Skip to main content

Effects of Hypercapnia on Pupillary Size, ICP and Cerebral Venous PO2 during Experimental Brain Compression

  • Conference paper
Intracranial Pressure II
  • 116 Accesses

Abstract

When active cerebral vasodilatation occurs during progressive supratentorial brain compression it causes increasingly large rises in ICP. It has been suggested that such episodes of intracranial hypertension produced by vasodilatation may produce neurological deterioration either through cerebral ischaemia consequent on a fall in cerebral perfusion pressure (1) or by promoting tentorial herniation of the brain (2).This investigation was directed towards this problem.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. JENNETT, W.B., BARKER, J., FITCH, W., MCDOWALL, D.G.: The effect of anaesthesia on intracranial pressure in patients with space-occupying lesions. Lancet i, 61–64 (1969).

    Google Scholar 

  2. FITCH, W., MCDOWALL, D.G.: Effect of halothane on intracranial pressure gradients in the presence of intracranial space-occupying lesions. Brit. J. Anaesth. 43, 904–912 (1971).

    Article  PubMed  CAS  Google Scholar 

  3. KETY, S.S., SCHMIDT, C.F.: The effects of altered arterial tensions of carbon dioxide and oxygen on cerebral blood flow and cerebral oxygen consumption of normal young men. J. Clin. Invest. 27, 484–492 (1948).

    Article  CAS  Google Scholar 

  4. REID, W.L., CONE, W.V.: The mechanism of fixed dilatation of the pupil resulting from ipsilateral cerebral compression. J. Amer. Med. Ass. 112, 2030–2034 (1939).

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1975 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Miller, J.D. (1975). Effects of Hypercapnia on Pupillary Size, ICP and Cerebral Venous PO2 during Experimental Brain Compression. In: Lundberg, N., Pontén, U., Brock, M. (eds) Intracranial Pressure II. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66086-3_100

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-66086-3_100

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-66088-7

  • Online ISBN: 978-3-642-66086-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics