Abstract
Calcium (Ca) metabolism and intestinal Ca absorption have attracted special attention ever since the discovery of vitamin D and the definition of the clinical entities of disturbances of Ca homeostasis in the first three decades of this century. Since then, many details of Ca transport and vitamin D metabolism have accumulated, but only in very recent years have new ideas and findings brought about rapid progress in this field. There is now a startling activity in the investigation of the physiology and pathogenesis of vitamin D and Ca metabolism.
Supported by the Deutsche Forschungsgemeinschaft.
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Albright, F., Bauer, W., Claflin, D., Cockrill, J.R., Aub, J.C.: Studies of parathyroid physiology. III. The effect of phosphate ingestion in clinical hyperparathyroidism. J. clin. Invest. 11, 411–435 (1932).
Albright, F., Bauer, W., Ropes, M., Aub, J.C.: Studies of calcium and phosphorus metabolism. IV. The effect of the parathormone. J. clin. Invest. 7, 139–181 (1929).
Albright, F., Bloomberg, E., Smith, P.H.: Postmenopausal osteoporosis. Trans. Ass. Amer. Phycns 55, 289–305 (1940).
Albright, F., Butler, A.M., Bloomberg, E.: Rickets resistant to vitaminD therapy. Amer. J. Dis. Child. 54, 529–547 (1937).
Albright, F., Henneman, P., Benedict, P.H., Forbes, A.P.: Idiopathic hypercalciuria. J. clin. Endocr. 13, 860–880 (1953).
Anderson, J., Dent, C.E., Harper, C., Philpot, G.R.: Effect of cortisone on calcium metabolism in sarcoidosis with hypercalcemia: possibly antagonistic actions of cortisone and vitamin D. Lancet 1954II, 720–724.
Arman, E., Reizenstein, P.: Studies in the dumping syndrome. IV. Effect of calcium therapy on calcium metabolism and osteopenia in gastrectomized patients. Amer. J. dig. Dis. 14, 153–162 (1969).
Arnaud, C., Maijer, R., Reade, T., Scriver, C.R., Whelan, D.T.: Vitamin D dependency: an inherited postnatal syndrome with secondary hyperparathyroidism. Pediatrics 46, 871–880 (1970).
Arnaud, C., Rasmussen, H., Anast, C.: Further studies on the interrelationship between parathyroid hormone and vitamin D. J. clin. Invest. 45, 1955–1964 (1966).
Atkinson, M., Nordin, B.E.C., Sherlock, S.: Malabsorption and bone disease in prolonged obstructive jaudice. Quart. J. Med. 25, 299–312 (1956).
Au, W.Y.W., Raisz, L.G.: Effect of vitamin D and dietary calcium on parathormone activity. Amer. J. Physiol. 209, 637–642 (1965).
Avioli, L.V.,Birge, S.J., Lee, S.W.: Effects of prednisone on vitamin D metabolism in man. J. clin. Endocr. 28, 1341–1346 (1968b).
Avioli, L.V., Birge, S.J., Slatopolsky, E.: The metabolic fate of vitamin D3–3H in chronic renal failure. J. clin. Invest. 47, 2239–2252 (1968a).
Avioli, L.V., McDonald, J.E., Lee, S.W.: The influence of age in the intestinal absorption of 47 calcium in women and its relation to 47 calcium absorption in postmenopausal osteoporosis. J. clin. Invest. 44, 1960–1967 (1965a).
Avioli, L.V., McDonald, Singer, R.A., Henneman, P.H.: A new oral isotopic test of calcium absorption. J. clin. Invest. 44, 128–139 (1965b).
Avioli, L.V., Scott, S., Lee, S.W.: Intestinal calcium absorption: nature of defect in chronic renal disease. Science 166, 1154–1156 (1969).
Avioli, L.V., Williams, T.F., Lund, J., DeLuca, H.F.: Metabolism of vitamin D3–3H in vitamin D-resistant rickets and familial hypophosphatemia. J. clin. Invest. 46, 1907–1915 (1967).
Badenoch, J., Fourman, P.: Osteomalacia in steatorrhea. Quart. J. Med. 23, 165–176 (1954).
Baer, A., Hurwitz, S.: The accumulation of calcium in laying fowl intestine in vitro. Biochim. biophys. Acta (Amst.) 183, 591–600 (1969).
Baerg, R.D., Kimberg, D.V., Gershon, E.: Effect of renal insufficiency on the active transport of calcium by small intestine. J. clin. Invest. 49, 1288–1300 (1970).
Ball, J., Garner, A.: Mineralization of woven bone in osteomalacia. J. Path. Bact. 91, 563–567 (1966).
Balsan, S.: 25-hydroxycholecalciferol: effects in idiopathic vitamin D-resistant rickets. Calc. Tiss. Res. Suppl. 4, 45–46 (1970).
Bell, N.H.: Comparison of intestinal absorption and esterification of 4-14C vitamin D3 and 4-14C cholesterol in the rat. Proc. Soc. exp. Biol. (N. Y.) 123, 529–532 (1966).
Bell, N.H., Gill, J.R., Bartter, F.C.: On the abnormal calcium absorption in sarcoidosis: evidence for increased sensitivity to vitamin D. Amer. J. Med. 36, 500–513 (1964).
Berger, E.Y.: Techniques for studying ion transfer accross the alimentary tract. In: Wasserman, R.H. (Ed.): The transfer of calcium and strontium accross biological membranes, p. 57. New York-London: Academic Press 1963.
Bersin, T.: Biochemie der Mineral- und Spurenelemente. Akad. Verlagsges. Frankfurt 1963, p. 297.
Berson, S.A., Yalow, R.S.: Parathyroid hormone in plasma in adenomatous hyperparathyroidism, uremia and bronchogenic carcinoma. Science 154, 907–909 (1966).
Berson, S.A., Yalow, R.S., Auerbach, G.D., Potts, J.T.: Immunoassay of bovine and human parathyroid hormone. Proc. nat. Acad. Sci. (Wash.) 49, 613–617 (1963).
Birge, S.J., Kentmann, H.T., Cuatrecasas, P., Whedon, G.D.: Osteoporosis, intestinal lactase deficiency and low dietary calcium intake. New Engl. J. Med. 276, 445–448 (1967).
Blunt, J.W., Tanaka, Y., DeLuca, H.F.: The biological activity of 25-hydroxycholecalciferol, a metabolite of vitamin D. Proc. nat. Acad. Sci. (Wash.) 61, 1503–1506 (1968).
Bogdonoff, M.D., Shock, N.W., Nichols, M.P.: Calcium, phosphorus, nitrogen and potassium balance studies in aged male. J. Geront. 8, 272–288 (1953).
Booth, C.C., Babouris, N., Hanna, S., McIntyre, J.: Incidence of hypermagnesiemia in intestinal malabsorption. Brit. med. J. 1963II, 141–144.
Bordier, P., Matrajt, H., Hicco, D., Hepner, G.W., Thompson, G.R., Booth, C.C.: Subclinical vitamin D deficiency following gastric surgery. Histological evidence in bone. Lancet 1968 1, 437–440.
