrüse (Inselapparat ausgenommen). In: Doerr-Seifert-Uehlinger, Spezielle pathologische Anatomie, Bd. 6. Berlin-Heidelberg-New York: Springer 1973.

    Google Scholar 

  • Becker, V., Schneider, H.H.: Das Wermer-Syndrom. Dtsch. med. Wschr. 93, 935–939 (1968).

    PubMed  CAS  Google Scholar 

  • Becker, V., Seelig, H.P.: Pathologic anatomy and pathophysiology of the Zollinger-Ellison-syndrome. In: Demling-Ottenjann, Non-insulin-producing tumors of the pancreas. Intern. Sympos. at Erlangen, 1968, p. 49–60. Stuttgart: Gg. Thieme 1969.

    Google Scholar 

  • Becker, W.H.: Phasenkontrastmikroskopie in der histologischen Schnellschnittdiagnostik. In: Hermanek-Bünte, Die intraoperative Schnellschnittuntersuchung. München-Berlin-Wien: Urban & Schwarzenberg 1972.

    Google Scholar 

  • Behrendt, W.: Ein Beitrag zur Pathologie des A-Zellkarzinoms. Zbl. allg. Path. path. Anat. 104, 199–204(1963).

    CAS  Google Scholar 

  • Bell, E.T.: Carcinoma of the pancreas. I. A clinical and pathologic study of 609 necropsied cases. II. The relation of carcinoma of the pancreas to Diabetes mellitus. Amer. J. Path. 33, 499 (1957).

    PubMed  CAS  Google Scholar 

  • Berman, J.K., Levene, N.: Sarcoma of the pancreas. Arch. Surg. 73, 894 (1956).

    CAS  Google Scholar 

  • Bernades, P., Mignon, M., Bensalem, R., Dubrasquet, M., Bader, J.P., Bonfils, S.: Discriminative interest of the study of basal acid secretion and pepsin acid correlation in Zollinger-Ellison and peptic ulcer. Digestion 9, 1–8 (1973).

    PubMed  CAS  Google Scholar 

  • Bernier, J.-J., Bouvry, M., Rambaud, J.C., Duret, P.: Entéropathie exsudative et grêle fonctionale au cours de deux cas de cancer du pancréas avec obstructions vasculaires. Rev. méd. Toulouse 4, 17–24 (1968).

    Google Scholar 

  • Berson, S.A., Walsh, J.H., Yalow, R.S.: Radioimmunoassay of gastrin in human plasma and regulation of gastrin secretion. In: Nobel Symposium 16: Frontiers in gastrointestinal hormone research, ed. by S. Andersson, p. 57–66. Stockholm: Almqvist & Wiksell 1973.

    Google Scholar 

  • Berson, S.A., Yalow, R.S.: Nature of immunoreactive gastrin extracted from tissues of gastrointestinal tract. Gastroenterology 60, 215–222 (1971).

    PubMed  CAS  Google Scholar 

  • Berson, S.A., Yalow, R.S.: Radioimmunoassay in gastroenterology. Gastroenterology 62, 1061–1084(1972).

    PubMed  CAS  Google Scholar 

  • Bieber, W.P., Albo, R..J.: Cystadenoma of the pancreas: Its arteriographic diagnosis. Radiology 80,776–778(1963).

    PubMed  CAS  Google Scholar 

  • Block, Melvin, Kelly, A., Horn, R.C.: Elevation of multiple humoral substances in Zollinger-Ellison-Syndrom. Arch. Surg. 98, 734–737 (1969).

    PubMed  CAS  Google Scholar 

  • Bloom, S.R., Polak, J.M., Pearse, A.G.E.: Vasoactive intestinal peptide and waterydiarrhea syndrome. Lancet 1973 II, 14–16.

    Google Scholar 

  • Bode, O., Probst, J.: Metastasierendes Adenocarcinom des Pankreas mit Hyperinsulinismus. Z. klin. Med. 150, 469 (1953).

    PubMed  CAS  Google Scholar 

  • Bodner, E., Lederer, B., Margreiter, D.: Ganglioneurom und Insulinom im Pankreas. Zufälliges oder induziertes gemeinsames Auftreten? Chirurg 43, 420–422 (1972).

    PubMed  CAS  Google Scholar 

  • Böck, J., Feyrter, F.: Zur Frage der Endokrinie der myothelialen und epimyothelialen Geschwülste der Speichel- und Tränendrüsen. Wien. med. Wschr. 114, 36, 609 (1964).

    Google Scholar 

  • Böhm, N., Nägele, E., Grundner, H.G., Wagner, E., Beneke, G.: Syndrom multipler endokriner Hyperplasien und Adenome (MEHA-Syndrom) mit Zollinger-Ellison-Syndrom. Med. Welt 18, 2633–2640 (1967).

    Google Scholar 

  • Bonfils, S.: New data on non-B cell tumors of the pancreas. In: Diabetes. Proceedings, VIII. Congress of the internat. Diab. Federation. Hrsg. W.J. Malaisse, U. J. Pirrat, p. 703–713. Amsterdam: Excerpta Medica 1974.

    Google Scholar 

  • Bonfils, S., Bader, J.P.: The diagnosis of Zollinger-Ellison syndrome with special reference to the multiple endocrine adenomas. In: Progress in gastroenterology. Vol. 2, p. 332–355. Hrsg. J.G.B. Glass. New York: Grüne und Statton 1970.

    Google Scholar 

  • Bonfils, S., Bernades, P.: Zollinger-Ellison syndrome: natural history and diagnosis. Clinics in Gastroent. 3, 533–538 (1974).

    Google Scholar 

  • Bookmann, M.R.: Carcinoma in the duodenum originating from aberrant pancreatic cells. Ann. Surg. Bookmann, M.R.: Carcinoma in the duodenum originating from aberrant pancreatic cells. Ann. Surg. 95, 464–467 (1932).

    Google Scholar 

  • Boucher, B.J., Frankel, R..J., Walters, P., Abel, M.: Rate of disappearance of endogenous insulin from the circulation after removal of insulinomas. Brit. med. J. 1970, No. 5695, 535–537.

    Google Scholar 

  • Bowden, L., Papanicolaou, G.N.: The diagnosis pancreatic cancer by cytologic study of duodenal secretions. Acta Un. int. Cancr. 16, 398 (1960).

    PubMed  CAS  Google Scholar 

  • Britt, R.P.: Pedunculated islet-cell tumor the duodenum. J. clin. Path. 19, 272–274 (1966).

    PubMed  CAS  Google Scholar 

  • Brown, Ch.H., Crile, G.: Pancreatic adenoma with intractable diarrhea, hypokalemia, and hypercalcemia. J. Amer. med. Ass. 190, 30–34 (1964).

    CAS  Google Scholar 

  • Brown, J.C., Dryburgh, J.R.: A gastric inhibitory polypeptide. II. The complete amino acid sequence. Canad. J. Biochem. 49, 867–872 (1971).

    CAS  Google Scholar 

  • Brown, J.C., Dryburgh, J.R., Pedersen, R.A.: Gastric inhibitory polypeptide (GIP). In: Endocrinology of the gut, p. 76–82. Hrsg. W.Y. Chey, U. F.B. Brooks. Thorofare/New Yersey: Ch. B. Slack, Inc. 1974.

    Google Scholar 

  • Bryant, L.R., Moore, Th.C., Carney, E.K.: Islet cell adenomas of the duodenum with recurrent peptic ulceration (Zollinger-Ellison). Ann. Surg. 160, 1, 104–107 (1964).

    PubMed  CAS  Google Scholar 

  • Bück, G.: Contribution á l’etude des tumeurs du pancréas chez les animaux. Thèse, Lyon 1930.

    Google Scholar 

  • Burke, G., Finer, J.R., Sandlow, L..J.: Ulcerogenic tumor of the pancreas and hyperparathyroidism. Gastroenterology 47, 88–96 (1964).

    PubMed  CAS  Google Scholar 

  • Burkhardt, L.: Inselneubildung im Pankreas bei Stenose des Ausführungsganges durch Pankreas-kopfcarcinom. Virchows Arch. path. Anat. 296, 655–665 (1936).

    Google Scholar 

  • Burmester, H.B.C., Hall, R., Munawer, N.: The Zollinger-Ellison syndrome in a child. Gut 10, 800–803(1969).

    PubMed  CAS  Google Scholar 

  • Buse, J., Marshall, J.N., Bradham, R., Oberman, H., Buse, M.G.: Functioning pancreatic islet cell adenoma. With leucine-induced hypoglycemia. Arch, intern. Med. 112, 584–588 (1963).

    CAS  Google Scholar 

  • Cambpell,J.A., Cruickshank, A.H.: Cystadenoma and cystadenocarcinoma of the pancreas. J. clin. Path. 15, 432–437 (1962).

    Google Scholar 

  • Cathcart, R.S., Webb, C.M., Othersen, H.B.: Zollinger-Ellison-Syndrom in a seven-year old boy: A case report. Surgery 66, 410 (1969).

    Google Scholar 

  • Charles, B., Cochrane, W.A.: Islet cell tumor of the pancreas with chronic diarrhoea and hypokalae-mia; a recently recognized syndrome. Canad. med. Ass. J. 82, 579 (1960).

    PubMed  CAS  Google Scholar 

  • Chevrel, B.: Sarcome du pancréas. Ann. Chir. 22, 199–203 (1968).

    PubMed  CAS  Google Scholar 

  • Chvojka, E.: Islet-cell tumors and peptic ulcers: case report of the Zollinger-Ellison-syndrome. Ann. intern. Med. 53, 1180 (1960).

    PubMed  CAS  Google Scholar 

  • Clark, Ch.G., Mitchell, P.E.G.: Diabetes mellitus and primary carcinoma of the pancreas. Brit. med. J. 1961, 11, 1259.

    Google Scholar 

  • Classen, M., Gail, K., Breining, H., Demling, L.: Verner-Morrison-Syndrom (pankreatische Cholera, WDHA-Syndrom) . Dtsch. med. Wschr. 97, 277–283 (1972).

    PubMed  CAS  Google Scholar 

  • Claude, H., Baudoin, A.: Etude histologique des glandes à sécrétion interne dans un cas d’acromégalie. C.R. Soc. Biol. (Paris) 71, 75 (1911).

    Google Scholar 

  • Cleator, I.G.M., Thomson, C.G., Sircus, W., Coombes, M.: Bio-assay evidence of abnormal secretin-like and gastrin-like activity in tumour and blood in cases of “choleraic diarrhoea”. Gut 11, 206–211(1970).

    PubMed  CAS  Google Scholar 

  • Code, C.F., Hallenbeck, A., Summerskill, W.H.J.: Extraction of a gastric secretagogue from primary and metastatic tumors in two cases of Zollinger-Ellison-syndrome. J. surg. Res. 2, 136 (1962).

    PubMed  CAS  Google Scholar 

  • Cohen, B.D., Lubash, G.D., Rubin, A.L.: Parathyroid and pancreatic adenomas. Amer. J. Med. 26, 801(1959).

    PubMed  CAS  Google Scholar 

  • Colwell, J.A., Furey, W.L.: Insulin secretion by insuloma and normal pancreas slices. Studies in a patient with multiple endocrine adenomata. Diabetes 17, 2, 83–88 (1968).

    PubMed  CAS  Google Scholar 

  • Conte, M., Godeau, P.: Cancer du pancréas et du diabète. Presse méd. 68, 2331–2332 (1960).

    PubMed  CAS  Google Scholar 

  • Cook, H.B., French, A.B.: Physiologic responses to gastric acid hypersecretion in Zollinger-Ellison syndrome. Amer. J. dig. Dis. 13, 191–203 (1968).

    PubMed  CAS  Google Scholar 

  • Cooke, W.T., Fowler, D.I., Gaddie, R., Cox, E.V., Meynell, M.J., Brewer, D.: Multiple endocrine adenoma syndrome. Gut 1, 71 (1960).

    PubMed  CAS  Google Scholar 

  • Cornes, J.S., Azzopardi, J.G.: Papillary cystadenocarcinoma of the pancreas. With report of two cases. Brit. J. Surg. 47, 139 (1959).

    CAS  Google Scholar 

  • Coskey, R.L., Tranquada, R.E.: Insulinoma and multiple neurofibromatosis: Report of a case. Metabolism 13, 312–318 (1964).

    PubMed  CAS  Google Scholar 

  • Cowley, D.J., Dymock, I.W., Boyes, B.E., Wilson, R.Y., Stagg, B.H., Lewin, M.R., Polak, J.M., Pearse, A.G.E.: Zollinger-Ellison syndrome type I: clinical and pathological correlations in a case. Gut 14, 25–29 (1973).

    PubMed  CAS  Google Scholar 

  • Creutzfeldt, W.: Zur Deutung des Silberbildes und anderer Pankreasbefunde beim Diabetes und Inseladenom. Beitr. path. Anat. 113, 133–168 (1953).

    CAS  Google Scholar 

  • Creutzfeldt, W.: Klinik der chronischen Pankreatitis. In: Henning-Heinkel-Schön, Pathogenese, Diagnostik, Klinik und Therapie des exokrinen Pankreas. Stuttgart: Schattauer 1964.

    Google Scholar 

  • Creutzfeldt, W. (Hrsg.): Origin, chemistry, physiology and pathophysiology of the gastrointestinal hormones. Stuttgart-New York: F.K. Schattauer 1970.

