Effects of Dietary Protein on Plasma Cholesterol Levels in Rabbits Fed Cholesterol-Free Semisynthetic Diets
Plasma cholesterol levels increase several fold when rabbits are transferred from commercial diet to cholesterol-free low fat semisynthetic diets (Malmros and Wig-and, 1959; Moore and Williams, 1964; Howard et al., 1965; Carroll, 1971). This increase may be due in part to the casein in the semisynthetic diet, since earlier studies (Meeker and Kesten, 1941) indicated that casein tends to cause a hypercholesterolemia in rabbits and Carroll (1971) observed elevated plasma cholesterol levels in rabbits fed a diet of one part casein and three parts commercial diet. No such increase was observed when dextrose rather than casein was added to the commercial diet. The present experiments were carried out to investigate the effects of feeding proteins from various sources in a low fat cholesterol-free semisynthetic diet and to determine how these effects may be modified by varying the fat and carbohydrate components of the diet.
KeywordsCholesterol Cellulose Starch Corn Hydrate
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