Corpuscles pp 65-70 | Cite as

Spherocytes and Knizocytes

  • Marcel Bessis


“Spherocytes” is an historical term. The cells it describes are actually not spheres. They include a variety of cells which are etiologically and morphologically dissimilar. They have only one thing in common: an increase in their thickness. At present, we can distinguish: I. macro-spherocytes produced by osmotic sweIIing of normal erythrocytes; 2. echino-spherocytes (the extreme form of the disco-echinocyte transformation) and stomato-spherocytes (the extreme form of the disco-stomatocyte transformation): in these two types of spherocytes the cell volume is normal; 3. micro-spherocytes resulting from fragmentation; 4. the spherocytes seen in hereditary spherocytosis.


Cell Volume Cell Permeability Cell Physiology Central Depression Extreme Form 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1974

Authors and Affiliations

  • Marcel Bessis
    • 1
    • 2
  1. 1.School of MedicineUniversity of ParisFrance
  2. 2.Institut de Pathologie CellulaireHôpital de BicêtreParisFrance

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