Abstract
The most convincing arguments for the action of pharmacological, physiological, or pathological stimuli on the smooth muscle cells of brain vessels can be obtained by direct observations of the vascular diameters. To examine the local control mechanisms for the vascular resistance of pial vessels we combined local microperfusion of the extravascular space of small pial arteries and arterioles using mock CSF of various Ca++ and K+ concentrations and varying pH with electrical stimulation of the vessels by tiny electrodes attached directly to the outside of a vessel.
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References
Ames, A., Sakauoune, M., and Eudo, S.: “Electrolytes in CSF.” J. Neurophysiol. 27:672–681 (1964).
Axelsson, J., Wahlström, B., Johansson, B., and Jousson, O.: “Influence of the ionic environment on spontaneous electrical and mechanical activity of the rat portal vein.” Circulation Res. 21:609–618 (1967).
Knabe, U., and Betz, E.: “The effect of varying extracellular K+, Mg++ and Ca++ on the diameter of pial arterioles.” In: Vascular Smooth Muscle. Berlin: Springer-Verlag (1972).
Kuschinsky, W., Wahl, M., Bosse, O., and Thurau, K.: “Perivascular potassium and pH as determinants of local pial arterial diameters in cats.” Circulation Res. 31:240–247 (1972).
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© 1975 Springer-Verlag New York Inc.
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Betz, E., Enzenross, H.G., Vlahov, V. (1975). Interactions of Ionic Mechanisms in the Regulation of the Resistance of Pial Vessels. In: Langfitt, T.W., McHenry, L.C., Reivich, M., Wollman, H. (eds) Cerebral Circulation and Metabolism. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65814-3_14
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DOI: https://doi.org/10.1007/978-3-642-65814-3_14
Publisher Name: Springer, Berlin, Heidelberg
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