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Reverse Transcription and the Central Dogma

  • Fred E. Hahn
Chapter
Part of the Progress in Molecular and Subcellular Biology book series (PMSB, volume 3)

Abstract

The Central Dogma of molecular biology which postulates the unidirectional transmission of genetic specifications for protein biosynthesis was enunciated by Crick (1958) who proposed explicitly that “once ‘information’ has passed into protein it cannot get out again. In more detail, the transfer of information from nucleic acid to nucleic acid, or from nucleic acid to protein may be possible, but transfer from protein to protein or from protein to nucleic acid is impossible. Information means here the precise determination of sequence either of bases in the nucleic acids or of amino acids in the protein.”

Keywords

Reverse Transcription Biochemical Evolution Central Dogma Molecular Biologist Rous Sarcoma Virus 
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