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Wirkung hoher Sauerstoffdrucke auf das Zentralnervensystem

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Book cover Sauerstoffüberdruckbehandlung

Zusammenfassung

Es ist seit langem bekannt, daß Sauerstoff ein Gift darstellt, das bei längerer Applikation in hohen Konzentrationen tödlich wirkt. Klinische und experimentelle Befunde legen die Annahme nahe, daß das Gehirn zu den Organen gehört, die auf hohe Sauerstoffdrucke besonders empfindlich reagieren.

Mit Unterstützung der Landesamtes für Forschung beim Ministerpräsidenten des Landes Nordrhein-Westfalen

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References

  1. Anderson, B., Saltzman, H. A.: Hyperbaria, Hybaroxia, and the Retinal and Cerebral Vessels. Headache 5, 73 (1965).

    Article  PubMed  Google Scholar 

  2. Anderson, B., McIntosh, H. D.: Retinal Circulation. Ann. Rev. Med. 18, 15 (1967).

    Article  PubMed  Google Scholar 

  3. Balentine, J. D.: Pathologic Effects of Exposure to High Oxygen Tensions. New Engl. J. Med. 275, 1038 (1966).

    Article  PubMed  CAS  Google Scholar 

  4. Balentine, J. D., Gutsche, B. B.: Central Nervous System Lesions In Rats Exposed To Oxygen At High Pressure. Amer. J. Pathol. 48, 107 (1966).

    CAS  Google Scholar 

  5. Balentine, J. D., Gutsche, B. B.: Pathogenesis of Central Nervous System Lesions Induced by Exposure to Hyperbaric Oxygen. Amer. J. Path. 53, 1097 (1968).

    PubMed  CAS  Google Scholar 

  6. Bean, J. W.: Factors Influencing Clinical Oxygen Toxicity. Ann. N. Y. Acad. Sci. 117, 745 (1965).

    PubMed  CAS  Google Scholar 

  7. Bert, P.: La Pression Barometrique. Paris, France 1878 (zit. n. Zirkle et al. [32]).

    Google Scholar 

  8. Desai, I. D., Tappel, A. L.: Damage to proteins by peroxidized lipids. J. Lipid Res. 4, 204 (1963).

    PubMed  CAS  Google Scholar 

  9. Gillen, H. W.: Oxygen Convulsions in Man. Proc. III. Int. Conf. Hyberbaric Medicine 1, 217 (1966).

    Google Scholar 

  10. Gottlieb, S. F., Jagodzinski, R. V.: Role of THAM in protecting mice agains convulsive episodes caused by exposure to oxygen under high pressure. Proc. Soc. exp. Biol. 112, 427 (1963).

    PubMed  CAS  Google Scholar 

  11. Goulon, M., Levy-Alcover, M. A., Nouailhat, F., Dordain, G.: The EEG in hyperbaric oxygen therapy. Electroenceph. clin. Neurophysiol. 25, 90 (1968).

    PubMed  CAS  Google Scholar 

  12. Gutsche, B. B., Harp, J. R., Stephen, C. R.: Physiologic Responses of the Anesthetized Dog to Oxygen at Five Atmospheres Absolute. Anesthesiology 27, 615 (1966).

    Article  PubMed  CAS  Google Scholar 

  13. Harel, D., Kerem, D., Lavy, S.: The Influence of high Oxygen Pressure on the Electrical Activity of the Brain. Electroenceph. clin. Neurophysiol. 26, 310 (1969).

    Article  PubMed  CAS  Google Scholar 

  14. Harp, J. R., Gutsche, B. B., Stephen, C. R.: Effect of Anesthetics on Central Nervous System Toxicity of Hyperbaric Oxygen. Anesthesiology 27, 608 (1966).

    Article  PubMed  CAS  Google Scholar 

  15. Haugaard, N.: Poisoning of Cellular Reactions by Oxygen. Ann. N. Y. Acad. Sci. 117, 736 (1965).

    PubMed  CAS  Google Scholar 

  16. Haugaard, N.: Cellular Mechanism of Oxygen Toxicity. Physiol. Rev. 48, 311 (1968).

    PubMed  CAS  Google Scholar 

  17. Hollin, J. S. A., Espinosa, O. E., Sukoff, M. H., Jacobson, J. W.: The Effect of Hyperbaric Oxygenation on Cerebrospinal Fluid Oxygen. J. Neurosurg. 29, 229 (1968).

    Article  PubMed  CAS  Google Scholar 

  18. Jamieson, D., Van den Brenk, H. A. S.: The Effects of Antioxidants on High Pressure Oxygen Toxicity. Biochem. Pharmacol. 13, 159 (1964).

    Article  PubMed  CAS  Google Scholar 

  19. Joanny, P., Corriol, J., Brue, F.: Hyperbaric Oxygen: Effects on Metabolism and Ionic Movement in Cerebral Cortex Slices. Science 167, 1510 (1970).

