Comparison between Sympathetic Activity in Human Skin- and Muscle Nerves and Accompanying Changes in Vascular Resistance
The results of numerous investigations of the peripheral circulation indicate a highly differentiated control of the sympathetic outflow to different vascular beds. Neurophysiological evidence for differentiated control of sympathetic outflow to arterial muscle- and skin vessels has now been given (HAGBARTH and VALLBO, 1968; WALLIN, DELIUS, HONGELL and HAGBARTH, 1971 a, b, d; WALLIN, HONGELL, HALLIN, TOREBJÖRK and HAGBARTH, 1971 c). Multi-unit sympathetic activity was recorded by microelectrodes inserted percutaneously into muscle- and skin nerves in alert, adult subjects together with measurements of intraarterial blood pressure and muscles- and skin blood flow in the extremities. The nervous signals were abolished by sympathetic ganglion bloking agents and by Lidocaine nerve blocks proximal to the recording site.
KeywordsNeral Nicotine Serotonin Histamine Epinephrine
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