Effect of Dexamethasone on Triethyl Tin Induced Brain Edema and the Early Edema in Cerebral Ischemia

  • Barry A. Siegel
  • Rebecca K. Studer
  • E. James Potchen


The effects of dexamethasone were investigated in experimental brain edema induced by triethyl tin intoxication and cerebral microembolism. Large doses of steroid (1.25 mg/kg/day) significandy reduced brain water and sodium in triethyl tin poisoned rats. However, in experimental microembolism, steroids had no effect on mortality, severity of edema, brain electrolyte changes, or cerebral isotope spaces.


Cerebral Infarction Brain Edema Cerebral Edema Ischemic Brain Injury Organotin Compound 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1972

Authors and Affiliations

  • Barry A. Siegel
    • 1
  • Rebecca K. Studer
    • 1
  • E. James Potchen
    • 1
  1. 1.The Edward Mallinckrodt Institute of Radiology, School of MedicineWashington UniversitySt. LouisUSA

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