Bronner, F., Richelle, C.J., Saville, P.D., Nicholas, J.A., Corb, J.R.: Quantitation of calcium metabolism in postmenopausal osteoporosis and in scoliosis. J. clin. Invest. 42, 898–905 (1963).
Bullamore, J.R., Gallagher, J.C., Wilkinson, R., Nordin, B.E.C., Marshall, D.H.: Effect of age on calcium absorption. Lancet 1970II, 535–537.
Burnett, C.H., Commons, R.R., Albright, F., Howard, J.E.: New Engl. J. Med. 240, 787–794 (1945).
Calcium Requirements, Report of an FAO/WHO Expert Group, Rome 1961. Wld. Hlth. Org. Techn. Report Ser. Nr. 301 (1965).
Caniggia, A., Gennari, C., Borello, G., Bencini, M., Cesari, L., Escobar, S.: Intestinal absorption of calcium-47 after treatment with oral oestrogen-gestagens in senile osteoporosis. Brit. med. J. 1970IV, 30–32.
Caniggia, A., Gennari, C., Cesari, L.: Intestinal absorption of 45 calcium and dynamics of 45 calcium in gastrectomy osteoporosis. Acta med. scand. 176, 599–605 (1964).
Cantalamessa, L., Cassi, E., Visca, U.: L’assorbimento intestinal del calcium 47 nei patienti affetti do sarcoidosi. Haematologica 53, 451–463 (1968).
Care, A.D., Sherwood, L.M., Potts, J.T., Auerbach, G.D.: Perfusion of the isolated parathyroid gland of the goat and sheep. Nature (Lond.) 209, 55–57 (1966).
Caspary, W.F.: Inhibition of intestinal calcium transport by diphenylhydantoin in rat duodenum. Naunyn-Schmiedebergs Arch. Pharmacol. (1972); in print.
Clark, C.G., Cooks, J.: Osteomalacia after gastrectomy. Letter to the editor. Lancet 1965II, 1347–1348.
Clark, I., Smith, M.R.: Effect of parathyroidectomy and hydrocortisone on the intestinal absorption of calcium and phosphate. Endocrinology 74, 421–428 (1964).
Clarkson, E.M., McDonald, S.J., DeWardener, H.E.: The effect of high intake of calcium carbonate in normal subjects and patients with renal failure. Clin. Sci. 30, 425–438 (1966).
Comfort, M.W., Wollaeger, E.E., Taylor, A.B., Power, M.H.: Nontropical sprue: observations on absorption and metabolism. Gastroenterology 23, 155–178 (1953).
Condon, J.R., Nassim, J.R., Rutter, A.: Defective intestinal phosphate absorption in familial and nonfamilial hypophosphatemia. Brit. med. J. 1970III, 138–141.
Condon, J.R., Nassim, J.R., Rutter, A.: Pathogenesis of rickets and osteomalacia in familial hypophosphatemia. Arch. Dis. Childh. 46, 269–272 (1971).
Cook, P.B., Nassim, J.R., Collins, J.: The effect of thyreotoxicosis upon metabolism of calcium, phosphorus and nitrogen. Quart. J. Med. 28, 505–529 (1959).
Copp, D.H., Cameron, E.C., Cheney, B., Davidson, A.G.F., Hence, K.G.: Evidence for calcitonin, a new hormone from the parathyroid that lowers blood calcium. Endocrinology 70, 638–649 (1962).
Corradino, R.A., Wasserman, R. H., Pubols, M.H., Chang, S.I.: Vitamin D3 induction of a calcium binding protein in the uterus of the laying hen. Arch. Biochem. 125, 378–380 (1968).
Council on Foods and Nutrition: J. Amer. med. Ass. 185, 588 (1963).
Cramer, C.F.: Participation of parathyroid glands in control of calcium absorption in dogs. Endocrinology 72, 192–196 (1963).
Cramer, C.F.: Sites of calcium absorption and the calcium concentration of gut contents in the dog. Canad. J. Physiol. Pharmacol. 43, 75–78 (1965).
Cramer, C.F., Dueck, J.: In vivo transport of calcium from healed Thiry-Vella fistulas in dogs. Amer. J. Physiol. 202, 161–164 (1962).
Parkes, C.O., Copp, D.H.: The effect of chicken and hog calcitonin on some parameters of calcium, phosphorus and magnesium metabolism in dogs. Canad. J. Physiol. Pharmacol. 47, 181–184 (1969).
Curtis, F.K., Fellows, H., Rich, C.: Estimation of human calcium absorption by external radioisotope counting. J. Lab. clin. Med. 69, 1036–1041 (1967).
Czarnowska-Misztal, E., Zull, J.E., DeLuca, H.F.: Response to vitamin D in adrenalectomized animals. Nature (Lond.) 210, 96–97 (1966).
Dallas, L., Nordin, B.E.C.: The relation between calcium intake and roentgenologic osteoporosis. Amer. J. clin. Nutr. 11, 263–269 (1962).
Davis, G.K.: Interactions of calcium with other nutritients in intestinal absorption. In: Wasserman, R.H. (Ed.): The transfer of calcium and strontium across biological membranes, p. 129. New York-London: Academic Press 1963.
Davis, M.E., Lanzl, L.H., Strandjord, N.M.: Estrogens and the aging process. The detection, prevention and retardation of osteoporosis. J. Amer. med. Ass. 196, 219–224 (1966).
DeGrazia, J.A., Rich, C.: Studies of intestinal absorption of calcium in man. Metabolism 13, 650–660 (1964).
Deller, D.J.: Radiocalcium absorption after partial gastrectomy. Amer. J. dig. Dis. 11, 10–19 (1966).
Deller, D.J., Edwards, R.G., Addison, M.: Calcium metabolism and the bones after partial gastrectomy. II. The nature and cause of the bone disorder. Aus. Ann. Med. 12, 295–309 (1963).
DeLuca, H.F., Lund, J., Rosenbloom, A., Lobeck, C.C.: Metabolism of tritiated vitamin D3 in familial vitamin D-resistant rickets with hypophosphatemia. J. Pediat. 70, 828–832 (1967).
Dent, C.E., Harper, C.M., Philpot, G.R.: The treatment of renal-glomerular osteodystrophy. Quart. J. Med. 30, 1–32 (1961).
Dent, C.E., Watson, L.: Metabolic studies in patients with idiopathic hypercalciuria. Brit. med. J. 1965II, 449–452.
Documenta Geigy: Wissenschaftliche Tabellen, 7. Aufl. Basle/Switzerland: J. R. Geigy S. A. 1968.
Draper, H.H.: The relationship of age and the intestinal absorption of calcium. In: Wasserman, R.H. (Ed.): The transfer of calcium and strontium across biological membranes, p. 97. New York-London: Academic Press 1963.
Drube, H.C., Büttner, H.: Über die Wirkung oraler Kalziumgaben auf die Stuhlfettausscheidung bei Gesunden und Kranken mit Steatorrhoe. Med. Klin. 59, 1234–1236 (1964).
Earp, H.S., Ney, R.L., Gitelman, H. J., Richman, R., DeLuca, H.F.: Effects of 25-hydroxycholecalciferol in patients with familial hypophosphatemia and vitamin D-resistant rickets. New Engl. J. Med. 283, 627–630 (1970).
