Physical Stability of the Microcirculation
Since 1951, BURTON and his colleagues have discussed physical equilibrium of vascular walls by utilizing the Law of Laplace and proposed the concept of critical closing pressure (1–4). These results have been quoted in several standard textbooks of physiology. The purpose of the present paper is to discuss critically the validity of applying the Laplacian equation to thick walled blood vessels on the basis of our general equation (5).
KeywordsLaplacian Equation Small Artery Blood Vessel Wall Active Tension Transmural Pressure
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