    Google Scholar 

  • Creutzfeld, W., Creutzfeldt, C., Arnold, R.: Gastrin-producing cells. In: Endocrinology of the gut. Ed. by W.Y. Chey and F.O. Brooks, p. 35–62. Thorofare/New Yersey: Ch. B. Slack, Inc. 1974.

    Google Scholar 

  • Creutzfeldt, W., Frerichs, H., Ketterer, H., Feurle, G., Arnold, R.: Die klinischen Syndrome hormonal aktiver Pankreastumoren. Chirurg 42, 97–105 (1971).

    PubMed  CAS  Google Scholar 

  • Creutzfeldt, W., Kern, E., Kümmerle, F., Schumacher, J.: Die radikale Entfernung der Bauchspeicheldrüse beim Menschen, Indikation, Ergebnisse, Folgeerscheinungen. Ergebn. inn. Med. Kinder-heilk., N.F. 16, 79–124(1961).

    CAS  Google Scholar 

  • Croisier, J.-C., Azerad, E., Lubetzki, J.: L’adenomatose polyendocrinienne (Syndrome de Wermer). A propos d’une observation personelle. Revue de la littérature. Sem. Hôp. (Paris) 47, 494–525 (1971).

    PubMed  CAS  Google Scholar 

  • Croisier, J.C., Lehy, T., Zeitoun, P.: A2 cell pancreatic microadenomas in case of multiple endocrine adenomatosis. Cancer (Philad.) 28, 707–713 (1971).

    CAS  Google Scholar 

  • Croughs, R.J.M.: Glucagonoma and A-cell hyperplasia. Clinics in Gastroent. 3, 609–619 (1974).

    Google Scholar 

  • Cullen, P.K., Jr., ReMine, W.H., Dahlin, D.C.: A clinicopathological study of cystadenocarcinoma of the pancreas. Surg. Gynec. Obstet. 117, 189–195 (1963).

    PubMed  Google Scholar 

  • Cunningham, L., Hawe, P., Evans, R.W.: Islet cell tumours of the pancreas with unusual clinicopathological features. Brit. J. Surg. 39, 319 (1952).

    PubMed  CAS  Google Scholar 

  • Danowski, T.S., Mateer, F.M., Longabaugh, E.E.: Endocrine adenomatosis (polyendocrine disease) familial occurences. Acta med. scand. 172, 559–566 (1962).

    PubMed  CAS  Google Scholar 

  • Davidson, P., Costanza, D., Swieconek, J.A., Harris, J.B.: Hereditary pancreatitis. A kindred without gross aminoaciduria. Ann. intern. Med. 68, 88–96 (1968).

    PubMed  CAS  Google Scholar 

  • Davis, Ch.E., Jr., Smith, E.P., Jr., Davalos, X.S.: Ulcerogenic tumor of the pancreas. Ann. Surg. 155, 669–680 (1962).

    PubMed  Google Scholar 

  • Debray, Ch., Bricaire, H., Hardouin, J.-P., Rambaud, J.-C.: Adénome parathyroidien avec lithiase rénale associé à une adenomatose pancréatique non insulinogène hypersécrétion gastrique et ulcers peptiques récidivants (Syndrome de Zollinger-Ellison). Ann. Endocr. (Paris) 25, 401–416 (1964).

    CAS  Google Scholar 

  • Delarue, J., Gouygou, C., Etévé, J.: Carcinomes gastriques à differenciation pancréatique: Arch. Mal. Appar. dig. 45, 506 (1956).

    PubMed  CAS  Google Scholar 

  • Demling, L., Otterjann, R.: Non-insulin-producing tumors of the pancreas. Modern aspects on Zollinger-Ellison syndrome an gastrin. Internat. Sympos. at Erlangen 1968. Stuttgart: Georg Thieme 1969.

    Google Scholar 

  • Dengler, H.: Atypisches Carcinoidsyndrom mit vermehrter Ausscheidung von 5-Hydroxyndolessig-säure bei Pankreascarcinom. Klin. Wschr. 37, 1245 (1959).

    PubMed  CAS  Google Scholar 

  • Derom, F., Ringoir, S., Marlier, R.: Deux cas d’hémangiome intra-abdominal: foie et pancréas. Acta chir. belg. 59, 172–182 (1960).

    PubMed  CAS  Google Scholar 

  • Dimagno, E.P., Go, V.L.: Malabsorption secondary to antral gastrin-cell hyperplasia. Mayo Clin. Proc. 49, 727–730 (1974).

    PubMed  CAS  Google Scholar 

  • Döring, Ch., Lindlar, F.: Klinisch primäres Lungencarcinom autoptische Metastase eines Pankreas-carcinom. Med. Welt 20 (N.F.), 407–411 (1969).

    Google Scholar 

  • Dörken, H.: Einige Daten bei Patienten mit Pankreaskrebs. Gastroenterologia (Basel) 102, 47–77 (1964).

    Google Scholar 

  • Dörken, H.: Epidemiologie und Klinik des Pankreaskrebses. Internist (Berl.) 11, 122–127 (1970).

    Google Scholar 

  • Doerr, W., Becker, V.: Bauchspeicheldrüse. In: Cohrs-Jaffé-Meessen, Pathologie der Laboratoriumstiere. Berlin-Göttingen-Heidelberg: Springer 1958.

    Google Scholar 

  • Dollinger, M.R., Ratner, L.H., Shamoian, CA., Blackbourne, B.D.: Carcinoid syndrome associated with pancreatic tumors. Arch, intern. Med. 120, 575–580 (1967).

    CAS  Google Scholar 

  • Douglas, H.O., Sika, J.V., Le Veen, H.H.: The significance of pancreatic heterotopia in relation to cancer of the head of the pancreas. Gastroenterology 59, 860–861 (1970).

    Google Scholar 

  • Dowd, J.B.: Carcinoma of the pancreas presenting as obstructing cancer of the prostata. Lahey Clin. Bull. 13, 204–205 (1964).

    CAS  Google Scholar 

  • Dreiling, D.A., Blum, L., Sanders, M.: Thrombophlebitis, blood coagulation and pancreatic disease. Arch. intern. Med. 96, 490–495 (1955).

    CAS  Google Scholar 

  • Dreiling, D.A., Greenstein, A.: Pancreatic function in patients with the Zollinger-Ellison syndrome. Observations concerning acid-bicarbonate secretion. Med. Chir. Dig. 1, 1–4 (1972).

    PubMed  CAS  Google Scholar 

  • Dry, J., Roland, J., Bourdarias, J., Holler, A., Harlay, A.: La Polyadénomatose avec tumeur pancréatique â stroma amyloide. Nouvelle Presse méd. 1, 1341–1345 (1972).

    CAS  Google Scholar 

  • Duff, G.L., Forster, H.L., Bryan, W.W.: Primary carcinoma of the infraampullary portion of the duodenum. Arch. Surg. 46, 494–503 (1943).

    Google Scholar 

  • Dutta, P., Wallace, M.R.: Familial multiple endocrine adenopathy (primary hyperparathyreoidism and Zollinger-Ellison syndrome) in two siblings. Proc. roy. Soc. Med. 61, 658–660 (1968).

    PubMed  CAS  Google Scholar 

  • Dyck, W.P.: Pancreatic hypersecretion in the Zollinger-Ellison syndrome. Case Report. Gastroenterology 60, 90–95 (1971).

    CAS  Google Scholar 

  • Ebhardt, Kl.: Pankreasinselzelladenomund Carcinom, Langenbecks Arch. klin. Chir. 206, 233–236 (1944).

    Google Scholar 

  • Edmeads, J.G., Mathews, R.E., McPhedran, N.T., Ezrin, C.: Diarrhea caused by pancreatic islet cell tumours. Canad. med. Ass. J. 86, 847 (1962).

    PubMed  CAS  Google Scholar 

  • Eiseman, B.: Diskussionsbemerkung zu Ellison, 1956. Surgery 40, 169 (1956).

    Google Scholar 

  • Eiseman, B., Maynard, R.M.: A non-insulin producing islet cell adenoma associated with progressive peptic ulceration (the Zollinger-Ellison syndrome). Case report. Gastroenterology 31, 296–304 (1956).

    CAS  Google Scholar 

  • Elias, E., Polak, J.M., Bloom, S.R., Pearse, A.G.E., Welbourn, R.B., Booth, C.C., Kuzio, M., Brown, J.C.: Pancreatic cholera due to production of gastric inhibitory polypeptide. Lancet 1972 II,791–793.

    Google Scholar 

  • Ellison, E.H.: The ulcerogenic tumor of the pancreas. Surgery 40, 147–169 (1956).

    PubMed  CAS  Google Scholar 

  • Ellison, E.H., Wilson, S.D.: The Zollinger-Ellison syndrome: re-appraisal and evaluation of 260 registered cases. Ann. Surg. 160, 512 (1964).

    PubMed  CAS  Google Scholar 

  • Ellison, E.H., Wilson, S.D.: Ulcerogenic tumor of the pancreas. Proc. Clin. Cancer 3, 225–244 (1967).

    CAS  Google Scholar 

  • Emås, E., Fyrö, B.: Gastrin-like activity in different parts of the gastrointestinal tract of the cat. Acta physiol. scand. 74, 359–367 (1968).

    PubMed  Google Scholar 

  • Enderlin, F.: Das Zollinger-Ellison-Syndrom. Ergebn. Chir. Orthop. 44, 112–143 (1962).

    Google Scholar 

  • Enderlin, F.: Ulcerogene Tumoren des Pankreas. Praktisch-klinische Aspekte. Helv. chir. Acta 31, 294–303 (1964).

    CAS  Google Scholar 

  • Enderlin, F.: Einige Aspekte des Zollinger-Ellison-Syndroms aus chirurgischer Sicht. Chirurg 42, 106–111(1971).

    PubMed  CAS  Google Scholar 

  • Erdheim, J.: Zur normalen und pathologischen Histologie der Glandula thyreoidea, parathyreoidea und Hypophysis. Zieglers Beitr. path. Anat. 33, 158–236 (1903).

    Google Scholar 

  • Fahri, A., Sédad, A.: Contribution â l’étude des tumeurs malignes de la queue du pancréas. Schweiz. med. Wschr. 59, 412(1929).

    Google Scholar 

  • Feurle, G.: Gastrin: Neue Ergebnisse. In: Gastroenterologie und Stoffwechsel, Aktionen und Interaktionen, Hrsg. V. Becker, S. 230–234. Baden-Baden-Brüssel: Gerhard Witzstrock GmbH 1974.

    Google Scholar 

  • Feyrter, F.: Über die peripheren endokrinen (parakrinen) Drüsen des Menschen. Wien: Maudrich 1953.

    Google Scholar 

  • Feyrter, F.: Zur Frage des Zollinger-Ellison-Syndroms. Klin. Wschr. 40, 1085 (1962).

    PubMed  CAS  Google Scholar 

  • Finlay, J.M., Mortimer, D.C., Vidinli, M.C., Yendt, E.R., McPhedran, N.T.: Coexistent Zollinger-Ellison-syndrome (polyglandular endocrine adenomatosis) and renal tubular acidosis: A case report. Gastroenterology 44, 824 (1963).

    Google Scholar 

  • Fish, G.D., Jr., Isham, W.H., Tucker, F.C.: Hyperinsulinism due to hyperplasia of the islets of Langerhans. Illinois med. J. 120, 290 (1961).

    Google Scholar 

  • Fisher, E.R., Flandreau, R.H.: Multiple endocrine tumors and peptic ulcers. Gastroenterology 32, 1075–1094(1957).

    PubMed  CAS  Google Scholar 

  • Fisher, E.R., Hicks, J.: Further pathologic observations on the syndrome of peptic ulcer and multiple endocrine tumors. Gastroenterology 38, 458–466 (1960).

    PubMed  CAS  Google Scholar 

  • Flanagan, G.C., Schwartz, Th.B., Ryan, W.G.: Studies on patients with islet-cell tumor, includung the phenomenon of leucine-induced accentuation of hypoglycemia. J. clin. Endocr. 21, 401 (1961).

    PubMed  CAS  Google Scholar 

  • Fontaine, R., Lang, G., Babin, S., Philippe, E.: A propos de deux cas de syndrome de Zollinger-Ellison. Rev. int. Hépat. 16, 669–685 (1966).

    PubMed  CAS  Google Scholar 

  • Forsgren, L., Hansson, K., Lundh, G., Nordenstam, H.: Pancreatic biopsy. Arch. Chir. Scand. 134,457–460(1968).

    CAS  Google Scholar 

  • Forssmann, W.G.: Morphologie der Polypeptid-Hormonbildenden endokrinen Zellen des Magendarmtraktes. In: Gastroenterologie und Stoffwechsel, Aktionen und Interaktionen, Hrsg. V. Bekker, S. 210–225. Baden-Baden-Brüssel: Gerhard Witzstrock, GmbH 1974.

    Google Scholar 

  • Forty, F., Barrett, G.M.: Peptic ulceration of the third part of the duodenum associated with islet-cell tumours of the pancreas. Brit. J. Surg. 40, 60–63 (1952).

    PubMed  CAS  Google Scholar 

  • Franke, H., Kern, E.: Komplikationen bei der operativen Behandlung von Pankreaszysten. Chirurg 25,73–77(1954).