Ebel, J.G., Taylor, A.N., Wasserman, R.H.: The vitamin D-induced calcium binding protein of intestinal mucosa: relation to vitamin D dose level and the lag period. Amer. J. clin. Nutr. 22, 431–436 (1969).
Edwards, N.A., Hodgkinson, A.: Metabolic studies in patients with idopathic hypercalciuria. Clin. Sci. 29, 143–157 (1965).
Ekbom, K., Hed, R.: Calcium studies in partially gastrectomized patients with special reference to the oral calcium intake of calcium. Acta med. scand. 178, 193–201 (1965).
Evanson, J.M.: The response to infusion of parathyroid extract in hypocalcémie states. Clin. Sci. 31, 63–75 (1966).
Ewe, K.: Resorption und Sekretion von Calcium im menschlichen Jejunum. Klin. Wschr. 46, 661–666 (1968).
Ewe, K.: Intestinale Calcium-Resorption und ihre Störungen bei Osteoporose, M. Cushing und Hypoparathyreoidismus. Klinische und tierexperimentelle Untersuchungen. Habilitationsschrift, Mainz 1969.
Ewe, K.: Calcium transport in rat jejunum in vitro and in vivo. Naunyn-Schmiedebergs Arch. Pharmacol. (1972);
Ewe, K.: Naunyn-Schmiedeberg’s Arch. Pharmacol. 273, 352–365 (1972).
Fanconi, G., Girardet, P.: Familiärer persistierender Phosphatdiabetes mit Vitamin-D-resistenter Rachitis. Helv. paediat. Acta 7, 14–41 (1952).
Fanconi, G., Prader, A.: Die hereditäre Pseudomangelrachitis. Helv. paedit. Acta 24, 423–447 (1969).
Finkelstein, J.D., Schachter, D.: Active transport of calcium by intestine: effects of hypophysectomy and growth hormone. Amer. J. Physiol. 203, 873–880 (1962).
Fischermann, K., Mouridsen, H., Neesgaard, I., Worning, H., Zackao, A.: Gastric and pancreatic function and the absorption of iron, vitamin B12 and calcium after proximal gastric resection for cancer in the upper part of the stomach. Scand. J. Gastroent. 4, 697–703 (1969).
Fletcher, E. F., Jones, J.H., Morgan, D.B.: Bone disease in chronic renal failure. Quart. J. Med. 32, 321–339 (1963).
Flocks, R.H.: Calcium and phosphorus excretion in the urine of patients with renal or ureteral calculi. J. Amer. med. Ass. 113, 1466–1471 (1939).
Food and Nutrition Board: Recommended Dietary Allowances, 6th Ed. Washington: Nat. Acad. Sci. — Nat. Res. Council Publ. 1146. 1964.
Fraser, D., Koch, S.W., Scriver, C.R.: Hyperparathyroidism as the cause of hyperaminoaciduria and phosphaturia in human vitamin D deficiency. Pediat. Res. 1, 425–435 (1967).
Fraser, D., Salter, R.B.: The diagnosis and management of various types of rickets. Pediat. Clin. N. Amer. 417–441 (1958, May issue).
Fraser, D.R., Kodicek, E.: Unique biosynthesis by kidney of biologically active vitamin D metabolite. Nature (Lond.) 228, 764–766 (1970).
Frost, H.M.: Postmenopausal osteoporosis. A disturbance in oesteoclasia. J. Amer. Geriat. Soc. 9, 1078–1085 (1961).
Garner, A., Ball, J.: Quantitative observations on mineralized and unmineralized bone in chronic renal azotaemia and intestinal malabsorption syndrome. J. Path. Bact. 91, 545–561 (1966).
Gershon-Cohen, J., Jowsey, J.: The relationship of dietary calcium to osteoporosis. Metabolism 13, 221–226 (1964).
Gill, J.R., Bartter, F.C.: On the impairment of renal concentrating ability in prolonged hypercalciuria in man. J. clin. Invest. 40, 716–722 (1961).
Goldstein, R.A., Israel, H.L., Becker, K.L., Moore, C.F.: The infrequency of hypercalcemia in sarcoidosis. Amer. J. Med. 51, 21–30 (1971).
Gordan, G.S., Eisenberg, E.: The effect of oestrogens, androgens and corticosteroid on skeletal kinetics in man. Proc. roy. Soc. Med. 56, 1027–1030 (1963).
Gossman, H., Helms, H.: Knochenveränderungen bei intestinalen Resorptionsstörungen. Dtsch. med. Wschr. 93, 1219–1923 (1968).
Gruson, M., Cerland, M., Miravet, L., Paul, J., Hioco, D.: Action de la calcitonine de porc sur le transfert in vitro du calcium 45 au niveau du duodénum de rat normal et thyreoparathyreoidectomisé. CR. Acad. Sci. (Paris) 270, 1014–1017 (1970).
Halbritter, R.: Experimentelle Untersuchungen zur Lokalisation der enteralen Calcium-resorption. Z. ges. exp. Med. 154, 70–86 (1971).
Hamilton, R., Harrison, J., Fraser, D., Radde, I., Morecki, R., Paunier, L.: The small intestine in vitamin D dependent rickets. Pediatrics 45, 364–373 (1970).
Harmeyer, J., DeLuca, H.F.: Calcium-binding protein and calcium absorption after vitamin D administration. Arch. Biochem. 133, 247–254 (1969).
Harrell, G.T., Fisher, S.: Blood chemical changes in Boeck’s sarcoid, with particular reference to protein, calcium and phosphatase values. J. clin. Invest. 18, 687–693 (1939).
Harrison, A.R.: Some results of metabolic investigation in cases of renal stone. Brit. J. Urol. 31, 398–403 (1959).
Harrison, H.C., Harrison, H.E.: Dibutyryl cyclic AMP, vitamin D and intestinal permeability to calcium. Endocrinology 86, 756–760 (1970).
Harrison, H.E.: Vitamin D and calcium in phosphate transport. Pediatrics 28, 531–544 (1961).
Harrison, H.E.,Harrison, H.C.: Transfer of calcium 45 across intestinal wall in vitro in relation to action of vitamin D and Cortisol. Amer. J. Physiol. 199, 265–271 (1960).
Harrison, H.E., Harrison, H.C.: Theories of vitamin D action. In: Wasserman, R.H. (Ed.): The transfer of calcium and strontium across biological membranes, p. 229. New York-London: Academic Press 1963.
Harrison, M., Fraser, R.: Bone structure and metabolism in calcium-deficient rats. J. Endocr. 21, 197 (1960).
Harrison, H.E., Harrison, H.C., Mullan, B.: Calcium metabolism in osteoporosis. Acute and long-term responses to increased calcium intake. Lancet 1961I, 1015–1019.
Hass, G.M.: In: Bourne, G.H. (Ed.): The biochemistry and physiology of bone, p. 775. New York: Academic Press 1956.
Haussler, M.R., Norman, A.W.: The subcellular distribution of physiological doses of vitamin D3. Arch. Biochem. 118, 145–153 (1967).
