Abstract
Satellite phage P4 is a virus which can only make plaques on E. coli strains which carry P2 or a related helper prophage (Six, 1963; Six and Klug, 1973). P4 requires all the head and tail genes of its helper prophage for
successful lytic multiplication (Six, 1975). As expected from this genetic data, satellite and helper phages appear similar under the electron microscope (Fig. 1; Inman et al., 1971). However, the satellite phage head is smaller than the head of its helper, and contains a smaller genome (m.w. = 7 × 106 daltons, in contrast to 22 × 106 daltons for the P2 helper genome; Inman and Bertani, 1969; Inman et al., 1971). The P2 and P4 genomes are not homologous, since they show ≦ 1% cross-hybridization (Lindqvist, 1974). The small P4 head is never found in cells infected by the helper phage P2 alone. Thus, satellite phage P4 carries the potential for specific head size determination (Gibbs et al., 1973).
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References
Bancroft, J. B., Hiebert, E.: Formation of an infectious nucleoprotein from protein and nucleic acid isolated from a small spherical virus. Virology 32, 354–356 (1967)
Barrett, K., Barclay, S., Calendar, R., Lindqvist, B. H., Six, E. W.: Reciprocal transactivation in a two chromosome phage system. In: Mechanisms of virus disease (C. Fred Fox, ed.). Academic Press 1974, in press
Barrett, K., Calendar, R.: Expression of the satellite phage P4 genome. (1975) In preparation
Bertani, L. E.: Abortive induction of bacteriophage P2. Virology 36, 87–103 (1968)
Bertani, L. E., Bertani, G.: Preparation and characterization of temperate non-inducible bacteriophage P2. J. gen. Virol. 6, 201–212 (1970)
Bijlenga, R. K. L., Scraba, D., Kellenberger, E.: Studies on the morphopoiesis of the head of T-even phage. IX. τ-particles: their morphology, kinetics of appearance and possible precursor function. Virology 56, 250–267 (1973)
Caspar, D. L. D., Klug, A.: Physical principles in the construction of regular viruses. Cold Spr. Harb. Symp. quant. Biol. 27, 1–24 (1962)
Edgar, R. S., Wood, W. B., Jr.: Morphogenesis of bacteriophage T4 in extracts of mutant-infected cells. Proc. nat. Acad. Sci. (Wash.) 55, 498–505 (1966)
Gibbs, W., Goldstein, R. N., Wiener, R., Lindqvist, B., Calendar, R.: Satellite bacteriophage P4: characterization of mutants in two essential genes. Virology 53, 24–39 (1973)
Hohn, T., Hohn, B.: Activity of a head-like structure for in vitro packaging of λ phage DNA. Proc. nat. Acad. Sci. (Wash.) 71, 2372–2376 (1974).
Inman, R. B., Bertani, G.: Heat denaturation of P2 bacteriophage DNA: compositional heterogeneity. J. molec. Biol. 44, 533–549 (1969)
Inman, R. B., Schnös, M., Simon, L. D., Six, E. W., Walker, D. H.: Some morphological properties of P4 bacteriophage and P4 DNA. Virology 44, 67–72 (1971)
Kaiser, A.D., Masuda, T.: In vitro assembly of bacteriophage À heads. Proc. nat. Acad. Sci. (Wash.) 70, 260–264 (1973)
Kellenberger, E., Ryter, A., Sechaud, J.: Electron microscope study of DNA-containing plasma. II. Vegetative and mature phage DNA as compared with normal bacterial nucleosides in different physiological states. J. biophys. biochem. Cytol. 4, 671–678 (1958)
King, J., Laemmli, U.: Bacteriophage T4 tail assembly: structural proteins and their genetic identification. J. molec. Biol. 75, 315–338 (1973)
Laemmli, U. K.: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.) 227, 680–689 (1970)
Laemmli, U.K., Favre, M.: Maturation of the head of bacteriophage T4. I. DNA packaging events. J. molec. Biol. 80, 575–599 (1973)