    PubMed  CAS  Google Scholar 

  • Franksson, C., Hellström, J., Hultquist, G., Perman, G.: Primary chief-cell hyperplasia of the parathyroids, and islets cell hyperplasia and adenomata of the pancreas associated with gastro-duodeno-jejunal ulcer. Acta chir. scand. 118, 270 (1960).

    PubMed  CAS  Google Scholar 

  • Frantz, V.K.: Tumors of the pancreas. In: Atlas of tumor pathology, sect. VII, fasc. 27–28. Washington: Armed Forces Institute of Pathology 1959.

    Google Scholar 

  • Fras, I., Litin, E., Bartholomew, L.G.: Mental symptoms as an aid in the early diagnosis of carcinoma of the pancreas. Gastroenterology 55, 191–198 (1968).

    PubMed  CAS  Google Scholar 

  • Fras, I., Litin, E.M., Pearson, J.S.: Comparision of psychatric symptoms in carcinoma of the pancreas with those in some other intra-abdominal neoplasm. Amer. J. Psychiat. 123, 1553–1562 (1967).

    PubMed  CAS  Google Scholar 

  • Frerichs, H.: Die Leucin-Hypoglykämie. Dtsch. med. Wschr. 90, 960–965 (1965).

    PubMed  CAS  Google Scholar 

  • Freytag, G.: Ein Fall von Pankreascarcinom mit Herzmetastasen. Inaug.-Diss. Med. Kiel, 1929.

    Google Scholar 

  • Friedlander, E.O.: Hyperinsulinism secondary to disease of the pancreas and organs adjacent to the pancreas: a review of the world literature. Ann. intern. Med. 52, 838 (1960).

    PubMed  CAS  Google Scholar 

  • Frileux, Cl., Terquem, J., Wiel, R., Henry, J.-G.: Sur les schwannomes du pancréas (a propos de 2 cas). Arch. Mal. Appar. dig. 51, 721–725 (1962).

    PubMed  CAS  Google Scholar 

  • Friesen, St.R.: A gastric factor in the pathogenesis of the Zollinger-Ellison syndrome. Ann. Surg. 168, 483–501(1968).

    PubMed  CAS  Google Scholar 

  • Friesen, St.R., Bolinger, R.E., Pearse, A.G.E., McGuigan, J.E.: Serum gastrin levels in malignant Zollinger-Ellison syndrome after total gastroectomy and hypophysectomy. Ann. Surg. 172, 504–521(1970).

    PubMed  CAS  Google Scholar 

  • Friesen, St.R., Tracy, H.J., Gregory, R.A.: Mechanism of the gastric hypersecretion in the Zollinger-Ellison syndome: Successful extraction of gastrin-like activity from metastases and primary pancreatico-duodenal islet cell carcinoma. Ann. Surg. 155, 167–174 (1962).

    Google Scholar 

  • Fujita, T.: The identification of the argyrophil cells of pancreatic islets with D-cells. Arch. histol. jap. 25, 189–197 (1964).

    PubMed  CAS  Google Scholar 

  • Fujita, T.: D-cell, the third endocrine element of the pancreatic islet. Arch. histol. jap. 29, 1–40 (1968).

    PubMed  CAS  Google Scholar 

  • Ganguli, P.C., Polak, J.M., Pearse, A.G.E., Elder,J.B., Hegarty, M.: Antral-gastrin cell hyperplasia in peptic ulcer diseasea new clinical entity. Lancet 1974 I, 583–586.

    Google Scholar 

  • Garland, H.: Endogenous hypoglycaemia. Proc. roy. Soc. Med. 51, 979 (1958).

    PubMed  CAS  Google Scholar 

  • Gelder, A. van Houtenm, H. van, Ronnen, J.R. v., Heul, R.O. van der: Diarree en maagzuurpro-duktie, en het syndroom van Zollinger en Ellison. Ned. T. Geneesk. 111, 15–19 (1967).

    PubMed  Google Scholar 

  • Gepts, W., Desneux, J.J., Henrotin, E.: Tumeur insulaire à cellules argento-réductrices (carcinoides). Acta gastro-ent. belg. 23, 162 (1959).

    Google Scholar 

  • Gerber, B.C., Shields, T.W.: Simultaneous duodenal carcinoid and non-beta cell tumors of the pancreas. Two tumors of high ulcerogenic potential. Arch. Surg. 81, 379 (1960).

    CAS  Google Scholar 

  • Géraud, J., Pasquié, M., Rascol, A., Benazet, J., Juskiewenski, S.: Adénomes Langerhansiens hypoglycémiants chez un enfant de 12 ans. Ann. Chir. infant. 7, 39–48 (1966).

    PubMed  Google Scholar 

  • Gerstel, G.: Über multiple Tumoren der Drüsen mit innerer Sekretion bei einem Akromegalen. Frankfurt. Z. Path. 52, 485–499 (1938).

    Google Scholar 

  • Glenner, G.G., Mallory, G.K.: The cystadenoma and related non-functional tumors of the pancreas. Pathogenesis, classification, and significance. Cancer (Philad.) 9, 980–996 (1956).

    CAS  Google Scholar 

  • Gloor, F., Plëtscher, A., Hardmeier, Th.: Metastasierendes Inseladenom des Pankreas mit 5-Hydroxytryptamin- und Insulinproduktion. Schweiz, med. Wschr. 94, 1476 (1964).

    CAS  Google Scholar 

  • Go, V.L., Poley, J.R., Hofmann, A.F., Summerskill, W.H.J.: Disturbances in fat digestion induced by acidic jejunal pH due to gastric hypersecretion in man. Gastroenterology 58, 638–646 (1970).

    PubMed  CAS  Google Scholar 

  • Goldfarb, W.B., Benett, D., Monafo, W.: Carcinom in heterotopic gastric pancreas. Ann. Surg. 158, 56–58 (1963).

    PubMed  CAS  Google Scholar 

  • Gondard, M.L.: Tumeurs insulaires du pancréas non insulinogénes et syndrome de Zollinger-Ellison d’aprês 61 observations. Arch. Mal. Appar. dig. 49, 1217 (1960).

    PubMed  CAS  Google Scholar 

  • Goodman, J.M.: Duodenal submucosal islet cell adenoma and chronic gastroduodenitis. Amer. J. Surg. 108,726(1964).

    PubMed  CAS  Google Scholar 

  • Goodrick, W.I.M., Dockerty, M.B.: Zollinger-Ellison syndrome, associated gastric tumor showing islet-cell features. Minn. Med. 46, 634–639 (1963).

    PubMed  CAS  Google Scholar 

  • Gordon, L., Chang, M., Schwartz, M.: Carcinoid of the pancreas. Amer. J. 51, 412–415 (1970).

    Google Scholar 

  • Gore, I.: Thrombosis and pancreatic carcinoma. Amer. J. Path. 29, 1093 (1953).

    PubMed  CAS  Google Scholar 

  • Gorski, T.: Cancer of pancreas in mice produced by the combined effects of methylcholanthrene and cortisone. Bl. Acad. pol. Sci., Sér. Sci. biol. 7, 101 (1959).

    Google Scholar 

  • Goulon, M., Rapin, M., Charleux, H., Baguet, J.-G., Kuntzinger, FL, Nouailhat, F., Barois, A., Breteau, M.: Diarrhée aqueuse et hypokaliémie associées a une tumeur Langerhansienne non insulino-sécrétante. Presse méd. 74, 2345–2350 (1966).

    PubMed  CAS  Google Scholar 

  • Graciansky, P. de, Paraf, A., Rautureau, J., Texier, J.: Panniculite nodulaire aiguë fébrile récidivante au cour d’un cancer «Acineux» du pancréas. Le probléme de la maladie de Weber-Christian. Bull. Soc. méd. Hôp. Paris 116, 261–282 (1965).

    Google Scholar 

  • Green, R.C., Jr.: Diabetes mellitus secondary to primary carcinoma of the head of the pancreas. Sth. med. J. (Bgham, Aa.) 52, 1211–1213 (1959).

    Google Scholar 

  • Green, R.C., Baggenstoss, A.H., Sprague, R.G.: Diabetes mellitus in Association with primary Carcinoma of the Pancreas. Diabetes 7, 308 (1958).

    PubMed  Google Scholar 

  • Gregory, R.A.: Secretory mechanism of the gastrointestinal tract. London: Edward Arnold Ltd. 1961.

    Google Scholar 

  • Gregory, R.A., Grossman, M.I., Tracy, H.J., Bentley, P.-H.: Nature of the gastric secretagogue in Zollinger-Ellison tumours. Lancet 1967 II, 543–544.

    Google Scholar 

  • Gregory, H., Hardy, P.M., Jones, D.S., Kenner, G.W., Sheppard, R.C.: The antral hormone gastrin. Nature (Lond.) 204, 931 (1964).

    CAS  Google Scholar 

  • Gregory, H., Hardy, P.M., Jones, D.S., Kenner, G.W., Sheppard, R.C.: Structure of gastrin. Nature (Lond.) 204, 931–933 (1964).

    CAS  Google Scholar 

  • Gregory, R.A., French, H.J., Sircus, E.: Extraction of a gastrin-like substance from pancreatic tumour in a case of Zollinger-Ellison syndrome. Lancet 1960I, 1045.

    Google Scholar 

  • Gregory, R.A., Tracy, H.J.: The constitution and properties of two gastrins extracted from dog antral mucosa. Gut 5, 103–114 (1964).

    PubMed  CAS  Google Scholar 

  • Gregory, R.A., Tracy, H.J.: Isolation of two “big gastrins” from Zollinger-Ellison tumour tissue. Lancet 1972II, 797–799.

    Google Scholar 

  • Gregory, R.A., Tracy, H.J.: A note on the nature gastrin-like stimulant present in Zollinger- Ellison-tumors. Gut 5, 115 (1964).

    PubMed  CAS  Google Scholar 

  • Gregory, R.A., Tracy, H.J., Agarwal, K.L., Grossman, M.L.: Aminoacid constitution of two gastrins isolated from Zollinger-Ellison tumour tissue. Gut 10, 603–608 (1969).

    PubMed  CAS  Google Scholar 

  • Greider, M.H., McGuigan, J.E.: Cellular localization of gastrin in the human pancreas. Diabetes 20, 389–396(1971).

    CAS  Google Scholar 

  • Griebsch, G.: Pankreaskopfadenom mit Pankreasschwanz. Zbl. allg. Path. path. Anat. 115, 511–516 (1972).

    CAS  Google Scholar 

  • Griem, W.: Über einen Fall von Pankreaskarziom bei der Ratte. Berl.-Münch. tierärztl. Wschr. 70, 451–452 (1957).

    Google Scholar 

  • Groezinger, K.H., Dallenbach, F., Heisler, H.: Korrelation zwischen chronischen und malignen Pankreaserkrankungen. Langenbecks Arch. klin. Chir. 325, 47–61(1969).

    Google Scholar 

  • Grosfeld, J.L., Clatworthy, H.W., Hamoidi, A.B.: Pancreatic malignancy in children. Arch. Surg. 101, 370–375 (1970).

    PubMed  CAS  Google Scholar 

  • Gross, F.: Über einen Fall von kleincystischem Adenom des Pankreas. Frankfurt. Z. Path. 53, 320–325 (1939).

    Google Scholar 

  • Grossman, M.: Gastrin. Ucla Forum in Medical Sciences, No. 5. Berkeley and Los Angeles: University of California Press 1966.

    Google Scholar 

  • Grossman, M.L.: Gastrin. Z. Gastroent. 6, 159–162 (1968).

    CAS  Google Scholar 

  • Grossman, M.I.: Gastrin and its activities. Nature (Lond.) 228, 1147–1150 (1970).

    CAS  Google Scholar 

  • Grossman, M.I.: Physiology and pathophysiology of gastrin. Clinics in Gastroent. 3, 533–538 (1974b).

    CAS  Google Scholar 

  • Grossman, M.I., Tracy, H.J., Gregory, R.A.: Zollinger-Ellison syndrome in a Bantu woman, with isolation of a gastrin-like substance from the primary and secondary tumors. II. Extraction of gastrin-like activity from tumors. Gastroenterology 41, 87 (1961).

    PubMed  CAS  Google Scholar 

  • Grossman, M.I. and others: Candidate hormones of the gut. Gastroenterology 67, 730–755 (1974a).

    PubMed  CAS  Google Scholar 

  • Gruber, G.B.: Pathologie der Bauchspeicheldrüse (mit Ausnahme der Langerhansschen Inseln und der Diabetesfrage). Henke-Lubarsch, Handbuch der speziellen pathologischen Anatomie und Histologie, Bd. V2, S. 211 (1929).

    Google Scholar 

  • Grundner, H.G., Böhm, N., Mittermayer, C., Wagner, E., Schultis, K., Nägele, E.: Multiple endokrine Hyperplasien und Adenome mit Zollinger-Ellison-Syndrom und allgemeiner Thromboseneigung. Dtsch. med. Wschr. 94, 375 (1969).

    PubMed  CAS  Google Scholar 

  • Gullick, H.D.: Carcinoma of the pancreas. A review and critical study of 100 cases. Medicine (Baltimore) 38, 47–84 (1959).

