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Current Topics in Microbiology and Immunology pp 1–38Cite as

Subacute Sclerosing Panencephalitis: A Review With 19 Figures

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 57))

Abstract

Subacute sclerosing panencephalitis is an inflammatory, progressive, slowly evolving disorder of the central nervous system, affecting children and young adults. The disease has been known for almost forty years and described during this period under various designations by many neuropathologists. Each name, being based on different neuropathological findings, suggested a distinct nosological entity. Thus Bodechtel and Guttmann (1931) described one case under the heading “diffuse encephalitis with sclerosing inflammation of the hemisphere white matter”, Dawson (1933, 1934) used the term “inclusion body encephalitis” Pette and Döring (1939) named the disease “pan-encephalomyelitis” and van Bogaert (1945) introduced the term “subacute sclerosing leukoencephalitis”. Only during the last twenty years have various investigators, after careful studies, come to the conclusion that these conditions were actually the same disease—one that can result in a broad variety of neuropathologic changes. At the present time the descriptive term “subacute sclerosing panencephalitis”, or SSPE, has been generally accepted as the designation for this disease.

This work was supported, in part, by Deutsche Forschungsgemeinschaft grants Me 270/4, Me 270/6, Mu 309/1 and Sonderforschungsbereich 33, Göttingen, „Nervensystem und biologische Information“ by the Stiftung Volkswagenwerk; by the Forschungsmittel des Landes Niedersachsen; by the Freudenberg Stiftung; and by U.S. Public Health Service Research Grant NS-06859 from the National Institute of Neurological Diseases and Stroke; by funds from the John A. Hartford Foundation.

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Author information

Author notes

  1. Michael Katz

    Present address: College of Physicians and Surgeons, Columbia University New York, NY, 10032, USA

Authors and Affiliations

  1. Department of Pediatrics, University of Göttingen, Germany

    Volker ter Meulen

  2. The Wistar Institute of Anatomy and Biology, Philadelphia, PA, USA

    Michael Katz

  3. Department of Neuropathology, University of Göttingen, Germany

    Dieter Müller

Authors
  1. Volker ter Meulen
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  2. Michael Katz
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  3. Dieter Müller
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Editor information

Editors and Affiliations

  1. Basle, Switzerland

    W. Arber  & N. K. Jerne  & 

  2. New Brunswick, Canada

    W. Braun

  3. Freiburg, Germany

    R. Haas

  4. Philadelphia, USA

    W. Henle , P. Koldovský  & H. Koprowski ,  & 

  5. Munich, Germany

    P. H. Hofschneider

  6. Copenhagen, Denmark

    O. Maaløe

  7. Gießen, Germany

    R. Rott

  8. Wilhelmshaven, Germany

    H. G. Schweiger

  9. Rehovot, Israel

    M. Sela

  10. Prague, Czech Republic

    L. Syruček

  11. Seattle, USA

    P. K. Vogt

  12. Würzburg, Germany

    E. Wecker

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© 1972 Springer-Verlag, Berlin · Heidelberg

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ter Meulen, V., Katz, M., Müller, D. (1972). Subacute Sclerosing Panencephalitis: A Review With 19 Figures. In: Arber, W., et al. Current Topics in Microbiology and Immunology. Current Topics in Microbiology and Immunology, vol 57. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65297-4_1

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  • DOI: https://doi.org/10.1007/978-3-642-65297-4_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-65299-8

  • Online ISBN: 978-3-642-65297-4

  • eBook Packages: Springer Book Archive

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