Heaney, R.P.: Radiocalcium metabolism in human disuse osteoporosis. Amer. J. Med. 33, 188–200 (1962).
Heaney, R.P.: A unified concept of osteoporosis. Amer. J. Med. 39, 877–880 (1965).
Heaney, R.P., Skillman, T.G.: Secretion and excretion of calcium by the human gastro intestinal tract. J. Lab. clin. Med. 64, 29–41 (1964).
Heaney, R.P., Whedon, G.D.: Radiocalcium studies of bone formation rate in humanmetabolic bone disease. J. clin. Endocr. 18, 1246–1267 (1958).
Hegsted, D.M.: Symposium on human calcium requirements. J. Amer. med. Ass. 185, 588–593 (1963).
Henneman, P.H., Benedict, P.H., Forbes, A.P., Dudley, H.R.: Idiopathic hypercalciuria. New Engl. J. Med. 259, 802–807 (1958).
Henneman, P.H., Dempsey, E.F., Caroll, E.L., Albright, F.: The cause of hypercalciuria in sarcoidosis and its treatment with cortisone and sodium phytate. J. clin. Invest. 35, 1229–1242 (1956).
Herdman, R.C., Michael, A.F., Vernier, R.L., Kelly, W.D., Good, R.A.: Renal function and phosphorus excretion after human renal homotransplantation. Lancet 1966I, 121–124.
Herrath, D. v., Opitz, A., Koch, H.U., Knoop, H., Schäfer, K.: Effect of cortisone on vitamin D metabolism in rat plasma. Klin. Wschr. 49, 48–49 (1971).
Hesch, D.D., Henning, H.V., Gerlsch, W., Scheler, F.: Früherkennung von Störungen der intestinalen Calciumabsorption bei Niereninsuffizienz. Klin. Wschr. 49, 115–116 (1971).
Higgins, P.McR., Pridie, P.B.: Postgastrectomy osteomalacia: incidence after the no-loop and other types of gastrectomy. Brit. J. Surg. 53, 881–885 (1966).
Hill, L.F., van den Berg, C.J., Mawer, E.B.: Vitamin D metabolism in experimental uraemia: effects on intestinal transport 45Ca and on formation of 1,25-dihydroxycholecal-ciferol in the rat. Nature (Lond.) 232, 189–191 (1971).
Hillemand, P., Mialaret, J., Boutelier, D.: A propos d’une ostéomalacic après gastrectomie partielle avec anastomose gastro-jéjunale. Transformation par rétablissement du circuit duodenal. Arch. Mal. Appar. dig. 49, 489–500 (1960).
Hodgkinson, A.: Biochemical aspects of primary hyperparathyroidism: An analysis of 50 cases. Clin. Sci. 25, 231–242 (1963).
Hofmann, A.F.: Clinical implication of physiochemical studies on bile salts. Gastroenterology 48, 484–494 (1965).
Holdsworth, E.S.: Vitamin D and calcium absorption in the chick. Biochem. J. 96, 475–483 (1965).
Hurxthal, L.M., Vose, G.P.: The relationship of dietary calcium intake to radiographic bone density in normal and osteoporotic patients. Calc. Tiss. Res. 4, 245–256 (1969).
Ireland, A.W., Clubb, J.S., Neale, F.C., Posen, S., Reeve, T.S.: The calciferol requirements of patients with surgical hypoparathyroidism. Ann. intern. Med. 69, 81–90 (1968).
Jackson, W.P.U., Dancaster, C.: A consideration of the hypercalciuria in sarcoidosis, idiopathic hypercalciuria and that produced by vitamin D. A new suggestion regarding calcium metabolism. J. clin. Endocr. 19, 658–680 (1959).
Jaworski, Z.F., Brown, E.M., Fedoruk, S., Seitz, H.: A method for the study of calcium absorption by the human gut using a standard dose of calcium labeled with Ca 47. New Engl. J. Med. 269, 1103–1111 (1963).
Joplin, G.F., Melvin, K.E.W., Hepner, G.W., Neale, G., Bordier, P.: Calcium metabolism and bone histology in adult celiac disease. Calc. Tiss. Res. Z. Suppl., 62 (1968).
Jowsey, J.: Age changes in human bone. Clin. Orthop. 17, 210–212 (1960).
Jowsey, J.: Effect of long-term administration of porcine calcitonin in the development of dietary osteoporosis in cats. Endocrinology 85, 1196–1201 (1969).
Jowsey, J., Kelly, P.J., Riggs, B.L., Bianco, A.J., Scholz, D.A., Gershon-Cohen, J.: Quantitative microradiographic studies of normal and osteoporotic bone. J. Bone Jt Surg. 47-A, 785 (1965).
Juergens, J.S., Scholz, D.A., Wollaeger, E.E.: Severe osteomalacia associated with occult steatorrhea to nontropical sprue: report of 5 cases. Arch. intern. Med. 98, 774–782 (1956).
Kahn, A., Snapper, I., Drucker, A.: Corticosteroid-induced tetany in latent hypoparathyroidism. Arch. intern. Med. 114, 434–438 (1964).
Kallfelz, F.A., Taylor, A.N., Wasserman, R.N.: Calcium binding factor in rat intestinal mucosa. Proc. Soc. exp. Biol. 125, 54–58 (1967).
Kaye, M., Silverman, M.: Calcium metabolism in nephritis. J. Lab. clin. Med. 66, 535–548 (1965).
Kehayoglu, A.K., Agnew, J.E., Turnberg, L.A., Sherlock, S.: 47Calcium absorption in parenchymatous and biliary liver disease. Gut 12, 978–983 (1971).
Kehayoglu, A.K., Holdsworth, C.D., Agnew, J.E., Whelton, M.J., Sherlock, S.: Bone disease and calcium absorption in primary biliary cirrhosis with special reference to vitamin D therapy. Lancet 1968aI, 715–719.
Kehayoglu, A.K., Williams, H.S., Whimster, W.F., Holdsworth, C.D.: Calcium absorption in the normal, bile-duct ligated, and cirrhotic rat, with observations on the effect of long- and medium-chain triglycerides. Gut 9, 597–603 (1968b).
Kessner, D.M., Epstein, F.H.: Effect of renal insufficiency on gastrointestinal transport of calcium. Amer. J. Physiol. 209, 141–145 (1965).
Kierkens, R., Lundh, G.: Intestinal digestion and absorption after Billroth II gastrectomy. Acta chir. scand. 113, 349–356 (1957).
Kimberg, D.V.: Effects of vitamin D and steroid hormones on the active transport of calcium by the intestine. New Engl. J. Med. 280, 1396–1405 (1969).
Kimberg, D.V., Baerg, R.D., Gershon, E., Grandusius, R.T.: Effect of cortisone treatment on the active transport of calcium by the small intestine. J. clin. Invest. 50, 1309–1321 (1971).
Kimberg, D.V., Schachter, D., Schenker, H.: Active transport of calcium by intestine: effects of dietary calcium. Amer. J. Physiol. 200, 1256–1262 (1961).
Kinney, U.R., Tauxe, W.N., Dearing, W.H.: Isotopic tracer studies of intestinal calcium absorption. J. Lab. clin. Med. 66, 187–203 (1965).