    CAS  Google Scholar 

  • Gwynne, J.F., Wilson, S.L.: Cystadenocarcinoma of the pancreas. Aust. N. Z. J. Surg. 26, 315 (1957).

    PubMed  CAS  Google Scholar 

  • Hallenbeck, G.A., Code, Ch.F., Kennedy, J.C.: Effects of extracts of primary and metastatic pancreatic islet cell tumors on gastric secretion: Gastroenterology 44, 631–636 (1963).

    PubMed  CAS  Google Scholar 

  • Hallwright, G.P., North, K.A.K., Reid, J.D.: Pigmentation and Cushing’s syndrome due to malignant tumor of the pancreas. J. clin. Endocr. 24, 496–500 (1964).

    PubMed  CAS  Google Scholar 

  • Hansen, J.R.: Islet cell carcinoma of the pancreas. Ann. Surg. 155, 518–522 (1962).

    PubMed  CAS  Google Scholar 

  • Hansky, J.: Pathophysiology of gastrin. In: Endocrinology of the gut. Hrsg. W.Y. Chey U. F.B. Brooks, p. 304–309. Thorofare/New Yersey: Ch.B. Slack, Inc. 1974.

    Google Scholar 

  • Harris, S.: Hyperinsulinism and dysinsulinism. J. Amer. med. Ass. 83, 729–733 (1924).

    Google Scholar 

  • Hartmann, G., Göring, G.: Benignes Adenom des Pankreaskopfes bei einem Kind. Zbl. Chir. 93, 1687–1692 (1968).

    PubMed  CAS  Google Scholar 

  • Hartsock, R., Fisher, E.R.: Cancer in situ in pancreatic squamous metaplasia. Arch. Surg. 82, 674–678 (1961).

    PubMed  CAS  Google Scholar 

  • Haunz, E.A., Baggenstoss, A.H.: Carcinoma of the head of the pancreas. The effects of obstruction on the ductal and acinar systems. Arch. Path. 49, 367 (1949).

    Google Scholar 

  • Hegler, C., Wohlwill, F.: Fettgewebsnekrosen in Subcutis und Knochenmark durch Metastasen eines Carcinoms des Pankreasschwanzes. Virchows Arch. path. Anat. 274, 784 (1930).

    Google Scholar 

  • Heitz, Ph., Steiner, H., Halter, F., Egli, F., Kapp, J.P.: Multihormonal, amyloid-producing tumour of the islets of Langerhans in a twelve year old boy. Virchows Arch. Abt. A 353, 312–324 (1971).

    CAS  Google Scholar 

  • Henning, K., Franke, D., Redecker, K.: Das isolierte Pankreasneurinom. Fortschr. Med. 86, 127–129(1968).

    Google Scholar 

  • Herfort K.: Klinische Manifestation der Erkrankungen des exokrinen Pankreas. In: Boecker, W., Pankreas-Diabetes. III. Bad Mergentheimer Stoffwechseltagung 1964. Stuttgart: G. Thieme 1965.

    Google Scholar 

  • Herrington, J.: A teenage boy with the Zollinger-Ellison-syndrome presenting multiple ulcerations including perforation of a colonic ulcer. Surgery 58, 442 (1965).

    PubMed  Google Scholar 

  • Herzog, W., Müller, W.: Metastasierendes Adenom des Pankreasinselzellapparates mit weiteren endokrinen Anomalien. Ärztl. Prax. 16, 1444–1446 (1964).

    Google Scholar 

  • Herxheimer, G.: Über eine eigentümliche Veränderung des Pankreas. Verh. Path. Ges. 7, 215 (1904).

    Google Scholar 

  • Herxheimer, G.: Über heterologe Cancroide. Zieglers Beitr. path. Anat. 41, 348 (1907).

    Google Scholar 

  • Hess, W.: Chirurgie des Pankreas. Basel: Benno Schwabe 1950.

    Google Scholar 

  • Hess, W.: Diarrhoen mit Hypokaliämie, Praediabetes und Subacidität, ein neues Syndrom bei Überfunktion des Inselapparates. Helv. chir. Acta 35, 87–90 (1968).

    PubMed  CAS  Google Scholar 

  • Hess, W.: Die chronische Pankreatitis. Klinik, Diagnostik und chirurgische Therapie der chronischen Pankreopathien. Aktuelle Probleme in der Chirurgie 6. Bern u. Stuttgart: Hans Huber 1969.

    Google Scholar 

  • Heyden, S.: Klinische Epidemiologie des Krebses. Stuttgart: Gg. Thieme 1972.

    Google Scholar 

  • Hill, D.M.: Pluriglandular syndrome: Multiple endocrine neoplasia. Proc. roy. Soc. Med. 60, 650–651(1967).

    Google Scholar 

  • Hjärre, A.: Sektionsbefunde beim Diabetes mellitus des Hundes und der Katze. Arch. Tierheilk. 57, 1 (1928).

    Google Scholar 

  • Holub, G., Fischer, M.: Verbrauchskoagulopathie bei Pankreaskarzinom. Med. Welt 23, 370–373 (1972).

    PubMed  CAS  Google Scholar 

  • Howard, E.J.: Phlegmasia cerulea dolens secondary to carcinoma of the pancreas. Angiology 11, 319–322(1960).

    PubMed  CAS  Google Scholar 

  • Howard, J.M.: Pancreatico-duodenectomy: Forty-one consecutive Whipple resections without an operative mortality. Ann. Surg. 168, 629–640 (1968).

    PubMed  CAS  Google Scholar 

  • Howard, J.M., Jordan, G.L.: Surgical disease of pancreas. London: Pitman Medical Publ. Lts. 1960.

    Google Scholar 

  • Hughes, E.S.R., Brown, G.: Carcinoma of the pancreas. . Med. J. Aust. 47, II, 7 (1960).

    PubMed  Google Scholar 

  • Huslarova, A., Niederle, B., Rauchenberg, M.: Das Syndrom von Zollinger-Ellison mit inkompletter Symptomatik. Z. Gastroent. 5, 228–233 (1967).

    Google Scholar 

  • Isenberg, J.I., Walsh, J.H., Grossman, M.I.: Zollinger-Ellison syndrome. Gastroenterology 65, 140–165 (1973).

    PubMed  CAS  Google Scholar 

  • Isenberg, J.I., Walsh, J.H., Passaro, E., Jr.: Unusual effect of secretin on serum gastrin, serum calcium, and gastric acid secretion in a patient with suspected Zollinger-Ellison syndrome. Gastroenterology 62, 626–631 (1972).

    PubMed  CAS  Google Scholar 

  • Iversen, H.G., Johansen, A.: Cystadenocarcinoma pancreatis. (Cystisches Adenocarcinom des Pankreas.) Acta chir. scand. 131, 381–386 (1966).

    CAS  Google Scholar 

  • Ingram, P.W.: Multiple adenoma syndrome. Proc. roy. Soc. Med. 57, 1126–1127 (1964).

    PubMed  CAS  Google Scholar 

  • Jackson, R.H., Blair, E.L., Dawson, P.J., Reed, J.D., Watts, W.P.T.: Gastrin activity of tumour tissue in a child with the Zollinger-Ellison syndrome. Lancet 1963II, 63, 908–912.

    Google Scholar 

  • Jacobs, W.H., Halperin, Ph., Mantz, F.A.: Watery diarrhea and hypokalemia due to nonbeta-islet cell hyperplasia of the pancreas. Amer. J. Gastroent. 57, 333–340 (1972).

    PubMed  CAS  Google Scholar 

  • Janowitz, H.D., Crohn, B.B.: Hyperinsulinism and duodenal ulcer. Gastroenterology 578–580 (1951).

    Google Scholar 

  • Jansen, H.H., Nedden, R.: Klinische Diagnose aus pathologisch-anatomischer Sicht. Der Nutzen der Leichenöffnung für die klinische Medizin. Hess. Ärztebl. 7 (1972).

    Google Scholar 

  • Jansen, H.H., Rothemund, E.: Stenosierende Nebenpankreas mit tödlichem Invaginationsileus bei einem Säugling. Chirurg 36, 518–520 (1965).

    PubMed  CAS  Google Scholar 

  • Jelinek, R., Zischka-Konorsa, W.: Ein Neurom des Pankreas als seltene Ursache einer Melaena. Zbl. Chir. 87, 552–555 (1962).

    Google Scholar 

  • Jiran, B., Telecky, I.: Papilläres Zystadenocarcinom des Pankreasschwanzes. Zbl. Chir. 86, 1399 (1961).

    PubMed  CAS  Google Scholar 

  • Joest, E.: Spezielle pathologische Anatomie der Haustiere, Bd. II, S. 293. Berlin 1921.

    Google Scholar 

  • Johnson, G.J., Summerskill, W.H.J., Anderson, V.E., Keating, F.R., Jr.: Clinical and genetic investigation of a large kindred with multiple endocrine adenomatosis. New Engl. J. Med. 277, 1379–1385(1967).

    PubMed  CAS  Google Scholar 

  • Johnson, J.R., Zintel, H.A.: Pancreatic calcification and cancer of the pancreas. Surg. Gynec. Obstet. 117, 585–588 (1963).

    PubMed  CAS  Google Scholar 

  • Kahlau, G.: Über schwere Hypertonie durch Phaeochromocytom einer Nebenniere mit Adenomen in anderen innersekretorischen Drüsen. Frankfurt. Z. Path. 50, 86–99 (1937).

    Google Scholar 

  • Kalbfleisch, H.H.: Adenome inkretorischer Drüsen bei Hypoglykämie. Frankfurt. Z. Path. 50, 462–477 (1937).

    Google Scholar 

  • Kaye, M.D., Rhoder, R., Beck, P.: Gastric secretion in duodenal ulcer, with particular reference to the diagnosis of Zollinger-Ellison syndrome. Gastroenterology 58, 476–481 (1970).

    PubMed  CAS  Google Scholar 

  • Kerkhoven, P., Halter, F.: Zollinger-Ellison-Syndrom. Schweiz. med. Wschr. 100, 1226–1228 (1970).

    PubMed  CAS  Google Scholar 

  • Kernen, J.A., Poletti, B.J.: Metastatic islet cell carcinoma of the pancreas with long survival. Amer. J. Gastroent. 44, 52–56 (1965).

    PubMed  CAS  Google Scholar 

  • Kernen, J.A., Scofiels, G., Koucky, Ch., Benitez, R.E., Ackerman, L.V.: Long survival with islet cell carcinoma of the pancreas. J. Amer. clin. Path. 39, 137–147 (1963).

    Google Scholar 

  • Kerr, G.D., Smith, R.: Hypercalcaemia and gastric hypersecretion in the familial endocrine-adenoma syndrome. Lancet 1967I, 1074–1077.

    Google Scholar 

  • Kessler, I.I.: Cancer mortality amoung diabetes. J. nat. Cancer Inst. 44, 673–686 (1970).

    PubMed  CAS  Google Scholar 

  • Kirtland, H.B.: A safe method pancreatic biopsy. A preliminary report. Amer. J. Surg. 82, 451–457 (1951).

    Google Scholar 

  • Knappe, G.: Endokrin bedingte Krankheitsbilder bei Inselzelltumoren des Pankreas. Dtsch. med. Wschr. 92, 168–173 (1967).

    PubMed  CAS  Google Scholar 

  • Koch, E., Sailer, F.X.: Mehrjährige Beobachtungen an zwei Totalpankreatektomierten. Dtsch. med. Wschr. 88, 2499–2503,

    Google Scholar 

  • Koch, E., Sailer, F.X.: Mehrjährige Beobachtungen an zwei Totalpankreatektomierten. Dtsch. med. Wschr. 88, u. Bild. 2513 (1963).

    Google Scholar 

  • Koenen-Schmaehling, R., Hartwich, G., Dittrich, H.: Verner-Morrison-Syndrom. Kasuistischer Bericht. Münch. med. Wschr. 112, 98–101 (1970).

    Google Scholar 

  • Klintrup, H.E.: Carcinoma of the pancreas. Acta chir. scand., Suppl. 362 (1966).

    Google Scholar 

  • Kolb, P.: Das Problem der Syntropie von Diabetes und Carcinom. Z. Krebsforsch. 61, 81 (1956).

    PubMed  CAS  Google Scholar 

  • Korman, M.G., Soveny, C., Hansky, J.: Paradoxical effect of secretin on serum immunoreactive gastrin in the Zollinger-Ellison syndrome. Digestion 8, 407–416 (1973).

    PubMed  CAS  Google Scholar 

  • Krain, L.S.: The rising incidence of carcinoma of the pancreas. An epidemiologic appraisal. Amer. J. Gastroent. 54, 500–507 (1970).

    CAS  Google Scholar 

  • Kropff, G., Boeffard, J., Kerneis, J.P., Thuaud, J.: Cystadénome du pancréas traité avec succés par l’exérèse. J. Chir. (Paris) 80, 476–512 (1960).

    CAS  Google Scholar 

  • Kümmerle, F.: Die Chirurgie der duodenopankreatischen Region. Langenbecks Arch. klin. Chir. 313, 218–227(1965).

    Google Scholar 

  • Kümmerle, F.: Probleme der Erkennung und Behandlung maligner Tumoren des Pankreas. In: Pathologie, Biochemie und Therapie der Pankreaserkrankungen. Hrsg. Beck. Stuttgart: Schattauer 1967.

