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Immunologische Aspekte des Krebses

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Geschwülste · Tumors I

Part of the book series: Handbuch der allgemeinen Pathologie ((1712,volume 6 / 5))

Zusammenfassung

Das Gebiet der Tumorimmunologie ist in den letzten Jahren rasch gewachsen, da immunologische Methoden auf vielen Gebieten der Krebsforschung angewandt werden. Insbesondere sind sie dazu benutzt worden, Veränderungen in den Tumorzellen selbst nachzuweisen, wie z.B. 1. die Entwicklung neuer antigener Determinanten in Krebszellen und in mit onkogenen Viren infizierten Zellen, 2. den Verlust oder die Verminderung normaler Zellkomponenten und 3. die Synthese löslicher Produkte durch Krebszellen, wie z.B. Myelomproteine. Immunologische Methoden sind aber auch bei der Untersuchung des Krebsträgers angewandt worden, nämlich beim Nachweis spezifischer Immunreaktionen gegenüber wachsenden Tumoren und bei der Untersuchung der Wirkung von Tumoren auf die immunologische Potenz des Tumorträgers.

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  1. Herbert F. Oettgen
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  1. Münster, Germany

    Ekkehard Grundmann

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Oettgen, H.F. (1974). Immunologische Aspekte des Krebses. In: Grundmann, E. (eds) Geschwülste · Tumors I. Handbuch der allgemeinen Pathologie, vol 6 / 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65895-2_9

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