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Functional Aspects of Nucleic Acid Metabolism in Brain

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Central Nervous System

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Abstract

The type of function referred to in this report is concerned largely with the interactions occuring among different classes of cerebral cells in the resting state, in the first instance between neurons and glia. Only brief mention will be made of two experimental approaches related to nervous activity in its more accepted meaning. It is not a novel concept that a concerted metabolic behaviour of the various types of cells in neural tissue may underlie the most complex forms of nervous activity, particularly with regard to the metabolism of macromolecules, but at the present time most of our knowledge in this field stems from microchemical or cytophotometric studies [1,2]. More recently several investigators have studied the biochemistry of cellular fractions from brain, separated in bulk by various procedures, but only in a few cases has the biosynthesis of RNA been studied in these fractions [3,4,5].

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Author information

Authors and Affiliations

  1. International Institute of Genetics and Biophysics, Naples, Italy

    A. Giuditta

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  1. A. Giuditta
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Editor information

Editors and Affiliations

  1. Institute of Pharmacology, University of Turin, Corso Raffaello, 30, I-10125, Turin, Italy

    E. Genazzani

  2. Pharmakologisches Institut, Freien Universität Berlin, D-1000, Berlin 33, Thielallee 69/73, Germany

    H. Herken

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© 1974 Springer-Verlag Berlin · Heidelberg

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Giuditta, A. (1974). Functional Aspects of Nucleic Acid Metabolism in Brain. In: Genazzani, E., Herken, H. (eds) Central Nervous System. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65714-6_8

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  • DOI: https://doi.org/10.1007/978-3-642-65714-6_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-65716-0

  • Online ISBN: 978-3-642-65714-6

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