    Google Scholar 

  • Kümmerle, F.: Erkennung und Behandlung maligner Pankreasgeschwülste. In: Pankreaserkrankungen. Hrsg. Schönbach. Stuttgart: Schattauer 1969.

    Google Scholar 

  • Kümmerle, F.: Die spezielle Diagnostik und operative Behandlung des Pankreas- und Papillenkarzinoms. Ärztl. Fortbild. 21, 17–20 (1971).

    Google Scholar 

  • Kümmerle, F.: Maligner Verschlußikterus. Therapiewoche 44, 1–4 (1972).

    Google Scholar 

  • Kümmerle, F., Ehlert, C.P., Nagel, M., Pross, E.: Operative Behandlung der Geschwülste der Gallenblase, der Gallengänge, des Duodenums und des exkretorischen Pankreasanteiles. In: Therapie maligner Tumoren. Hrsg. Holder. Stuttgart: Enke 1967.

    Google Scholar 

  • Larsson, L.I., Ljungberg, O., Sundler, F., Håkanson, R., Svensson, S.O., Rehfeld, J., Stadil, F., Holst, J.: Antropyloric gastrinoma associated with pancreatic nesidioblastosis and proliferation of islets. Virchows Arch. Abt. A 360, 305 (1973).

    CAS  Google Scholar 

  • Laszlo, A. Ormos, J.: Zollinger-Ellison-Syndrom und Pankreas-Zystadenom. Zbl. allg. Path. path. Anat. 110, 12–18(1967).

    Google Scholar 

  • Laurent,J., Debry, G., Floquet, J.: Hypoglycaemic tumours. Amsterdam: Excerpta Medica 1971.

    Google Scholar 

  • Law, D.H., Liddle, G.W., Scott, H.W., Tauber, St.D.: Ectopic production of multiple hormones (ACTH, MSH, and gastrin) by single malignant tumor. New Engl. J. Med. 273, 292–296 (1965).

    PubMed  CAS  Google Scholar 

  • Leffkowitz, M., Landau, B., Boss, J.H.: Insulinoma associated with peptic ulcers. Report of a case. Gastroenterologia (Basel) 93, 157 (1960).

    CAS  Google Scholar 

  • Leger, L., Dupuy, R., Sors, C., Magdelaine, M., Jouan, F., Desgeorgs, H., Mouktar, M., Lemaigre, G.: Hyperplasie adénomateuse du pancréas endocrine, diarrhée et douleurs. Presse méd. 70, 2739–2742 (1962).

    Google Scholar 

  • Leupold, F.: Über bösartige Pankreastumoren mit mehrjährigem Krankheitsverlauf. Ärztl. Wschr. 9, 1135–1139(1954).

    CAS  Google Scholar 

  • Levin, M.E.: Endocrine syndromes associated with pancreatic islet cell tumors. Med. Clin. N. Amer. 52, 295–312 (1968).

    PubMed  CAS  Google Scholar 

  • Li, Fr.P., Fraumeni, J.F., Mantel, N., Miller, R.W.: Cancer mortality among chemists. J. nat. Cancer Inst. 32, 1159–1164 (1969).

    Google Scholar 

  • Ligneris, M.: Über diffuse Lymphosarkomatose des Pankreas. Berl. klin. Wschr. 1916, Nr. 23.

    Google Scholar 

  • Lloyd, P.C.: A case of hypophyseal tumor with associated tumor-like enlargement of the parathyroid and islands of Langerhans. Bull. Johns Hopk. Hosp. 45, 1–14 (1929).

    Google Scholar 

  • Lomsky, R., Langer, F., Vortel, V.: Demonstration of glucagon in islet cell adenomas of the pancreas by immunofluorescent technic. Amer. J. clin. Path. 51, 245–250 (1969).

    CAS  Google Scholar 

  • Lomsky, R., Langer, F., Vortel, V.: Immunohistochemical demonstration of gastrin in mammalian islets of Langerhans. Nature (Lond.) 223, 618–619 (1970).

    Google Scholar 

  • Lopes, V.M., Reis, D.D., Cunha, A.B.: Islet-cell adenoma of the pancreas with reversible watery diarrhea and hypokalemia. WDHA syndrome. Amer. J. Gastroent. 53, 17–35 (1970).

    PubMed  CAS  Google Scholar 

  • Lougheridge, J.S., Neill, D.W., Willis, J.: Zollinger-Ellison syndrome. Report of a case. Brit. J. Surg. 48, 158 (1960).

    Google Scholar 

  • Lowe, W.C., Palmer, E.D.: Carcinoma of the pancreas. An analysis of 100 patients. Amer. J. Gastroent. 47, 412–420 (1967).

    PubMed  CAS  Google Scholar 

  • Lulu, D.J., Corcoran, Andre, M.: Familial endocrine adenomatosis with associated Zollinger-Ellison syndrome. Wermer’s syndrome. Amer. J. Surg. 115, 695–701 (1968).

    PubMed  CAS  Google Scholar 

  • Lund, Fl.: Carcinoma of the pancreas. Acta chir. scand. 134, 461–465 (1968).

    PubMed  CAS  Google Scholar 

  • Lundh, G., Nordenstam, H.: Pancreas calcification and pancreas Cancer. Acta chir. scand. 136, 493–496 (1970).

    PubMed  CAS  Google Scholar 

  • MacMahon, H.E., Brown, P.A., Shen, E.M.: Acinar cell carcinoma of the pancreas with subcutaneous fat necrosis: Gastroenterology 49, 555 (1965).

    PubMed  CAS  Google Scholar 

  • Madsen, B.: Demonstration of pancreatic insulomas by angiography. Brit. J. Radiol. 39, 488–493 (1966).

    PubMed  CAS  Google Scholar 

  • Magnenat, P., Perret, C.: Pankreaskarzinom mit Hyperkalzämie. Gastroenterologia (Basel) 96, 197(1961).

    PubMed  CAS  Google Scholar 

  • Makarész, D.: Familiäres Insulom. Zbl. Chir. 86, 2116 (1961).

    PubMed  Google Scholar 

  • Mallinson, C.N., Salmon, P.R., Borrowman, J., Bloom, S.: The association of a specific skin lesion with islet-cell tumours of the pancreas. Gut 14, 827 (abstr.) (1973).

    PubMed  CAS  Google Scholar 

  • Marek, J.: Klinische Mitteilungen 12. Sarkom des Netzes und des Pankreas beim Hund. Z. Tiermed. 8, 392 (1904).

    Google Scholar 

  • Markert, J.: Zur Problematik des Syndroms multipler endokriner Hyperplasie und Adenome. Zbl. allg. Path. path. Anat. 112, 335–342 (1969).

    CAS  Google Scholar 

  • Markowitz, A.M., Slanetz, Ch.A., Jr., Frantz, V.K.: Functioning islet cell tumors of the pancreas: 25-Year follow up. Ann. Surg. 154, 877–884 (1961).

    PubMed  CAS  Google Scholar 

  • Marks, I.N., Bank, S., Louw, J.H.: Islet cell tumor of the pancreas with reversible watery diarrhes and achlorhydria. Gastroenterology 52, 695–708 (1967).

    PubMed  CAS  Google Scholar 

  • Marks, I.N., Selzer, G., Louw, J.H., Bank, S.: Zollinger-Ellison syndrome in a Bantu woman, with isolation of a gastrin-like substance from the primary and secondary tumors. I. Case report. II. Extraction of gastrin-like activity from tumors. Gastroenterology 41, 77–87 (1961).

    PubMed  CAS  Google Scholar 

  • Marks, V., Marrack, D., Rose, F.C.: Hyperinsulinism in the pathogenesis of neuroglycopenic syndroms. Proc. roy. Soc. Med. (Lond.) 54, 747–749 (1961).

    CAS  Google Scholar 

  • Matsumoto, K.K., Peter, J.B., Raymond, G., Schultze, M.D., Hakim, A.A., Franck, P.T.: Watery diarrhea and hypokalemia associated with pancreat islet-cell adenoma. Gastroenterology 50, 230–242(1966).

    Google Scholar 

  • Matter, H., Marzano, E.: Pankreaszysten. Schweiz, med. Wschr. 91, 1482–1490 (1961).

    CAS  Google Scholar 

  • Maurer, W.A., Walser, Gloor, F.: Hypophysenadenom, Hyperparathyreoidismus und Hyperthyreose. Mitteilung eines Falles von multipler endokriner Adenomatose mit Konsanguinität der Eltern der Patientin. Schweiz. med. Wschr. 96, 536–542 (1966).

    PubMed  CAS  Google Scholar 

  • McBee, J.W., Lanza, F.L., Erickson, E.E.: Hypoglycemia due to obstruction of pancreatic excretory ducts by carcinoma. Arch. Path. 81, 287 (1966).

    PubMed  CAS  Google Scholar 

  • McFarland, J.O., Gillett, F.S., Zwermer, R.J.: Total pancreatectomy for hyperinsulinism in infants. Surgery 57, 313 (1965).

    Google Scholar 

  • McGavran, M.H., Unger, R.H., Recant, L.: The identification of a glucagon secreting alpha cell carcinom of the pancreas. Amer. J. Path. 48, 40A–41A (1966).

    Google Scholar 

  • McGavran, M.H., Unger, R.H., Recant, L., Polk, H.C., Kilo, C., Levin, M.E.: A glucagon-secreting alpha-cell carcinoma of the pancreas. New Engl. J. Med. 274, 1408–1413 (1966).

    PubMed  CAS  Google Scholar 

  • McGuigan, J.E.: The Zollinger-Ellison syndrome and related diseases. In: Sleisenger, M.H., Fordtran, J.S.: Gastrointestinal disease, p. 743–756. Philadelphia-London-Toronto: W.B. Saunders Comp. 1973.

    Google Scholar 

  • McGuigan, J.E.: The gastrointestinal hormones. In: Textbook of endocrinology, 5th edit. Hrsg. R.H. Williams, p. 841–846. Philadelphia-London-Toronto: W.B. Saunders Comp. 1974.

    Google Scholar 

  • McIntosh, H.W., Robertson, H.R., Walters, W., Randall, R.V.: Functioning islet-cell carcinoma of the pancreas with metastases and prolonged survival. Arch. Surg. 80, 1021 (1960).

    Google Scholar 

  • McNeer, G., Ewing, J.H.: Exfoliated pancreatic cancer cells in duodenal drainage. A case report. Cancer (N.Y.) 2, 643–645 (1949).

    CAS  Google Scholar 

  • McRae, J.M., Conn, J.H.: Carcinoid of ampulla of vater. Surgery 46, 902–907 (1959).

    Google Scholar 

  • Menozzi, L., Masetto, I.: Cistadenoma del pancreas in diabetico. G. Clin. med. 37, 1455–1476 (1956).

    PubMed  Google Scholar 

  • Mering, J. v., Minkowski, O.: Diabetes mellitus nach Pankreasexstirpation. Naunyn-Schmiedebergs Arch. exp. Path. Pharmak. 26, 371–387(1890).

    Google Scholar 

  • Metzl, J.: Über Zystadenome des Pankreas. Zbl. Chir. 89, 1310–1314 (1964).

    Google Scholar 

  • Meythaler, FR., Müller, A.: Pancreopathia hypoglycemica. Ärztl. Forsch. 20, 337–350, 467–499, 518–548(1966).

    PubMed  CAS  Google Scholar 

  • Moynan, R.W., Neerhout, R.C., Johnson, Th.S.: Pancreatic carcinoma in childhood. J. Pediat. 65, 711(1965).

    Google Scholar 

  • Müller, P.H., Gmür, J.: Metastasierendes Pankreascarcinom mit Kryoproteinämie, Thrombophlebitis saltans. Lungenembolien und Phlegmasia coerulea dolens. Schweiz, med. Wschr. 99, 682–684 (1968).

    Google Scholar 

  • Mulling, G.T., Caperton, E.M., Jr., Crespin, S.R., Williams, R.C., Jr.: Arthritis and skin lesions resembling erythema nodosum in pancreatic diseases. Ann. intern. Med. 68, 75–87 (1968).

    Google Scholar 

  • Murray, J.S., Paton, R.R., Pope, Ch.E.: Pancreatic tumor associated with flushing and diarrhea. Report of a case. New Engl. J. Med. 264, 436 (1961).

    PubMed  CAS  Google Scholar 

  • Murray-Lyon, I. M., Cassar, J., Coulsen, R., Williams, R., Ganguli, P.C., Edwards,J.E., Taylor, K.W.: Further studies on streptozotocin therapy for a multiple hormone-producing islet cell carcinoma. Gut 12, 717–720 (1971).

    PubMed  CAS  Google Scholar 

  • Myren, J., Petersen, H.: Gastric and pancreatic hypersecretion in Strom-Zollinger-Ellison-syndrome, modern aspects of Zollinger-Ellison-syndrome and gastrin. In: Non-insulin-producing tumors of the pancreas, p. 109–119. Hrsg. L. Demling, u. R. Ottenjann. Stuttgart: Georg Thieme 1969.

    Google Scholar 

  • Neundörfer, B.: Störungen des zentralen und peripheren Nervensystems bei Hyperinsulinismus. Fortschr. Med. 91, 193–194 (1973).

