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Obstructive Uropathy: The Functional Disorder

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Urology in Childhood

Part of the book series: Handbuch der Urologie / Encyclopedia of Urology ((1020,volume 15 / 1))

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Abstract

The need for elimination of obstruction in the urinary tract is so well accepted a principle of urology and surgical procedures for individual obstructions so familiar that it is a matter of surprise that the fundamental nature of the damage to the urinary tract and kidney consequent upon obstruction is not fully understood. Superficially it is abundantly clear that an obstructive lesion produces dilatation of the urinary tract above the obstruction, an increase of pressure within the kidney and an impairment of renal function which is, in the early stages, recoverable. Yet none of these features can be accepted without comment. The presence of dilatation does not necessarily indicate obstruction; the pressure within the apparently obstructed kidney is not always high; the pathology of temporary and permanent renal impairment is still a matter of investigation. Each of these aspects requires discussion from the clinical and experimental point of view, and this chapter is concerned with the upper tract disorder. The criteria for the diagnosis of bladder outflow obstruction are discussed in Chapter 0.

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References

  • Bäcklund, L., Reuterskiöld, A. G.: Activity in the dilated dog ureter. Scand. J. Urol. Nephrol. 3, 99–110 (1969a).

    Article  PubMed  Google Scholar 

  • Bäcklund, L., Reuterskiöld, A. G.: The abnormal ureter in children. Perfusion studies in the wide non-refluxing ureter. Scand. J. Urol. Nephrol. 3, 219–228 (1969b).

    Article  Google Scholar 

  • Barratt, D. M., Chantler, C.: Obstructive uropathy in infants. Proc. roy. Soc. Med. 63, 1248–1250 (1970).

    PubMed  CAS  Google Scholar 

  • Beck, A. D.: Effect of intra-uterine obstruction upon the development of the foetal kidney. J. Urol. (Baltimore) 105, 784–789 (1971).

    CAS  Google Scholar 

  • Bercovitch, D. D., Kasen, L., Blann, L., Levitt, M. F.: The post-obstructive kidney. Observations on nephron function after the relief of 24 hours ureteral ligation in the dog. J. clin. Invest. 50, 1154–1165 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Berlyne, G. M.: Distal tubular function in chronic hydronephrosis. Quart. J. Med. 30, 339–355 (1961).

    PubMed  CAS  Google Scholar 

  • Bernstein, J.: Developmental abnormalities of the renal parenchyma: renal hypoplasia and dysplasia. Pathol. Ann. 3, 213–247 (1968).

    Google Scholar 

  • Bricker, N. S., Shwayri, E. I., Reardan, J. B., Kenog, D., Merrill, J. P., Holmes, J. H.: An abnormality in renal function resulting from urinary tract obstruction. Amer. J. Med. 23, 554–564 (1957).

    Article  PubMed  CAS  Google Scholar 

  • Cannon, P. J., Leeming, J. M., Sommers, S. C., Winters, R. W., Larragh, J. H.: Juxtaglomerular hyperplasia and secondary hyperaldosteronism (Bartter’s syndrome): a re-evaulution of the pathophysiology. Medicine (Baltimore) 47, 107–231 (1968).

    Article  CAS  Google Scholar 

  • Chisholm, G. D.: Obstructive nephropathy. Functional abnormalities and clinical presentations. Proc. roy. Soc. Med. 63, 1242–1245 (1970).

    CAS  Google Scholar 

  • Cussen, L. J.: The structure of the normal human ureter in infancy and childhood. Invest. Urol. 5, 179–194 (1967).

    PubMed  CAS  Google Scholar 

  • Dorhout-Mees, E. J.: Reversible water-losing state caused by incomplete ureteric obstruction. Acta. med. scand. 168, 193–196 (1960).

    Article  PubMed  CAS  Google Scholar 

  • Earley, L. E.: Extreme polyuria in obstructive uropathy. Report of a case of water-losing nephritis in an infant. New Engl. J. Med. 255, 600–605 (1956).

    Article  PubMed  CAS  Google Scholar 

  • Ericsson, N. O., Winberg, J., Zetterstrom, R.: Renal function in infantile obstructive uropathy. Acta, pediat. scand. 44, 444–459 (1955).

    Article  CAS  Google Scholar 

  • Fulop, M., Brazeau, P.: Increased ureteral back pressure enhances tubular sodium re-absorption. J. clin. Invest. 49, 2315–2323 (1970).

    Article  PubMed  CAS  Google Scholar 

  • Ghazali, S., Barratt, T. M.: Sodium excretion after relief of urinary tract obstruction in children. In preparation, 1973.

    Google Scholar 

  • Gibson, A. A. M., Arneil, G. C.: Nephrophthisis. Arch. Dis. Childh. 47, 84–89 (1972).

    Article  PubMed  CAS  Google Scholar 

  • Gottschalk, C. W., Mylle, M.: Micropuncture study of pressures in proximal tubules and peritubular capillaries in the rat kidney and their relation to ureteral and renal venous pressures. Amer. J. Physiol. 185, 430–439 (1956).

