Ontogeny of the Immune Response in Cold-Blooded Vertebrates

  • Louis Du Pasquier
Conference paper
Part of the Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung book series (CT MICROBIOLOGY, volume 61)


Most of our present knowledge in immunology has been acquired by studying the immune responses of adult mammals. To understand the ontogenetic differentiation of the immune system of vertebrates, mammals do not appear to be the best model available. Their development is usually fast and interactions between mother and fetus may modify the basic differentiation of the fetal immune system. Moreover it is difficult to work on mammalian embryos in utero. Birds are a good model but their fast development does not leave time to study in detail the immunological responses at embryonary stages.


Xenopus Laevis Graft Rejection Histocompatibility Antigen Larval Life Frog Tadpole 
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© Springer-Verlag, Berlin · Heidelberg 1973

Authors and Affiliations

  • Louis Du Pasquier
    • 1
  1. 1.The Basel Institute for ImmunologyBaselSwitzerland

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