    PubMed  Google Scholar 

  • Nicholls, A.G.: Simple adenoma of the pancreas arising from an island of Langerhans. J. med. Res. 8, 385–395 (1902).

    PubMed  CAS  Google Scholar 

  • Oberhelm, H.A., Jr., Nelsen, Th.S., Dragstedt, L.R.: Peptic ulcer associated with tumors of the pancreas. Arch. Surg. 77, 402 (1958).

    Google Scholar 

  • Oberhelman, H.A.: Excisional therapy for ulcerogenic tumors of the duodenum. Arch. Surg. 104, 447(1972).

    PubMed  Google Scholar 

  • Oberhelman, H.A., Nelson, T.S.: Surgical considerations of the management of ulcerogenic tumors of the pancreas and duodenum. Amer. J. Surg. 108, 132 (1964).

    PubMed  Google Scholar 

  • Olsson, O.: Angiographic diagnosis of an islet cell tumor of the pancreas. Acta chir. scand. 126, 346–351(1963).

    PubMed  CAS  Google Scholar 

  • Onuigbo, W.I.B.: Lung cancer metastasis to the pancreas and its surrounding lymph nodes. Brit. J. Dis. Chest 60, 152–155 (1966).

    PubMed  CAS  Google Scholar 

  • Osborne, M.P., Brown, M.E., LeCompte, Ph.M.: Ulcerogenic non-beta cell pancreatic islet carcinoma. Studies on the extraction and assay of a possible gastric secretagogue. Amer. J. Surg. 100, 48 (1960).

    PubMed  CAS  Google Scholar 

  • Overstreet, A.E., Rupp, J.J.: Functioning islet cell adenoma with a note about leucine sensitivity. Ann. intern. Med. 55, 998 (1961).

    PubMed  CAS  Google Scholar 

  • Pabst, K., Kümmerle, F., Hennekeuser, H.H., Mappes, G.: Beitrag zum Krankheitsbild des Verner-Morrison-Syndrom. Dtsch. med. Wschr. 94, 9–13 (1969).

    PubMed  CAS  Google Scholar 

  • Paloyan, E., Lawrence, A.M., Straus, F.H., II, Paloyan, D., Harper, P.V., Cummings, D.: Alpha cell hyperplasia in calcific pancreatitis associated with hyperparathyroidism. J. Amer. med. Ass. 200, 757–761 (1967).

    CAS  Google Scholar 

  • Passaro, E., Jr., Basso, N., Sanchez, R.E., Gordon, H.E.: Newer studies in the Zollinger-Ellison syndrome. Amer. J. Surg. 120, 138–143 (1970).

    PubMed  Google Scholar 

  • Pataky, Zs., Nagy, L., Popik, E.: Über einen vom Pankreaskopf hervorgehenden primären Argentaf-fintumorfall. Zbl. allg. Path. path. Anat. 99, 442 (1959).

    Google Scholar 

  • Pearse, A.G.E.: The cytochemistry and ultrastructure of polypeptide hormone-producing cells (the APUD series) and the embryologic, physiologic and pathologic implications of the concept. J. Histochem. Cytochem. 17, 303–313 (1969).

    PubMed  CAS  Google Scholar 

  • Peart, W.S., Porter, K.A., Robertson, J.I.S., Sandler, M., Baldock, E.: Carcinoid syndrome due to pancreatic-duct neoplasma secreting 5-hydroxytryptophan and 5-hydroxytryptamine. Lancet 1963I, 239–243.

    Google Scholar 

  • Pender, B.: Islet-cell tumor of pancreas, associated with peptic ulceration. Lancet 1959I, 123.

    Google Scholar 

  • Perrier, C.V.: The Zollinger-Ellison syndrome. Its place in the pathophysiology of gastric acid secretion and of its hormonal regulation. Ergebn. inn. Med. Kinderheilk. N.F. 23, 89–124 (1965).

    CAS  Google Scholar 

  • Pierre-Bourgeois, Rogé, J., Clément, D., Martin, E., Descamps, J.: Syndrome d’hypercorticisme et cancer pancréatique de type langerhansien. Bull. Soc. med. Hop. Paris, Sér. 4, 75, 665–671 (1959).

    CAS  Google Scholar 

  • Piper, Ch.E., ReMine, W.H., Priestley, J.T.: Pancreatic cystadenomata. Report of 20 cases. J. Amer. med. Ass. 180, 648 (1962).

    Google Scholar 

  • Piribauer, J.: Über eine seltene bösartige neurogene Geschwulst in Gegend des Pankreaskopfes. Frankfurt. Z. Path. 68, 349–360 (1957).

    PubMed  CAS  Google Scholar 

  • Planta, F.v.: Nicht-insulinproduzierende Inselzellgeschwulst des Pancreas und Ulcus pepticum (Zollinger-Ellison-Syndrom). Schweiz. med. Wschr. 87, 1272 (1957).

    Google Scholar 

  • Poel, W.E., Yerganian, G.: Adenocarcinoma of the pancreas in diabetes-prone Chinese Hamster. Amer. J. Med. 31, 861 (1961).

    CAS  Google Scholar 

  • Polak, J.M., Bloom, S., Coulling, I., Pearse, A.G.E.: Immunofluorescent localization of enteroglucagon cells in the gastrointestinal tract of the dog. Gut 12, 311–318 (1971).

    PubMed  CAS  Google Scholar 

  • Polak, J.M., Stagg, B., Pearse, A.G.E.: Two types of Zollinger-Ellison syndrome: immunofluorescent, cytochemical and ultrastructural studies on the antral and pancreatic gastrin cells in different clinical states. Gut 13, 501–512 (1972).

    PubMed  CAS  Google Scholar 

  • Poth, E.J., Fromm, St.M.: The relation of pancreatic secretion to peptic ulcer formation. III. The influence of the hyperglycemic-glycogenolytic factor. Gastroenterology 16, 490–494 (1950).

    PubMed  CAS  Google Scholar 

  • Presaud, V., Walrond, E.R.: Carcinoid tumor and cystadenoma of the pancreas. Arch. Path. (Chic.) 92, 28–30(1971).

    Google Scholar 

  • Philipp, P.W.: Über Krebsbildung im Kindesalter. Z. Krebsforsch. 5, 326 (1907).

    Google Scholar 

  • Phillips, S.F., King, W.E.: Carcinoma of the pancreas. Med. J. Aust. 49, 541–545 (1962).

    PubMed  Google Scholar 

  • Priest, W.M., Alexander, M.K.: Islet-cell tumor of the pancreas with peptic ulceration, diarrhoea, and hypokalaemia. Lancet 1957 II, 1145.

    Google Scholar 

  • Raia, S.: Malignant tumors of exocrine pancreas: anatomo-clinical study of 150 cases. Rev. Hosp. Clin. Fac. Med. S. Paulo 18, 1–16 (1963) (Portugiesisch).

    PubMed  CAS  Google Scholar 

  • Rambaud, J.C., Matuchansky, C.: Diarrhoea and digestive endocrine tumors. Clinics in Gastroent. 3, 657–670 (1974).

    Google Scholar 

  • Rambaud, J.C., Mignon, F., Hautefeuille, P., Potet, F., Bognel, C., Modigliani, R., Bourel, M., Bernier,J.J.: Syndrome de Verner-Morrison a forme non tumorale. Rev. méd.-chir. Foie (R.M.F.) 45, 261–269 (1970).

    CAS  Google Scholar 

  • Ranström, S.: Haemangioma cavernosum pancreatis. Zbl. allg. Path. path. Anat. 73, 33–35 (1939).

    Google Scholar 

  • Raskin, H.F., Wenger, J., Sklar, M., Pleticka, S., Yarema, W.: The diagnosis of cancer of the pancreas, biliary tract and duodenum by combined cytologic and secretory methods. I. Exfoliative cytology a description of a rapid method of duodenal intubation. Gastroenterology 34, 996 (1958).

    PubMed  CAS  Google Scholar 

  • Reeder, D.D., Jackson, B.M., Ban, J., Clendinnen, B.G., Davidson, W.D., Thompson, J.C.: Influence of hypercalcemia on gastric secretion and serum gastrin concentration in man. Ann. Surg. 1972, 540–546 (1970).

    Google Scholar 

  • Rehfeld, J.F.: Three components of gastrin in human serum. Biochim. biophys. Acta (Amst.) 285, 364–372(1972).

    CAS  Google Scholar 

  • Rehfeld, J.F., Stadil, F.: “Big gastrins” in the Zollinger-Ellison syndrome. Lancet 1972 II, 1200.

    Google Scholar 

  • Rehfeld, J.F., Stadil, F., Vikelsøe, J.: Immunoreactive gastrin components in human serum. Gut 15, 102–111(1974).

    PubMed  CAS  Google Scholar 

  • Reis, H.E., Kanzler, G., Schulz, P.: Polyendokrine Adenomatose. Dtsch. med. Wschr. 3, 11 (1971).

    Google Scholar 

  • Richard, L., Jr., Cohn, L, Jr.: Cancer of the pancreas. Amer. J. Surg. 35, 95–103 (1969).

    Google Scholar 

  • Richards, W.G!? Katzmann, F.S., Coleman, F.C.: Extramedullary plasmacytom arising in the head of the pancreas. Report of a case. Cancer (Philad.) 11, 649 (1958).

    CAS  Google Scholar 

  • Rockstroh, H., Schröter, H.: Die Häufigkeit des Krebses beim Diabetes mellitus. Münch. med. Wschr. 102, 897 (1960).

    PubMed  CAS  Google Scholar 

  • Rosai, J.: Carcinoma of pancreas simulating giant cell tumor of bone. Electronmicroscopic evidence of its acinar cell origin. Cancer (Philad.) 22, 333–344 (1968).

    CAS  Google Scholar 

  • Rosenbaum, H., Connolly, P.J., Climie, A.R.W., Reveno, W.S.: Pancreatic cystadenoma with intestinal hemorrhage. Amer. J. Roentgenol. 90, 735–739 (1963).

    PubMed  CAS  Google Scholar 

  • Rosenberg, A.A.: Fulminating adrenocortical hyperfunction assiociated with islet cell carcinoma of the pancreas: case report. J. clin. Endocr. 16, 1364–1373 (1956).

    PubMed  CAS  Google Scholar 

  • Rosenlund, M.L.: The Zollinger-Ellison syndrome in children. A Review. Amer. J. med. Sci. 254, 884–892(1967).

    CAS  Google Scholar 

  • Rosenlund, M.L., Crean, G.P., Johnson, D.G., Holtzapple, P.G., Brooks, F.P.: The Zollinger-Ellison syndrome in a 10-year-old boy. J. Pediat. 75, 443–448 (1969).

    PubMed  CAS  Google Scholar 

  • Ross, C.F.: Leiomyosarcoma of the pancreas. Brit. J. Surg. 39, 53–56 (1951).

    PubMed  CAS  Google Scholar 

  • Rossier, P.H., Dressler, M.: Familiäre Erkrankung innersekretorischer Drüsen kombiniert mit Ulkuskrankheit. Schweiz. med. Wschr. 69, 985–990 (1939).

    Google Scholar 

  • Rossmann, P.: Lungenmetastasen des Pankreaskrebses mit klinischem Bild des Alveolarkrebses. Zbl. allg. Path. path. Anat. 99, 301 (1959).

    Google Scholar 

  • Rowe, Ph.: Papillary cystadenocarcinoma of the pancreas. Canad. med. Ass. J. 74, 724 (1956).

    PubMed  CAS  Google Scholar 

  • Rowlatt, U.: Spontaneous epithelial tumours of the pancreas of mammals. Brit. J. Cancer 21, 82–107(1967).

    PubMed  CAS  Google Scholar 

  • Rowlatt, U., Roe, F.J.C.: Epithelial tumors of the rat pancreas. J. nat. Cancer Inst. 39, 17–32 (1967).

    PubMed  CAS  Google Scholar 

  • Royston, C.M.S., Brew, D.S.J., Garnham, J.R., Stagg, B.H., Polak, J.M.: The Zollinger-Ellison syndrome due to an infiltrating tumour of the stomach. Gut 13, 638–642 (1972).

    PubMed  CAS  Google Scholar 

  • Säuberli, H., Largiadèr,F., Vetter, W.: Das Magenantrumhormon Gastrin. I. Teil: Physiologie und radioimmunologische Bestimmung. Schweiz. med. Wschr. 104, 709–713 (1974).

    PubMed  Google Scholar 

  • Säuberli, H., Largiadèr, F., Vetter, W.: Das Magenantrumhormon Gastrin. II. Teil: Die praktische Bedeutung der Gastrinbestimmung bei verschiedenen Krankheiten. Schweiz. med. Wschr. 104, 745–751 (1974).

    PubMed  Google Scholar 

  • Said, S.I., Makhlouf, G.M.: Vasoactive intestinal polypeptide: spectrum of biological activity. In: Endocrinology of the gut, p. 83–87. Hrsg. W.Y. Chey und F.B. Brooks. Thorofare/New Yersey: Ch. B. Slack, Inc. 1974.

    Google Scholar 

  • Said, S.I., Mutt, V.: Isolation from porcine intestinal wall of a vasoactive octacosapeptide related to secretin and to glucagon. Europ. J. Biochem. 28, 199–204 (1973).