Kinsella, V.J., Hennessy, W.B., George, E.P.: A study on postgastrectomy malabsorption (abstr.) Gut 1, 372–373 (1960).
Kleeman, C.R. (Ed.): Divalent ion metabolism and osteodystrophy in chronic renal failure. Arch. int. Med. Symp. 3, 124, 670–682 (1969).
Ko, K.W., Fellers, F.X.: On the mechanisms of simple familial hypophosphatemic rickets. Amer. J. Dis. Childr. 102, 437–439 (1961).
Kocian, J.: Kalziumresorption bei Dünndarmerkrankungen. Z. Gastroenterologie 8, 480–488 (1970).
Kodicek, E.: The biosynthesis of 14C-labeled ergocalciferol. Biochem. 60, 25 (1955).
Kodicek, E., Cruickshank, E.M., DeLuca, H.F., Raisz, L.G.: Effects of vitamin D and parathyroidectomy on the absorption of calcium-45 from in vivo loops of small intestine. In: Blackwood, H.J.J. (Ed.): Bone and Tooth Symposion, Oxford 1963, p. 363. New York: MacMillan Comp. 1964.
Kraintz, L., Cramer, C.F.: Lack of effect of thyrocalcitonin from gut loops in the dog. Proc. Endocr. Soc. 48, 70 (1966) Abstr.
Krawitt, E.L., Schedl, H.P.: In vivo calcium transport by rat small intestine. Amer. J. Physiol. 214, 232–236 (1968).
Lafferty, F.W., Pearson, O.H.: Skeletal, intestinal and renal calcium dynamics in hyperparathyroidism. J. clin. Endocr. 23, 891–902 (1963).
Larsson, S.E.: On the development of osteoporosis. Acta orthopaed. scand. 1969, Suppl. 120.
Lau, Sh., Goldman, A.G., Grossmann, J.: Metabolic studies on aluminum gel phosphorus depletion. Fed. Proc. 19, 251–255 (1960).
Lawson, D.E.M.: Vitamin D: New findings on its metabolism and its role in calcium nutrition. Proc. Nutr. Soc. 30, 47–58 (1971).
Lawson, D.E.M., Fraser, D.R., Kodicek, E., Morris, H.R., Williams, D.H.: Identification of 1,25 dihydrocholecalciferol, a new kidney hormone controlling calcium metabolism. Nature (Lond.) 230, 228–230 (1971).
Lichtwitz, A., deSèze, S., Cachin, M., Guillaumat, M., Hioco, D., Pergola, F.: Les troubles du métabolisme phosphocalcique chez les gastrectomisés. Sem. Hôp. Paris 37, 3391–3400 (1961a).
Lichtwitz, A., deSéze, S., Cachin, M., Guillaumat, M., Hioco, D., Pergola, F.: Physiopathologie des modifications du métabolism phosphocalcique chez les gastrectomisés avec exclusion du duodénum. Sem. Hôp. Pads 37, 3401–3411 (1961b).
Lichtwitz, A., Parlier, R.: Les parathyroides et le metabolisme phosphocalcique. II. Rôle du rein et de l’intestin. Présse méd. 67, 134–137 (1959).
Lifshitz, F., Harrison, H.C., Harrison, H.E.: Influence of parathyroid function upon the in vitro transport of calcium and phosphate by the rat intestine. Endocrinology 84, 912–917 (1969).
Liu, S.H., Chu, H.I.: Studies of calcium and phosphorus metabolism with special reference to pathogenesis and effects of dihydrotachysterol (A.T. 10) and iron. Medicine (Bait.) 22, 103–1061 (1943).
Lumb, G.A., Mawer, E.B., Stanbury, S.W.: The apparent vitamin D resistance of chronic renal failure. Amer. J. Med. 50, 421–441 (1971).
Lundh, J., DeLuca, H.F.: Biologically active metabolite of vitamin D3 from bone, liver and blood serum. J. Lipid Res. 7, 739–744 (1966).
Lutwak, L., Sharpiro, J.R.: Calcium absorption in man based on large liquid scintillation counter studies. Science 144, 1155–1157 (1964).
Maher, J.F., Freeman, R.B., Schreiner, G.E.: Hemodialysis for chronic renal failure. II. Biochemical and clinical aspects. Ann. intern. Med. 62, 535–550 (1965).
Malm. O.J.: Calcium requirements and adaptation in adult men. Scand. J. clin. Lab. Invest. 10, Suppl. 36 (1958).
Markus, C.S., Lengemann, F.W.: Absorption of Ca4t and Srtt from solid and liquid food at various levels of the alimentary tract of the rat. J. Nutr. 77, 155–160 (1962).
Martin, D.L., DeLuca, H.F.: Calcium transport and the role of vitamin D. Arch. biochim. Biophys. (Amst.) 134, 139–148 (1969a).
Martin, D.L., DeLuca, H.F.: Influence of sodium on calcium transport by the rat small intestine. Amer. J. Physiol. 216, 1351–1359 (1969b).
Mawer, E.B., Lumb, G.A., Schäfer, K., Stanbury, S.W.: The metabolism of isotopically labelled vitamin D3 in man: the influence of the state of vitamin D nutrition. Clin. Sci. 40, 39–53 (1971).
Mazzuoli, G.F., Terrenato, L.: Intestinal absorption and skeletal dynamics of calcium in acromegaly. Calc. Tiss. Proc. 3rd Europ. Symposion Davos 1965. p. 254–258. Berlin-Heidelberg-New York: Springer 1966.
McCollum, E.V., Simmonds, N., Becker, J.E. et al.: Studies on experimental rickets. Bull. Johns Hopkins Hosp. 33, 229 (1922).
McMillan, D.E., Freeman, R.B.: The milk alkali syndrome: a study of the acute disorder with comments on the development of the chronic condition. Medicine (Bait.) 44, 485–501 (1965).
Melancon, M.J., DeLuca, H.F.: Vitamin D stimulation of calcium-dependant adenosine triphosphate in chick intestinal brush borders. Biochemistry 9, 1658–1664 (1970).
Meulengracht, E., Meyer, A.R.: Osteomalacia of the spinal column. Acta med. scand. 92, 584–602 (1937).
Milhaud, G., Vesin, P.: Hypocalciuria and calcium absorption (Letter to the editor). Lancet 1963II, 40
Miller, G.G.: The treatment of osteoporosis. A report of a double blind clinical therapeutical trial. Geront. Clin. 1962, 244–252.
Morgan, D.B., Paterson, C.R., Woods, C.G., Pulvertaft, C.N., Fourman, P.: Search for osteomalacia in 1228 patients after gastrectomy and other operations on the stomach. Lancet 1965II, 1085–1088.
Morgan, D.B., Pulvertaft, C.N., Fourman, P.: Effect of age on the loss of bone after gastric surgery. Lancet 1966II, 772–773.
Moss, A.J., Waterhouse, Terry, R.: Gluten-sensitive enteropathy with osteomalacia but without steatorrhea. New Engl. J. Med. 272, 825–830 (1965).
