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Angiotensin pp 1–16Cite as

The Biological Production of Angiotensin

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Abstract

The reaction of kidney renin with its plasma substrate to form angiotensin has been studied for many years using both crude and purified materials derived from many species. Much effort has been expended in the attempt to show the existence or efficacy of inhibitors or activators of the reaction. Many enzymological studies have been carried out to determine optimum pH, Michaelis constants, and maximal velocities. Much of the work prior to 1968 has been reviewed in a publication edited by Page and McCubbin (1968).

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Authors
  1. Leonard T. Skeggs
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  2. Frederic E. Dorer
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  3. Joseph R. Kahn
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  4. Kenneth E. Lentz
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  5. Melvin Levine
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Editors and Affiliations

  1. The Cleveland Clinic Foundation, 44106, Cleveland, OH, USA

    Irvine H. Page M.D. (Emeritus Director of Research) (Emeritus Director of Research)

  2. Division of Research, The Cleveland Clinic Foundation, 44106, Cleveland, OH, USA

    F. Merlin Bumpus Ph.D. (Chairman) (Chairman)

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Skeggs, L.T., Dorer, F.E., Kahn, J.R., Lentz, K.E., Levine, M. (1974). The Biological Production of Angiotensin. In: Page, I.H., Bumpus, F.M. (eds) Angiotensin. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology, vol 37. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65600-2_1

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