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Interactions of Ionic Mechanisms in the Regulation of the Resistance of Pial Vessels

  • E. Betz
  • H. G. Enzenross
  • V. Vlahov

Abstract

The most convincing arguments for the action of pharmacological, physiological, or pathological stimuli on the smooth muscle cells of brain vessels can be obtained by direct observations of the vascular diameters. To examine the local control mechanisms for the vascular resistance of pial vessels we combined local microperfusion of the extravascular space of small pial arteries and arterioles using mock CSF of various Ca++ and K+ concentrations and varying pH with electrical stimulation of the vessels by tiny electrodes attached directly to the outside of a vessel.

Keywords

Electrical Stimulation Extravascular Space Vascular Diameter Indifferent Electrode Pial Vessel 
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References

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    Knabe, U., and Betz, E.: “The effect of varying extracellular K+, Mg++ and Ca++ on the diameter of pial arterioles.” In: Vascular Smooth Muscle. Berlin: Springer-Verlag (1972).Google Scholar
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    Kuschinsky, W., Wahl, M., Bosse, O., and Thurau, K.: “Perivascular potassium and pH as determinants of local pial arterial diameters in cats.” Circulation Res. 31:240–247 (1972).PubMedGoogle Scholar

Copyright information

© Springer-Verlag New York Inc. 1975

Authors and Affiliations

  • E. Betz
  • H. G. Enzenross
  • V. Vlahov

There are no affiliations available

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