    Google Scholar 

  • Sailer, S., Zinninger, M.M.: Massive islet cell tumor of the pancreas without hypoglycemia. Surg. Gynec. Obstet. 82, 301–305 (1946).

    PubMed  CAS  Google Scholar 

  • Salm, R.: Scirrhous adenocarcinoma arising in a lipomatous pseudohypertrophic pancreas. J. Path. Bact. 79, 47 (1960).

    PubMed  CAS  Google Scholar 

  • Salm, R., Path, F.C.: Carcinoma arising in a lipomatous pseudohypertrophic pancreas. Brit. med. J. 1968 III, 293.

    Google Scholar 

  • Salom, P.A.: Carcinoma of the pancreas and extrahepatic biliary system. Surgery 60, 554–565 (1966).

    Google Scholar 

  • Salom, P.A.: The significance of psychic symptoms in the early diagnosis of carcinoma of the pancreas. Canad. med. Ass. J. 97, 767–772 (1967).

    Google Scholar 

  • Salti, LG., Walker, Th.W.: Islet-cell tumors of the pancreas. Arch. Surg. 85, 238–244 (1962).

    PubMed  CAS  Google Scholar 

  • Sanchez, G.C., Sommers, S.C.: Peptic ulcer diathesis with a mixed adenocarcinoma of the pancreas. Case report. Case Reports 38, 467–470 (1959).

    Google Scholar 

  • Schlesinger, F.G., Schwarz, F., Wagenvoort, C.A.: The association of Diabetes mellitus with primary carcinoma of the pancreas. Acta med. scand. 166, 337 (1960).

    PubMed  CAS  Google Scholar 

  • Schlick, U.: Über das Pankreascarcinom. Inaug.-Diss. (med.) Heidelberg, 1969.

    Google Scholar 

  • Schmid, M.: Über das Syndrom des sekretorisch aktiven metastasierenden, exokrinen Pankreasadenoms. Z. klin. Med. 154, 439–455 (1957).

    PubMed  CAS  Google Scholar 

  • Schmid, M., Wenzl, H., Uehlinger, E.: B-Inselzell-Adenom des Pankreas mit Hypoglykämie, kombiniert mit multiplen Karzinoidtumoren des Ileum. Schweiz, med. Wschr. 93, 444–446 (1963).

    Google Scholar 

  • Schönemann, H.: Pluriglanduläre Symptome bei Tetanie. Klin. Wschr. 5, 1137–1139 (1926).

    Google Scholar 

  • Schoenemann, J.: Das Verner-Morrison-Syndrom (pankreatische Cholera). Dtsch. Gesundh.-Wes. 27, 1782–1788 (1972).

    CAS  Google Scholar 

  • Scholz, D.A., ReMine, W.H., Priestley, J.T.: Hyperinsulinism: Review of 95 cases of functioning pancreatic islet cell tumors. Proc. Mayo Clin. 35, 545 (1960).

    CAS  Google Scholar 

  • Seelig, H.-P.: Gastrin und die Theorie seiner Wirkungen. Med. Welt 18, (N.F.) 2275–2281 (1967).

    Google Scholar 

  • Seelig, H.P.: Gastrin. Inaktivierung und Abbau. Gastroenterologie und Stoffwechsel, Bd. 1. Stuttgart: Gg. Thieme 1972.

    Google Scholar 

  • Seelig, H.P.: Gastrin Bildungsstätte, Struktur, Inaktivierung und Abbau. Dtsch. med. Wschr. 3, 87–89 (1972).

    Google Scholar 

  • Segi, M., Kurihara, M.: Geographische Krebsstudien. Ein Vergleich der standardisierten Sterbeziffern. Mitteilungsdienst d. Ges. Bekämpfg. der Krebskrankheiten Nordrhein-Westfalen e.V. III, 69–159(1963).

    Google Scholar 

  • Seifert, G.: Die Pathologie des kindlichen Pankreas. Leipzig: Thieme 1956.

    Google Scholar 

  • Seifert, G., Berdrow, J.: Morphologische Klassifikation der Inseltumoren des Pankreas und endokrine Aktivität. Ärztl. Wschr. 1958, 829–835.

    Google Scholar 

  • Sewing, K.F.: Die physiologische Steuerung der Magen- und Pankreassekretion durch Peptidhormone. Ärztl. Forsch. 23, 223–226 (1969).

    PubMed  CAS  Google Scholar 

  • Shieber, W.: Insulin-producing Zollinger-Ellison tumor. Surgery 54, 448–450 (1963).

    PubMed  CAS  Google Scholar 

  • Shimoda, S.S., Saunders, D.R., Rubin, C.E.: The Zollinger-Ellison syndrome with steatorrhea. II. The mechanism of fat and vitamin B12 malabsorption. Gastroenterology 55, 705–723 (1968).

    PubMed  CAS  Google Scholar 

  • Sieracki, J., Marshall, R., Horn, R.C.: Tumors of the pancreatic islets. Cancer (Philad.) 13, 347–357 (1960).

    CAS  Google Scholar 

  • Siewert, R., Peiper, H.J., Jennewein, H.M., Waldeck, F.: Die Oesophago-Jejunoplicatio. Chirurg 44, 115(1973).

    PubMed  CAS  Google Scholar 

  • Silver, G.B., Lubliner, R.K.: Carcinoma of the pancreas. A clinicopathologic survey. Surg. Gynec. Obstet. 86, 703–716(1948).

    PubMed  CAS  Google Scholar 

  • Singleto, J.W.: Humoral effects of the pancreas upon the gastrointestinal tract. Gastroenterology 56, 342–462 (1969).

    Google Scholar 

  • Singleton, J.W., Kern, F., Waddell, W.R.: Diarrhea and pancreatic islet cell tumor. Report of a case with a severe jejunal mucosal lesion. Gastroenterology 49, 197–208 (1965).

    PubMed  CAS  Google Scholar 

  • Sircus, W.: Evidence for a gastric secretagoue in the circulation and gastric juice of patients with the Zollinger-Ellison-Syndrome. Lancet 1964 II, 671.

    Google Scholar 

  • Sircus, W., Brunt, P.W., Walker, R.J., Small, W.P., Falconer, C.W.A., Thomson, C.G.: Two cases of “pancreatic cholera” with features of peptide-secreting adenomatosis of the pancreas. Gut 11, 197–205 (1970).

    PubMed  CAS  Google Scholar 

  • Skillern, P.G., McCormack, L.J., Hewlett, J.S., Crile,G., Jr.: Hyperinsulinism due to islet-cell tumors simulating sarcoma. A report of two cases of large tumors composed of round and spindle cells associated with hyperglycemia. Diabetes 3, 133 (1954).

    PubMed  CAS  Google Scholar 

  • Slany, J., Wenger, R., Kühlmayer, R.: Multiples primäres Karzinoid der Gallenblase, des Pankreas und des Ileums mit Hefzmetastasen. Z. Gastroent. 7, 213–219 (1969).

    Google Scholar 

  • Sluys Veer, J. van der, Choufoer, C., Querido, A., Heul, R.O. van der, Hollander, C.F., Rijssel, T.G. van: Metastasising islet-cell tumour of the pancreas associated with hypoglycaemia and carcinoid syndrome. Lancet 1964 I, 1416–1419.

    Google Scholar 

  • Slye, M., Holmes, H.F., Wells, H.G.: The comporative pathology of carcinoma of the pancreas, with report of two cases in mice. Amer. J. Cancer 23, 81–85 (1934).

    Google Scholar 

  • Smith, P.E., Krementz, E.T., Reed, R.J., Bufkin, W.J.: An analysis of 600 patients with carcinoma of the pancreas. Surg. Gynec. Obstet. 124, 1288–1290 (1967).

    PubMed  CAS  Google Scholar 

  • Smith, R.: Surgery of pancreatic neoplasm. Edinburgh & London 1953.

    Google Scholar 

  • Sokol, S., Sienkowski, E., Niwinska, Z., Boj, E.: Les neurofibromes du pancréas. Lyon chir. 60, 361–365(1964).

    Google Scholar 

  • Solcia, E., Pearse, A.G.E., Grube, D., Kobayashi, S., Bussolati, G., Creutzfeldt, W., Gept, W.: Revised Wiesbaden classification of gut endocrine cells. Rendiconti Gastroent. 5, 13–16 (1973).

    Google Scholar 

  • Sommers, Sh.C., Meissner, W.A.: Unusual carcinomas of the pancreas. Arch. Path. 58, 101–111 (1954).

    CAS  Google Scholar 

  • Sommers, Sh.C., Murphy, S.A., Warren, Sh.: Pancreatic duct hyperplasia and cancer. Gastroenterology 27, 629 (1954).

    PubMed  CAS  Google Scholar 

  • Spain, D.M.: Minute pancreatic tumor associated with arterial thrombi. Gastroenterology 43, 104–106 (1962).

    PubMed  CAS  Google Scholar 

  • Spencer, H.: Pancreatic islet-cell adenomata. J. Path. 259 (1955).

    Google Scholar 

  • Sproul, E.E.: Carcinoma and venous thrombosis: The frequency of association of carcinoma in the body or tail of the pancreas with multiple venous Thrombosis. Amer. J. Cancer 34, 566 (1938).

    Google Scholar 

  • Stadil, F., Rehfeld, J.F.: Determination of gastrin in serum. Scand. J. Gastroent. 8, 101–112 (1973).

    PubMed  CAS  Google Scholar 

  • Stafford, E.S., Ridgeway Trimble, I., Classen, J.N.: Results of treatment of carcinoma of pancreas. Ann. Surg. 139, 800–805 (1954).

    PubMed  CAS  Google Scholar 

  • Stobbe, H.: Langerhans’sche Inseln im Pankreascarcinom. Z. ges. inn. Med. 9, 917 (1954).

    Google Scholar 

  • Stoker,D.J., Wynn, V.: Pancreatic islets cell tumour with watery diarrhoea and hypokalaemia. Gut 11, 911–920 (1970).

    PubMed  CAS  Google Scholar 

  • Stosiek, P., Rintelen, K.: Semimaligne, funktionell inaktive Pankreasadenome. Med. Klin.62, 1665–1669(1967).

    PubMed  CAS  Google Scholar 

  • Strang, Ch., Walton, J.N.: Carcinoma of body and tail of pancreas. Ann. intern. Med. 39, 15–37 (1953).

    PubMed  CAS  Google Scholar 

  • Straus, E., Yalow, R.S.: Studies on the distribution and degradation of heptadecapeptide, big, and big big gastrin. Gastroenterology 66, 936–943 (1974).

    PubMed  CAS  Google Scholar 

  • Strom, R.: A case of peptic ulcer and insuloma. Acta chir. scand. 104, 252–260 (1953).

    Google Scholar 

  • Summerskill, W.H.J.: Malabsorption and jejunal ulceration due to gastric hypersecretion with pancreatic islet-cell hyperplasia. Lancet 1959 I, 120–123.

    Google Scholar 

  • Summerskill, W.H.J., Code, CF., Hallenbeck, G.A., Priestly, J.T.: Intractable peptic ulcer in hereditary endocrine-ulcer disease: “gastrin” content of endocrine tissue. Proc. Mayo Clin. 36, 611–617(1961).

    CAS  Google Scholar 

  • Swanson, G.E.: A case of cystadenoma of the pancreas studied by selective angiography. Radiology 81, 592–595(1963).

    PubMed  CAS  Google Scholar 

  • Tardini, A., Anversa, P., Bordi, C.: Ultrastructure of multiple pancreatic tumors in a case of Zollinger-Ellison syndrome. Amer. J. clin. Path. 52, 25–36 (1969).

    CAS  Google Scholar 

  • Tayot, J.: Pyléthrombose et cancer du pancréas. Thromboses vasculariés multiples, épithéliomateuses et fibrinocruoriques. Arch. Anat. path. 8, 157 (1960).

    Google Scholar 

  • Terbrüggen, A.: Untersuchungen über Inselapparat und Inseladenome des Pankreas, besonders über die Zelltypen bei Diabetes mellitus und Spontanhypoglykämie. Virchows Arch. path. Anat. 315, 407–460 (1944/48).

    Google Scholar 

  • Thomas, C., Zengerling, W., Noetzel, H.: Neurologische Formen des paraneoplastischen Syndroms. Stuttgart: Schattauer 1972.

    Google Scholar 

  • Thomas, R.L., Robinson, A.E., Johnsrude, LS., Goodrich, J.K., Lester, R.G.: The demonstration of an insulin and gastrin producing pancreatic tumor by angiography and pancreatic scanning. Amer. J. Roentgenol. 104, 646–651 (1958).

    Google Scholar 

  • Thompson, J.C., Hirose, F.M., Lemmi, A.E., Davidson, W.D.: Zollinger-Ellison syndrome in a patient with multiple carcinoid-islet cell tumors of Zollinger-Ellison syndrome in a patient with multiple carcinoid islet cell tumors of the duodenum. Effect of tumor extract on isolated gastri mucosa. Amer. J. Surg. 115, 177–184 (1968).

    PubMed  CAS  Google Scholar 

  • Thompson, J.C., Becker, H.D., Evans,J.C.W., Hjelmquist, U.B.E., Brandt, E.N., Reeder, D.D.: Studies on the catabolism of gastrin. In: Endocrinology of the gut, p. 295–303. Hrsg. W.Y. Chey u. F.B. Brooks, Thorofare/New Yersey: Ch.B. Slack, Inc. 1974.