Mueller, K.H., Soergel, K.H.: Pathophysiologische Veränderungen bei der Vitamin D resistenten Rachitis. Z. Orthop. Grenzgeb. 105, 74–83 (1968).
Muldowney, F.P.: Metabolie bone disease secondary to renal and intestinal disorders. Calif. Med. 110, 397–409 (1969).
Munck, O.: Osteoporosis due to malabsorption of calcium responding favourably to large doses of vitamin D. Quart. J. Med. 33, 209–221 (1964).
Myrtle, J.F., Haussler, M.R., Norman, A.W.: Evidence for the biologically active form of cholecalciferol in the intestine. J. biol. Chem. 245, 1190–1196 (1970).
Myrtle, J.F., Norman, A.W.: Vitamin D: a cholecalciferol metabolite highly active in promoting intestinal calcium transport. Science 171, 79–82 (1971).
Nassim, J.R., Saville, P.D., Cook, P.B., Mulligan, L.: The effect of vitamin D and gluten-free diet in idiopathic steatorrhea. Quart. J. Med. 28, 141–162 (1959).
Neville, P.F., DeLuca, H.F.: The synthesis of (1, 2-3H) vitamin D3 and the tissue localisation of a 0.25 microgram (10 I.U.) dose per rat. Biochemistry 5, 2201–2207 (1966).
Nicolaysen, R., Eeg-Larsen, N., Malm, O.J.: Physiology of calcium metabolism. Physiol. Rev. 33, 424–444 (1953).
Niepmann, W.: Experimentelle Untersuchungen zur intestinalen Calciumresorption in Abhängigkeit von der Magenazidität beim Menschen. Klin. Wschr. 39, 1064–1070 (1961).
Nordin, B.E.C.: Osteomalacia, osteoporosis and calcium deficiency. Clin. Orthop. 17, 235–237 (1960).
Nordin, B.E.C.: The pathogenesis of osteoporosis. Lancet 1961aI, 1011–1014.
Nordin, B.E.C.: Effect of malabsorption syndrome on calcium metabolism. Proc. roy. Soc. Med. 54, 497–500 (1961b).
Nordin, B.E.C.: Calcium balance and calcium requirement in spinal osteoporosis. Amer. J. clin. Nutr. 10, 348–390 (1962).
Nordin, B.E.C.: Hormones and calcium metabolism. Calc. Tiss. Proc. 3rd Europ. Symposion Davos 1965, p. 226–241. Berlin-Heidelberg-New York: Springer 1966.
Nordin, B.E.C., Smith, D.A.: Diagnostic procedures in disorders of calcium metabolism. London: J. A. Churchill Ltd. 1965.
Nordin, B.E.C., Smith, D.A., Nisbet, J.: Bone mineralization and destruction rates determined by continuous feeding of radiocalcium. Clin. Sci. 27, 111–119 (1964).
Young, M.M., Oxby, C., Bulusu, L.: Calculation of calcium absorption rate from plasma radioactivity. Clin. Sci. 35, 177–182 (1968).
Norman, A.W.: Actinomycin D and the response to vitamin D. Science 149, 184–186 (1965).
Young, M.M., Evidence for a new kidney-produced hormone, 1,25-dihydroxycholecalciferol, the proposed biologically active form of vitamin D. Amer. J. Clin. Nutr. 24, 1346–1351 (1971).
Young, M.M., Lund, J., DeLuca, H.F.: Biologically active forms of vitamin D3 in kidney and intestine. Arch. biochim. Biophys. (Amst.) 108, 12–21 (1964).
Ogg, C.S.: The intestinal absorption of 47 calcium by patients in chronic renal failure. Clin. Sci. 34, 467–471 (1968).
Olson, E.B., DeLuca, H.F.: 25-hydroxycholecalciferol: direct effect on calcium transport: Science 165, 405–407 (1969).
Owen, E.C., Irving, J.T., Lyall, A.: The calcium requirement of older male subjects with special reference to the genesis of senile osteoporosis. Acta med. scand. 103, 235–250 (1940).
Pak, C.Y.C., DeLuca, H.F., Chaves de los Rios, J.M., Suda, T., Ruskin, B., Delea, C.S.: Treatmemt of vitamin D-resistant hypoparathyroidism with 25-hydroxycholecalciferol. Arch. intern. Med. 126, 239–247 (1970).
Pak, C.Y.C., Zisman, E., Evens, R., Jowsey, J., Delea, C.S., Bartter, F.C.: The treatment of osteoporosis with calcium infusions. Amer. J. Med. 47, 7–16 (1969).
Parfitt, A.M., Higgins, B.A., Nassim, J. R., Coolins, J.A., Hilb, A.: Metabolic studies in patients with hypercalciuria. Clin. Sci. 27, 463–482 (1964).
Paterson, C.R., Woods, C.G., Pulvertaft, C.N., Fourman, P.: Osteomalacia after gastrectomy. A response to very small doses of vitamin D. Lancet 1965II, 1089–1091.
Peacock, M., Hodgkinson, Nordin, B.E.C.: Importance of dietary calcium in the definition of hypercalciuria. Brit. med. J. 1967III, 469–471.
Peacock, M., Nordin, B.E.C.: Tubular reabsorption of calcium in normal and hypercalciuric subjects. J. clin. Path. 21, 353–358 (1968).
Pendras, J.P., Erickson, R.V.: Hemodialysis: a successful therapy for chronic uremia. Ann. intern. Med. 64, 292–311 (1966).
Phillips, M.J., Cooke, J.N.C.: Relation between urinary calcium and sodium in patients with idiopathic hypercalciuria. Lancet 1967I, 1354–1357.
Ponchon, G., Kennan, A.L., DeLuca, H.F.: Activation of vitamin D by the liver. J. clin. Invest. 48, 2032–2037 (1969).
Powell, R.C., Deiss, W.P.: Symptomatic osteomalacia secondary to clinically occult causes. Ann. intern. Med. 54, 1280–1289 (1961).
Prader, A., Illig, R., Heierli, E.: Eine besondere Form der primären Vitamin D-resistenten Rachitis mit Hypocalciämie und autosomal-dominantem Erbgang: die hereditäre Pseudomangelrachitis. Helv. paediat. Acta 16, 452–468 (1961).
Pulvertaft, C.N., Juffman, J.E., Rolson, E.B., Harris, H., Langman, M.S.J.: Isoenzymes of alkaline phosphatase in patients operated upon for peptic ulcer. Lancet 1967I, 237–239.
Rasmussen, H., DeLuca, H.F., Arnaud, C., Hawker, C., Stedingk, M.v.: The relationship between vitamin D and parathyroid hormone. J. clin. Invest. 42, 1940–1946 (1963).
Reifenstein, E.C.: The relationship of steroid hormones to the development and the management of osteoporosis in aging people. Clin. Orthop. 10, 206–253 (1957).
Riggs, B.L., Kelly, P. J., Kinney, V.R., Scholz, D.A., Bianco, A.J.: Calcium deficiency and osteoporosis. Observations in one hundred and sixty-six patients and critical review of the literature. J. Bone Jt Surg. A 49, 915–924 (1967).
Rikkers, H., DeLuca, H. F.: An in vivo study of the carrier proteins of 3H-vitamin D3 and D4 in rat serum. Amer. J. Physiol. 213, 380–386 (1967).