    PubMed  CAS  Google Scholar 

  • Hodson, C. J.: Obstructive atrophy of the kidney in children. Ann. Radiol. 10, 273–276 (1967).

    PubMed  CAS  Google Scholar 

  • Holroyd, A. M., Jones, D.: A simple method for obtaining dynamic information from the gamma camera. Phys. in Med. Biol. 14, 631–638 (1969).

    Article  CAS  Google Scholar 

  • Kelsey-Fry, I., Cattell, W. R.: Nephrographic pattern during excretion urography. Brit. med. Bull. 28, 227–232 (1972).

    Google Scholar 

  • Kerr, W. S.: Effects of complete ureteral obstruction in dogs on kidney function. Amer. J. Physiol. 184, 521–526 (1956).

    PubMed  Google Scholar 

  • Kiil, F.: The function of the ureter and renal pelvis. London: Saunders & Co. 1957.

    Google Scholar 

  • Kiil, F., Aukland, K.: Effect of high ureteral pressure on urine concentration during water diuresis. Scand. J. clin. Lab. Invest. 13, 288–275 (1961).

    Article  Google Scholar 

  • Lozzio, B. B.: Hereditary renal disease in a mutant strain of rats. Science 156, 1742–1744 (1967).

    Article  PubMed  CAS  Google Scholar 

  • Maher, J. F., Schreiner, G. E., Waters, T. J.: Osmotic diuresis due to retained urea after release of obstructive uropathy. New Engl. J. Med. 268, 1099–1104 (1963).

    Article  Google Scholar 

  • Manson, A. D., Yalowitz, P. A., Randell, R. V., Greene, L. F.: Dilatation of the urinary tract associated with pituitary and nephrogenic diabetes insipidus. J. Urol. (Baltimore) 103, 327–331 (1970).

    CAS  Google Scholar 

  • Matz, L. R., Craven, J. D., Hodson, C. J.: Experimental obstructive uropathy in the pig. Brit. J. Urol., Suppl. 41, (1969).

    Google Scholar 

  • McCrory, W. W., Shibuya, M., Leumann, E., Karp, R.: Studies of renal function in children with chronic hydronephrosis. Pediat. Clin. N. Amer. 18, 445–466 (1971).

    PubMed  CAS  Google Scholar 

  • Murphy, G. P., Scott, W. W.: The renal haemodynamic response to acute and chronic ureteral obstruction. J. Urol. (Baltimore) 95, 636–657 (1966).

    CAS  Google Scholar 

  • Rose, F., Fraser, G., Friedmann, A., Kohner, E.: Juvenile diabetes mellitus and optic atrophy. Quart. J. Med. 35, 385–405 (1966).

    PubMed  CAS  Google Scholar 

  • Strauthers, N. W.: The role of manometry in the investigation of pelviureteral function. Brit. J. Urol. 41, 129–162 (1969).

    Article  Google Scholar 

  • Suki, W., Eknoyan, G., Rector, F. C., Seldin, D. W.: Patterns of nephron perfusion in acute and chronic hydronephrosis. J. clin. Invest. 45, 122–131 (1966).

    Article  PubMed  CAS  Google Scholar 

  • Teague, N., Boyarsky, S.: Further effects of coliform bacilli on ureteral peristalsis. J. Urol. (Baltimore) 99, 720–724 (1968).

    CAS  Google Scholar 

  • Ten Bensel, R. W., Peters, E. R.: Progressive hydronephrosis, hydro-ureter and dilatation of the bladder in siblings with nephrogenic diabetes insipidus. J. Pediat. 77, 439–443 (1970).

    Article  PubMed  Google Scholar 

  • Vaughan, E. D., Sorensen, E. J., Gillenwater, J. W.: The renal haemodynamic response to chronic unilateral complete obstruction. Invest. Urol. 8, 78–90 (1970).

    PubMed  Google Scholar 

  • Wax, S. H.: Radio-isotope uptake in experimental hydronephrosis. J. Urol. (Baltimore) 99, 497–505 (1968).

    CAS  Google Scholar 

  • Whitaker, R. H.: Methods of diagnosing obstruction in ureters. Brit. J. Urol. (In press) (1973).

    Google Scholar 

  • Winberg, J.: Renal function in water-losing syndrome due to lower urinary tract obstruction before and after treatment. Acta, paediat. scand. 48, 149–163 (1959).

    CAS  Google Scholar 

Download references

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© 1974 Springer-Verlag Berlin Heidelberg

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Williams, D.I., Barratt, T.M. (1974). Obstructive Uropathy: The Functional Disorder. In: Urology in Childhood. Handbuch der Urologie / Encyclopedia of Urology, vol 15 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65687-3_13

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  • DOI: https://doi.org/10.1007/978-3-642-65687-3_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-65689-7

  • Online ISBN: 978-3-642-65687-3

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