Circadian Rhythm in Cerebral Blood Volume of Mouse
The superior cervical ganglion appears to be unique among the sympathetic ganglia in that it receives direct information about environmental lighting conditions via a pathway which, in the rat, is well elucidated (12). Accordingly, a diurnal rhythm controlled by light has been demonstrated for norepinephrine in the rat pineal and submaxillary (7) glands which are supplied by postganglionic fibers from these ganglia (1, 4, 9, 10). The superior cervical ganglia also give rise to adrenergic nerves innervating the pial and brain vascular beds (6, 8). Estimation of the overall cerebrovascular response by recording changes in cerebral blood volume (CBV) after sympathetic nerve stimulation and denervation, or after administration of sympathomimetic amines, has revealed a definite adrenergic vasoconstrictor influence on the intracranial vessels (2).
KeywordsDioxide Albumin Cage Norepinephrine Neurol
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