Lengyel, J. A.: A study of bacteriophage P2 gene products and head morphogenesis. Thesis, University of California, Berkeley (1972)
Lengyel, J., Goldstein, R., Marsh, M., Calendar, R.: Structure and synthesis of the bacteriophage P2 tail. Virology (1974). In press
Lengyel, J. A., Goldstein, R. N., Marsh, M., Sunshine, M. G., Calendar, R.: Bacteriophage P2 head morphogenesis: cleavage of the major capsid protein. Virology 53, 1–23 (1973)
Lindahl, G.: Genetic map of bacteriophage P2. Virology 39, 839–860 (1969)
Lindahl, G.: Bacteriophage P2: replication of the chromosome requires a protein which acts only on the genome that coded for it. Virology 42, 522–533 (1970)
Lindahl, G.: On the control of transcription in bacteriophage P2. Virology 46, 620–633 (1971)
Lindahl, G.: Characterization of bacteriophage P2 conditional-lethal mutants. Molec. gen. Genet. 128, 249–260 (1974)
Lindqvist, B.: Expression of phage transcription in P2 lysogens infected with helper-dependent coliphage P4. Proc. nat. Acad. Sci. (Wash.) 71, 2752–2755 (1974).
Lindqvist, B. H., Bøvre, K.: Asymmetric transcription of the coliphage P2 genome during infection. Virology 49, 690–699 (1972)
Luftig, R. B., Lundh, N. P.: Bacteriophage T4 morphogenesis: isolation, partial characterization and fate of gene 21-defective Tau-particles. Proc. nat. Acad. Sci. (Wash.) 70, 1636–1640 (1973)
Luftig, R., Wood, W. B., Jr., Okinaka, R.: Bacteriophage T4 head morphogenesis. On the nature of gene 49-defective heads and their role as intermediates. J. molec. Biol. 57, 555–573 (1971)
Murray, K., Murray, N. E.: Terminal nucleotide sequences of DNA from temperate coliphages. Nature (Lond.) New Biol. 243, 134–139 (1973)
Padmanabhan, R., Wu, R., Calendar, R.: Base-sequence of the cohesive ends of bacteriophage P2. J. biol. Chem. (1974). In press
Pruss, G., Goldstein, R. N., Calendar, R.: In vitro packaging of satellite phage P4 DNA. Proc. nat. Acad. Sci. (Wash.) 71, 2367–2371 (1974).
Richards, K. E., Williams, R. C., Calendar, R.: Mode of DNA packing within bacteriophage heads. J. molec. Biol. 78, 255–259 (1973)
Six, E. W.: A defective phage depending on phage P2. Bacteriol. Proc., p. 138 (1963)
Six, E. W.: Dependence of bacteriophage P4 on genes of its helper phage, P2. Virology (1975). In press
Six, E. W., Klug, C.: Bacteriophage P4: a satellite virus depending on a helper such as P2. Virology 51, 327–344 (1973)
Six, E. W., Linqvist, B. H.: Multiplication of bacteriophage P4 in the absence of replication of DNA of its helper. Virology 43, 8–15 (1971)
Sunshine, M. B., Thorn, M., Gibbs, W., Calendar, R., Kelly, B.: P2-phage amber mutants: characterization by use of a polarity suppressor. Virology 46, 691–702 (1971)
Thomas, R., Bertani, L. E.: On the control of the replication of temperate bacteriophages superinfecting immune hosts. Virology 24, 241–253 (1964)
Wang, J. C., Martin, K. V., Calendar, R.: On the sequence similarity of the cohesive ends of coliphage P4, P2 and 186 deoxyribonucleic acid. Biochemistry (Wash.) 12, 2119–2123 (1973)
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Goldstein, R., Lengyel, J., Pruss, G., Barrett, K., Calendar, R., Six, E. (1974). Head Size Determination and the Morphogenesis of Satellite Phage P4. In: Arber, W., et al. Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung. Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung, vol 68. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66044-3_3
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DOI: https://doi.org/10.1007/978-3-642-66044-3_3
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