Ritz, E.: Intestinaler Calcium-Transport bei Urämie. Verh. dtsch. Ges. inn. Med. 75, 137–140 (1969).
Sack, H.: Die Calciumresorption. Untersuchungen zur oralen Calciumtherapie. Dtsch. med. Wschr. 95, 398–401 (1970).
Sadowski, P., Klaus, D.: Die enterale Calcium-Resorption bei Störungen des Calcium-Stoffwechsels. Med. Welt 19, NF 2284–2250 (1968).
Sallis, J.D., Holdsworth, E.S.: Calcium metabolism in relation to vitamin D and adrenal function in the chick. Amer. J. Physiol. 203, 506–512 (1962).
Sampson, H.W., Matthews, J.C., Martin, J.H., Kunin, A.S.: An electron microscopic localization of calcium in the small intestine of normal, rachitic and vitamin D-treated rats. Calc. Tiss. Res. 5, 305–316 (1970).
Sataline, L.R., Buch, P., Foxman, D.: Osteomalacia following partial gastrectomy: Pathophysiologic and therapeutic considerations. Amer. J. Dig. Dis. 12, 1160–1168 (1967).
Saville, P.D.: Symptomatic osteoporosis and the menopause. Clin. Orthop. 55, 43–49 (1967).
Schachter, D.: Vitamin D and the active transport of calcium by the small intestine. In: Wasserman, R.H. (Ed.): The transfer of calcium and strontium across biological membranes, p. 197. New York-London: Academic Press 1963.
Schachter, D., Dowdle, E.B., Schenker, H.: Active transport of calcium by the small intestine of the rat. Amer. J. Physiol. 198, 263–268 (1960a).
Schachter, D., Dowdle, E.B., Schenker, H.: Accumulation of Ca45 by slices of the small intestine. Amer. J. Physiol. 198, 275–279 (1960b).
Schachter, D., Finkelstein, J.D., Kowarski, S.: Metabolism of vitamin D. I. Preparation of radioactive vitamin D and its intestinal absorption in the rat. J. clin. Invest. 43, 787–796 (1964).
Kowarski, S.: Radioactive vitamin D: preparation, metabolism and mechanism of action. Bull. N. Y. Acad. Med. 41, 241 (1965).
Kowarski, S., Rosen, S.M.: Active transport of Ca45 by the small intestine and its dependence on vitamin D. Amer. J. Physiol. 196, 357–362 (1959).
Schäfer, K., Opitz, A.: Aktuelle Probleme azotämischer Knochenerkrankungen. Dtsch. med. Wschr. 95, 84–88 (1970).
Schäfer, K., Schäfer, P., Koeppe, P., Opitz, A., Höffler, D.: Untersuchungen zur Frage der urämischen Osteopathie: Störungen der intestinalen Calcium-Resorption in Abhängigkeit von der Nierenfunktion. Dtsch. med. Wschr. 93, 1018–1022 (1968).
Schäfer, K., Schäfer, P., Koeppe, P., Opitz,A., Höffler, D.: Untersuchungen zur Therapie der urämischen Osteopathie. Dtsch. med. Wschr. 94, 70–12 (1969).
Schwartz, E., Chokas, W.B., Panariello, V.A.: Metabolie balance studies of high calcium intake in osteoporosis. Amer. J. Med. 36, 233–249 (1964).
Schwarz, G.: Grundlagen der alimentären Kalziummangel-Therapie und der oralen Kalzium-Therapie der Osteoporose. Fortschr. Med. 1964, 853–856.
Scott, G.B., Williams, M.J., Clark, D.G.: Comparison of jejunal mucosa in postgastrectomy states, idiopathic steatorrhea and controls using the dissecting microscope and conventional histological methods. Gut 5, 553–562 (1964).
Scriver, C.R.: Vitamin D dependency. Pediatrics 45, 361–363 (1970).
Scudamore, H.N., Green, P. A., Hoffman, H.N., Rosevear, J.W., Tauxe, W.N.: Scleroderma (progressive systemic sclerosis) of the small intestine with malabsorption. Amer. J. Gastroent. 49, 193–208 (1968).
Seruka, T. J., Borle, A.B.: Calcium in the intestinal contents of rats on different calcium diets. Proc. Soc. exp. Biol. 131, 1420–1423 (1969).
Shah, B.G., Draper, H.H.: Depression of calcium absorption in parathyreoidectomized rats. Amer. J. Physiol. 211, 963–966 (1966).
Sharma, O., Trowell, J., Cohen, N., Bird, R., James, D.G.: Abnormal calcium metabolism in sarcoidosis. La Sarcoidose. IVe Conférence internationale p. 627–632, Paris 1966.
Sherman, H.D.: Calcium and phosphorus in foods and nutrition. New York: Columbia Univ. Press 1947.
Sjöberg, H.E., Nilson, L.H.: Retention of oral 47Ca in patients with intestinal malabsorption: regional enteritis and pancreatic insufficiency. Scand. J. Gastroent. 5, 265–272 (1970).
Sjöberg, H.E., Reizenstein, P.: Nutritional studies in the dumping syndrome. III. Retention of orally administered 47Ca in patients with gastrectomy. Amer. dig. Dis. 12, 1156–1159 (1967).
Smith, R.W., Frame, B.: Concurrent axial and appendicular osteoporosis: its relation to calcium consumption. New Engl. J. Med. 273, 73–78 (1965).
Spencer, H., Lewin, I., Somachson, J.: Influence of dietary and hormonal factors in radium-strontium metabolism in man. In: Lenihan, J.M.A., Loutit, J.F., Martin, J.H. (Eds.): Strontium metabolism. Academic Press 1967.
Spencer, H., Menczel, J., Lewin, I., Somachson, J.: Absorption of calcium in osteoporosis. Amer. J. Med. 37, 223–234 (1964).
Stanbury, S.W.: The treatment of renal osteodystrophy. Ann. intern. Med. 65, 1133–1138 (1966).
Spencer, H.: Bone disease in uremia. Amer. J. Med. 44, 714–724 (1968).
Stauffer, M., Rich, C.: Direct action of vitamin and lactose on bone in osteomalacia. J. clin. Invest. 46, 1119 (1967).
Stickler, G.B.: External calcium and phosphorus balances in vitamin resistant rickets: comparative view. J. Pediat. 63, 942–948 (1963).
Spencer, H.: Personal communication 1971.
Spencer, H., Beabont, J.W., Riggs, B.L.: Vitamin D-resistant rickets: clinical experiences with 41 typical familial hypophosphatemic patients and 2 atypical nonfamilial cases. Mayo Clin. Proc. 45, 197–218 (1970).
Stohs, S.J., DeLuca, H.F.: Subcellular location of vitamin D and its metabolites in intestinal mucosa after 10 IU dose. Biochemistry 6, 3338–3349 (1967).
Tanaka, Y., DeLuca, H.F., Omdahl, J., Holick, F.: Mechanism of action of 1, 25-dihy-droxycholecalciferol on intestinal calcium transport. Proc. nat. Acad. Sci. (Wash.) 68, 1286–1288 (1971).