    Article  Google Scholar 

  20. Kann, H. E., Mengel, C. E., Smith, W., Horton, B.: Oxygen toxicity and vitamin E. Aerospace Med. 35, 840 (1964).

    PubMed  CAS  Google Scholar 

  21. Kaplan, S. A., Stein, S. N.: Effects of Oxygen at high Pressure on the Transport of Potassium, Sodium and Glutamate in Guinea Pig Brain Cortex. Amer. J. physiol. 190, 157 (1957).

    PubMed  CAS  Google Scholar 

  22. Kety, S. S., Schmidt, C. F.: The Effects of altered arterial Tensions of Carbon Dioxide and Oxygen on Cerebral Blood Flow and cerebral Oxygen Consumption of normal young men. J. clin. Invest. 27, 484 (1948).

    Article  CAS  Google Scholar 

  23. Lambertsen, C. J., Kough, R. H., Cooper, D. Y., Emmel, G. L., Loeschcke, H. H., Schmidt, C. F.: Oxygen Toxicity. Effects in Man of Oxygen Inhalation at 1 and 3,5 Atmospheres Upon Bloot Gas Transport, Cerebral Circulation and Cerebral Metabolism. J. appl. Physiol. 5, 471 (1953).

    PubMed  CAS  Google Scholar 

  24. Lambertsen, C. J., Ewing, J. H., Kough, R. H., Gould, R., Stroud, M. W.: Oxygen Toxicity. Arterial and Internal Jugular Blood Gas Composition in Man During Inhalation of Air, 100 % O2 and 2 % CO2 in O2 at 3,5 Atmospheres Ambient Pressure. J. appl. Physiol. 8, 255 (1955).

    PubMed  CAS  Google Scholar 

  25. Ledingham, McA., Mcdowall, D. G., Harper, A.M.: Cerebral Cortical Blood Flow Under Hyperbaric Conditions. Proc. III. Int. Conf. Hyperbaric Medicine, 243 (1966).

    Google Scholar 

  26. Sanders, A. P., Hall, I. H., Cavanaugh, P. J., Woodhall, B.: Effects of hyperbaric oxygenation on metabolism. I. ATP-concentration in rat brain, liver and kidney. Proc. Soc. exp. Biol. 121, 32–34 (1966).

    PubMed  CAS  Google Scholar 

  27. Shcherbakova, G. V.: Activity of glutamic decarboxylase and the content of γ-aminobutyric acid in rat brain at various levels of functional state caused by increased pressure of oxygen. Dokl. Akad. Nauk. SSSR 146, 1213 (1962) (zit. bei Haugaard [16]).

    CAS  Google Scholar 

  28. Thomas, J. J., Neptune, E. M., Sudduth, H. C.: Toxic Effects of Oxygen at High Pressure on the Metabolism of D-Glucose by Dispersion of Rat Brain. Biochem. J. 88, 31 (1963).

    PubMed  CAS  Google Scholar 

  29. Voronov, I. B.: Brain Structures and Origin of Convulsions Caused by High Oxygen Pressure (HOP). Int. J. Neuropharmacol. 3, 279 (1964).

    Article  PubMed  CAS  Google Scholar 

  30. van den Brenk, H. A. S., Jamieson, D.: Brain damage and paralysis in animals exposed to high pressure oxygen — Pharmacological and biochemical observations. Biochem. Pharmacol. 13, 165 (1964).

    Article  Google Scholar 

  31. Wood, J. D., Watson, W. J., Murray, G. W.: Correlation between Decreases in Brain γ-Aminobutyric Acid Levels and Susceptibility to Convulsions induced by Hyperbaric Oxygen. J. Neurochem. 16, 281 (1969).

    Article  PubMed  CAS  Google Scholar 

  32. Zirkle, L. G., Mengel, C. E., Horton, B. D., Duffy, E. J.: Studies of Oxygen Toxicity in the Central Nervous System. Aerospace Med. 36, 1027 (1965).

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Institut für Anästhesiologie, Universität Düsseldorf, Deutschland

    R. Purschke

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  1. R. Purschke
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  1. Institut für Anaesthesiologie, Universität Düsseldorf, Deutschland

    I. Podlesch (Prof., Dr.) (Prof., Dr.)

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Purschke, R. (1972). Wirkung hoher Sauerstoffdrucke auf das Zentralnervensystem. In: Podlesch, I. (eds) Sauerstoffüberdruckbehandlung. Anaesthesiology and Resuscitation Anaesthesiologie und Wiederbelebung Anesthésiologie et Réanimation, vol 64. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65398-8_6

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  • DOI: https://doi.org/10.1007/978-3-642-65398-8_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-05842-7

  • Online ISBN: 978-3-642-65398-8

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