The cerebral cortex of the embryos treated on day 10 and sacrificed on day 11 of pregnancy is thinner compared to that of control animals. Its inner limiting border has a very irregular shape caused by lumpy protrusions in some sites and marked recesses in others. The lumpy protrusions which were also found in other brain regions and on other days of treatment, appeared ultrastructurally as cytoplasmic protrusions of the inner processes of the ventricular cells lacking organelles. Neither the protrusions and the processes nor the perikarya of the ventricular cells exhibit ultrastructural alterations. These findings are valid not only for the cerebral cortex but in the same way for the brain stem too.


Pigment Epithelium Superior Colliculus Occipital Cortex Ganglion Cell Layer Plexiform Layer 
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Copyright information

© Springer-Verlag Berlin-Heidelberg 1975

Authors and Affiliations

  • Andreas Raedler
    • 1
  • Jobst Sievers
    • 1
  1. 1.Anatomisches InstitutUniversität HamburgHamburg 20Federal Republic of Germany

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