Taylor, A.N., Wasserman, R.H.: Vitamin D3-dependent factor influencing calcium binding by homogenates of chick intestinal mucosa. Nature (Lond.) 205, 248–251 (1965).
Taylor, A.N., Wasserman, R.H.: Vitamin D-induced calcium binding protein: partial purification, electrophoretic visualization and its tissue distribution. Arch. Biochem. 119, 536–540 (1967).
Taylor, A.N., Wasserman, R.H., Jowsey, J.: A vitamin D-dependent calcium binding protein in canine intestinal mucosa. Fed. Proc. 27, 675–678 (1968).
Taylor, A.N., Wasserman, R.H.: Immunfluorescent localization of vitamin D-dependent calcium binding protein. J. Histochem. Cytochem. 18, 107–115 (1969).
Taylor, R.L., Lynch, H.J., Wysor, W.G.: Seasonal influence of sunlight on the hypercalcemia of sarcoidosis. Amer. J. Med. 34, 221–227 (1963).
Telfer, S.V.: Studies in calcium and phosphorus metabolism. Part 3: The absorption of calcium and phosphorus and their fixation in the skeleton. Quart. J. Med. 17, 245 (1923/24).
Thompson, G.R., Lewis, B., Booth, C.C.: Vitamin D absorption after partial gastrectomy. Lancet 1966a I, 457–458.
Thompson, G.R., Lewis, B., Booth, C.C.: Absorption of vitamin-D3 -3H in control subjects and patients with intestinal malabsorption. J. clin. Invest. 45, 94–102 (1966c).
Thompson, G.R., Neale, G., Watts, J. M., Booth, C.C.: Detection of vitamin D deficiency after gastrectomy: a response to very small doses of vitamin D. Lancet 1965 II, 1089–1091.
Thompson, G.R., Neale, G., Watts, J. M., Booth, C.C.: Detection of vitamin-D deficiency after partial gastrectomy. Lancet 1966b I, 623–626.
Uehlinger, E.: Der Knochen bei gastrointestinalen Erkrankungen. In: Aktuelle Gastroenterologie, S. 149. Stuttgart: Thieme 1968.
Verner, J.V., Engel, F.L., McPherson, H.T.: Vitamin D intoxication: report of two cases treated with cortisone. Ann. intern. Med. 48, 765–773 (1938).
Vinther-Paulsen, N.: Calcium and phosphate intake in senile osteoporosis. Geriatrics 8, 76–79 (1953).
Wangel, A.G., Deller, D.J.: Intestinal motility in man. II. The behaviour of the small intestine following partial gastrectomy with particular reference to the dumping syndrome. Gastroenterology 48, 45–57 (1965).
Wasserman, R.H.: Vitamin D and the absorption of calcium and strontium in vivo. In: Wasserman, R.H. (Ed.): The transfer of calcium and strontium across biological membranes, p. 211. New York-London: Academic Press 1963.
Wasserman, R.H., Comar, C.L.: The parathyroid and the intestinal absorption of calcium, strontium and phosphate ions in the rat. Endocrinology 69, 1074–1080 (1961).
Wasserman, R.H., Corradino, R.A., Taylor, A.N.: Vitamin D-dependent calcium binding protein: purification and some properties. J. biol. Chem. 243, 3978–3986 (1968).
Wasserman, R.H., Taylor, A.N.: Vitamin D3-induced calcium-binding protein in chick intestinal mucosa. Science 152, 791–793 (1966).
Wasserman, R.H.: Vitamin D-dependent calcium binding protein: response to some physiological and nutritional variables. J. biol. Chem. 243, 3987–3993 (1968).
Wasserman, R.H., Taylor, A.N.: Some aspects of the intestinal absorption of calcium with special reference to vitamin D. In: Comar, C.L., Bronner, F. (Eds.): Mineral metabolism, Vol. III. Calcium physiology, p. 321–403. New York-London: Academic Press 1969.
Wasserman, R.H., Taylor, A.N.: Evidence for a vitamin D3-induced calcium binding protein in new-world primates. Proc. Soc. exp. Biol. 136, 25–28 (1971).
Webling, D.D.A., Holdsworth, E.S.: The effect of bile, bile acids and detergents on calcium absorption in the chick. Biochem. J. 97, 408–421 (1965).
Wasserman, R.H., Taylor, A.N.: Bile salts and calcium absorption. Biochem. J. 100, 652–660 (1966).
Wensel, R.H., Rich, C., Brown, A.C., Volwiler, W.: Absorption of calcium measured by intubation and perfusion of the intact human small intestine. J. clin. Invest. 48, 1768 to 1775 (1969).
Whedon, G.D.: Effects of high calcium intakes on bones, blood and soft tissues; relationship of calcium intakes to balances in osteoporosis. Fed. Proc. 18, 1112–1118 (1959).
Williams, G.A., Bowser, E.N., Henderson, W.J., Uzgiries, V.: Effects of vitamin D and cortisone on intestinal absorption of calcium in rat. Proc. Soc. exp. Biol. 106, 664–666 (1961).
Williams, T.F., Winter, R.W., Burnett, C.H.: Familial (hereditary) vitamin D-resistant rickets with hypophosphatemia. In: Stanburg, J.B., Wyngaarden, J.B., Fredrichson, D.S. (Eds.): The metabolic basis of inherited disease, 2nd Ed., p. 1179–1204. New York: McGraw-Hill Book Comp. 1966.
Wills, M.R., Wortman, J., Pak, C.Y.C., Bartter, F.C.: The role of parathormone in the gastro-intestinal absorption of calcium. Clin. Sci. 39, 89–94 (1970a).
Wills, M.R., Zisman, E., Wortman, J., Evens, R.G., Pak, C.Y. C., Bartter, F.C.: The measurement of intestinal calcium absorption by external radioisotope counting: application to study of nephrolithiasis. Clin. Sci. 39, 95–106 (1970b).
Wilson, R.E., Bernstein, D.S., Murray, J.E., Moore, F.D.: Effects of parathyreoidectomy and kidney transplantation on renal osteodys trophys. Amer. J. Surg. 110, 384–393 (1965).
Wilson, T.H.: Intestinal absorption, p. 148. Philadelphia-London: W.B. Saunders 1962.
Windaus, A.: Beobachtungen über das antirachitische Vitamin. Klin. Wschr. 6, 666–667 (1927).
Wiseman, G.: Absorption from the intestine, p. 208ff. New York-London: Academic Press 1964.
Young, J.M.: Cause of raised serum-alkaline-phosphatase after partial gastrectomy and other malabsorption states. Lancet 1966 I, 1132–1134.
Zull, J.E., Czernowska-Misztal, DeLuca, H.F.: Actinomycin D inhibition of vitamin D action. Science 149, 182–183 (1965).
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Ewe, K. (1972). Calcium Absorption in Health and Disease. In: Frick, P., von Harnack, GA., Muller, AF., Prader, A., Schoen, R., Wolff, H.P. (eds) Ergebnisse der Inneren Medizin und Kinderheilkunde. Ergebnisse der Inneren Medizin und Kinderheilkunde, vol 33. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65420-6_6
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