Effects of Hypercapnia on Pupillary Size, ICP and Cerebral Venous PO2 during Experimental Brain Compression
When active cerebral vasodilatation occurs during progressive supratentorial brain compression it causes increasingly large rises in ICP. It has been suggested that such episodes of intracranial hypertension produced by vasodilatation may produce neurological deterioration either through cerebral ischaemia consequent on a fall in cerebral perfusion pressure (1) or by promoting tentorial herniation of the brain (2).This investigation was directed towards this problem.
Key wordHypercapnia intracranial pressure brain shift
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