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Steroids and Brain Edema pp 113–121Cite as

Effect of Dexamethasone on Triethyl Tin Induced Brain Edema and the Early Edema in Cerebral Ischemia

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The effects of dexamethasone were investigated in experimental brain edema induced by triethyl tin intoxication and cerebral microembolism. Large doses of steroid (1.25 mg/kg/day) significandy reduced brain water and sodium in triethyl tin poisoned rats. However, in experimental microembolism, steroids had no effect on mortality, severity of edema, brain electrolyte changes, or cerebral isotope spaces.

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Authors and Affiliations

  1. The Edward Mallinckrodt Institute of Radiology, School of Medicine, Washington University, St. Louis, MO, 63110, USA

    Barry A. Siegel, Rebecca K. Studer & E. James Potchen

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  1. Barry A. Siegel
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  2. Rebecca K. Studer
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  3. E. James Potchen
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Editors and Affiliations

  1. Neurochirurgische Universitätsklinik Mainz, 6500, Mainz, Langenbeckstr. 1, W. Germany

    H. J. Reulen  & K. Schürmann  & 

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Siegel, B.A., Studer, R.K., Potchen, E.J. (1972). Effect of Dexamethasone on Triethyl Tin Induced Brain Edema and the Early Edema in Cerebral Ischemia. In: Reulen, H.J., Schürmann, K. (eds) Steroids and Brain Edema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65448-0_12

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  • DOI: https://doi.org/10.1007/978-3-642-65448-0_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-05958-5

  • Online ISBN: 978-3-642-65448-0

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