Ēthrane pp 272-279 | Cite as

The Effects of Ēthrane on Intracranial Pressure

  • J. Zattoni
  • C. Siani
  • C. Rivano
Conference paper
Part of the Anaesthesiology and Resuscitation / Anaesthesiologie und Wiederbelebung / Anesthésiologie et Réanimation book series (A+I, volume 84)


In 13 neurosurgical patients artificially ventilated with a N2O-O2 mixture, administration of 1 to 2 % of Ēthrane gene rally induced increases in intracranial pressure. The effect was negligible and sometimes absent in patients with normal intracranial pressure provided PaCO2 was lowered to hypocapnic levels. The effect was often marked, despite hypocapnia, in patients with high intracranial pressure associated with space-occupying cerebral lesions. This dangerous effect could be greatly attenuated if the intracranial fluid content and hence the pressure was previously reduced. The nature of these data as well as the place of the Ēthrane in neurosurgery are discussed.


Cerebral Blood Flow Arterial Blood Pressure Intracranial Pressure Neurosurgical Patient Ethrane Anesthesia 
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Copyright information

© Springer Verlag Berlin Heidelberg 1974

Authors and Affiliations

  • J. Zattoni
  • C. Siani
  • C. Rivano

There are no affiliations available

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