    Google Scholar 

  • Thompson, J.C., Reeder, D.D., Buchman, H.H., Becker, H.D., Brandt, E.N.: Effect of secretin on circulating gastrin. Ann. Surg. 176, 384–392 (1972b).

    PubMed  CAS  Google Scholar 

  • Thompson, J.C., Reeder, D.D., Bunchman, H.A.: Clinical role of serum gastrin measurements in the Zollinger-Ellison syndrom. Amer. J. Surg. 124, 250–261 (1972a).

    PubMed  CAS  Google Scholar 

  • Titone, M.: Über ungewöhnliche ausgebreitete Fettgewebs- und Gewebsnekrosen bei Pankreaskrebs. Virchows Arch. path. Anat. 297, 416 (1936).

    Google Scholar 

  • Topchiashvili, Z. A.: Changes caused by cancer of the head of the pancreas in complete obstruction of pancreatic ducts. Chirurgija (Mosk.) 35, 26 (1959), mit engl. Zus.fassg.

    CAS  Google Scholar 

  • Tracy, H.J., Gregory, R.A.: Physiological properties of a series of synthetic peptides structurally Related to gastrin I. Nature (Lond.) 204, 935–938 (1964).

    CAS  Google Scholar 

  • Underdahl, L.O., Woolner, L.B., Black, B.M.: Multiple endocrine adenomas: Report of 8 cases in which the parathyroidsm pituitary and pancreatic islets were involved. J. clin. Endocr. 13, 20–47(1953).

    PubMed  CAS  Google Scholar 

  • Underwood, L.E., Jacobs, N.M.: Familial endocrine adenomatosis. A family with hyperinsulinism as the predominant manifestation. Amer. J. Dis. Child. 106, 218–223 (1963).

    PubMed  CAS  Google Scholar 

  • Unger, R.H., Eisentraut, A.M., Lochner, J.V.: Glucagon producing tumors of the islets of Langerhans. J. clin. Invest. 42, 987–988 (1963).

    Google Scholar 

  • Vance, J.E., Stoll, R.W., Kitabchi, A.E.,Buchmann, K.D., Hollander, D., Williams, R.H.: Familial nesidioblastosis as the predominant manifestation of multiple endocrine adenomatosos. Amer. J. Med. 52, 211–227 (1972).

    PubMed  CAS  Google Scholar 

  • Vassallo, G., Solcia, E., Bussolati, G., Polak, J.M., Pearse, A.G.E.: Non-G cell gastrin-producing tumours of the pancreas. Virchows Arch. Abt. B 11, 66–79 (1972).

    CAS  Google Scholar 

  • Verner, J.V., Morrison, A.B.: Non-B islet tumours and the syndrome of watery diarrhoea, hypokalemia and hypochlorhydria. Clinics in Gastroent. 3, 595–608 (1974).

    Google Scholar 

  • Verner, J.W., Morrison, A.B.: Islet cell tumor and a syndrome of refractory watery diarrhea and hypokalemia. Amer. J. Med. 25, 374–380 (1958).

    PubMed  CAS  Google Scholar 

  • Waddell, W.R., Leonsins, A.J., Zuidema, G.D.: Gastric secretory and other laboratory studies on two patients with Zollinger-Ellison syndrome. New Engl. J. Med. 260, 56 (1959).

    PubMed  CAS  Google Scholar 

  • Wallau, F.: Verhältnis des Krebses der Bauchspeicheldrüse zu seinen Absiedlungen. Virchows Arch. path. Anat. 283, 321–324 (1932).

    Google Scholar 

  • Way, L., Goldman, L., Dunphy, J.E.: Zollinger-Ellison syndrome. An analysis of twentyfive cases. Amer. J. Surg. 116, 293–304 (1968).

    PubMed  CAS  Google Scholar 

  • Wegmann, T., Zollinger, H.U., Markoff, N.G.: Zollinger-Ellison-Syndrom mit terminaler letaler Hypoglykämie. Dtsch. med. Wschr. 89, 2223–2227 (1964).

    PubMed  CAS  Google Scholar 

  • Weichert, R.F.: The neural ectodermal origin of the peptide secreting endocrine glands. Amer. J. Med. 49, 232–241 (1970).

    PubMed  CAS  Google Scholar 

  • Weichert, R.F., Reed, R., Creech, O.: Carcinoid-islet cell tumors of the duodenum. Ann. Surg. 165, 660–669 (1967).

    PubMed  CAS  Google Scholar 

  • Weichert, R.F., Roth, L.M., Krementz, E.T., Hewitt, R.L., Drapadas, T.: Carcinoid-islet tumors of the duodenum. Report of 21 cases. Ann. J. Surg. 121, 195–205 (1971).

    Google Scholar 

  • Wermer, P.: Genetics aspects of adenomatosis of endocrine glands. Amer. J. Med. 16, 363–371 (1954).

    PubMed  CAS  Google Scholar 

  • Wermer, P.: Endocrine adenomatosis and peptic ulcer in a large kindred. Inherited multiple tumors and mosaic pleiotropism in man. Amer. J. Med. 35, 205–212 (1963).

    PubMed  CAS  Google Scholar 

  • Wermer, P.: The diagnosis of polyadenomatosis of endocrine glands. Radiol. Clin. N. Amer. 5, 349–354 (1967).

    PubMed  CAS  Google Scholar 

  • Wermer, P.: Multiple endocrine adenomatosis; multiple hormone-producing tumours, a familial syndrome. Clinics in Gastroent. 3, 671–684 (1974).

    Google Scholar 

  • Werner, W.: Diabetes mellitus und Carcinom. Z. Krebsforsch. 60, 399 (1955).

    PubMed  CAS  Google Scholar 

  • Whipple, A.O., Frantz, V.K.: Adenoma of islet cells with hyperinsulinism. Ann. Surg. 101, 1299–1335(1935).

    PubMed  CAS  Google Scholar 

  • White,J.J., Piccone, V.A., McCorriston, J.R.: Insulin secreting islet cell tumors of the pancreas. Arch. Surg. 93, 593–597 (1966).

    PubMed  CAS  Google Scholar 

  • Wilson, S.D., Ellison, E.H.: Total gastric resection in children with the Zollinger-Ellison syndrome. Arch. Surg. 91, 165 (1965).

    Google Scholar 

  • Wilson, S.D., Ellison, E.H.: Survival in patients with the Zollinger-Ellison syndrome, treated by total gastrectomy. Ann. Surg. 111, 787 (1966).

    CAS  Google Scholar 

  • Witte, S.: Erste Erfahrungen mit der Zytodiagnostik des Duodenalinhalts bei exokrinen Pankreaser-krankungen. In: Henning-Heinkel-Schön, Pathogenese, Diagnostik, Klinik und Therapie der Erkrankungen des exokrinen Pankreas. Stuttgart: Schattauer 1964.

    Google Scholar 

  • Witte, S.: Die Zytologie des Duodenalsaftes. Dtsch. med. Wschr. 91, 548–549 (1966).

    Google Scholar 

  • Wolff, G.: Hypoglykämie, Med. Mschr. H. 6, 351–355 (1953).

    Google Scholar 

  • Wolff, G.: Hypoglykämie — Literatur-Übersicht 1958–1960. Med. Mschr. 15, 240–377 (1961).

    Google Scholar 

  • Wolff, G.: Hypoglykämie. Pathophysiologie und Diagnose. Med. Mschr. 18, 204–208, 295–300 (1964);

    PubMed  CAS  Google Scholar 

  • Wolff, G.: Hypoglykämie. Pathophysiologie und Diagnose. Med. Mschr. 19, 14–20 (1965).

    PubMed  CAS  Google Scholar 

  • Wolff, G.: Hypoglykämie. Med. Wschr. I, 11–121 (1968).

    Google Scholar 

  • Wolff, G.: Aktuelle Probleme der Hypoglykämie. Med. Welt 22, 1632–1637 (1971).

    Google Scholar 

  • Wuketich, S.: Zollinger-Ellison-Syndrom (Demonstration) . Ges. der Ärzte in Wien, wiss. Sitzung vom 14.2.1958.

    Google Scholar 

  • Wuketich, S., Pavlik, F.: Syndrom des metastasierenden lipasebildenden Pankreasadenoms. Zugleich ein Beitrag zur Differentialdiagnose der Pfeifer-Weber-Christian’schen Krankheit. Arch. klin. exp. Derm. 216, 412–426 (1963).

    PubMed  CAS  Google Scholar 

  • Yalow, R.S.: Heterogeneity of peptide hormones: its implications for radioimmunoassay. In: Radioimmunoassay and related procedures in medicine, vol. I., p. 3–20. Vienna: Internat. Atomic Energy Agency 1974a.

    Google Scholar 

  • Yalow, R.S.: Gastrins. Small, big and big-big. In: Endocrinology of the gut. Hrsg. W.Y. Chey U. F.B. Brooks, p. 261–276. Thorofare/New Yersey: Ch. B. Slack, Inc. 1974b.

    Google Scholar 

  • Yalow, R.S., Berson, S.A.: Radioimmunoassay of gastrin. Gastroenterology 58, 1–14 (1970a).

    PubMed  CAS  Google Scholar 

  • Yalow, R.S., Berson, S.A.: Size and charge distinctions between endogeneous human plasma gastrin in peripheral blood and heptadecapeptide gastrins. Gastroenterology 58, 609–615 (1970b).

    PubMed  CAS  Google Scholar 

  • Yalow, R.S., Berson, S.A.: Further studies on the nature of immunoreactive gastrin in human plasma. Gastroenterology 60, 203–214 (1971).

    PubMed  CAS  Google Scholar 

  • Yalow, R.S., Berson, S.A.: And now “big, big” gastrin. Biochem. biophys. Res. Commun. 48, 391–395(1972).

    PubMed  CAS  Google Scholar 

  • Yoshinaga, T., Okuno, G., Shinji, Y., Tsujii, T., Nishikawa, M.: Pancreatic A-cell tumor associated with severe diabetes mellitus. Diabetes (N.Y.) 15, 709–713 (1966).

    CAS  Google Scholar 

  • Zak, F.G.: Aberrant pancreatic carcinoma in jejunal diverticulum. Gastroenterology 30, 529–533 (1956).

    PubMed  CAS  Google Scholar 

  • Zenker, R., Forell, M.M., Erpenbeck, R.: Zur Kenntnis eines seltenen durch ein Pankreasadenom verursachten Krankheitssyndroms. Dtsch. med. Wschr. 91, 634–638 (1966).

    Google Scholar 

  • Zintl, L.: Pseudovivertikel am Magen durch großes, penetrierendes Pankreaskarzinom. Med. Welt 18, 1632(1967).

    Google Scholar 

  • Zollinger, R.M.: Endocrine adenomas and peptic ulcer, with special reference to pancreatic adenomas. (Symposium.) Gastroenterology 39, 541–543 (1960).

    CAS  Google Scholar 

  • Zollinger, R.M.: Ulcerogenic tumors of the pancreas. Rev. int. Hépat. 16, 649–660 (1966).

    PubMed  CAS  Google Scholar 

  • Zollinger, R.M., Craig, Th.V.: Ulcerogenic tumors of the pancreas. Amer. J. Surg. 99, 424–432 (1960).

    PubMed  CAS  Google Scholar 

  • Zollinger, R.M., Craig, Th.V.: Endocrine tumors and peptic ulcer. Amer. J. 29, 761 (1960).

    CAS  Google Scholar 

  • Zollinger, R.M., Elliott, D.W.: Pancreatic endocrine function and peptic ulceration. Gastroenterology 37, 401 (1959).

    Google Scholar 

  • Zollinger, R.M., Elliott, D.W., Endahl, G.L., Grant, G.N., Goswitz, J.T., Taft, D.A.: Origin of the ulcerogenic hormone in endocrine induced ulcer. Ann. Surg. 156, 570–578 (1962).

    PubMed  CAS  Google Scholar 

  • Zollinger, R.M., Ellison, E.H.: Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas. Ann. Surg. 142, 709 (1955).

    PubMed  CAS  Google Scholar 

  • Zollinger, R.M., Grant, G.N.: Ulcerogenic tumor of the pancreas. J. Amer. med. Ass. 190, 181–184(1964).

    CAS  Google Scholar 

  • Zollinger, R.M., Grant, G.N., Elliott, D.W., Barton, P.: Ulcerogenic tumor of the pancreas. Amer. Surg. 29, 751–755 (1963).

    CAS  Google Scholar 

  • Zollinger, R.M., Tompkins, R.K., Amerson, J.R., Endahl, G.L., Kraft, A.R., Moore, F.T.: Identification of the diarrheogenic hormone associated with non-beta cell tumors of the pancreas. Ann. Surg. 168, 502–521 (1968).

    PubMed  CAS  Google Scholar 

  • Clinical oncology. A manual for students and doctors UICC. Berlin-Heidelberg-New York: Springer 1973.

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1976 Springer-Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

Becker, V., Kümmerle, F., Schier, J., Lenner, V., Londong, W. (1976). Tumoren des Pankreas. In: Beck, K., et al. Pankreas. Handbuch der inneren Medizin, vol 3 / 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66136-5_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-66136-5_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-66137-2

  • Online ISBN: 978-3-642-66136-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics