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Interpretation of Antimalarial Activity in Terms of Regression Analyses, Molecular Orbital Calculations, and Theory of DNA-Drug Binding

  • George E. Bass
  • Donna R. Hudson
  • Jane E. Parker
  • William P. Purcell
Part of the Progress in Molecular and Subcellular Biology book series (PMSB, volume 2)

Abstract

In 1965 a model to account for the antimalarial activity of chloroquine and its congeners was proposed by O’Brien and Hahn (O’Brien and Hahn, 1965) (see Fig. 1).

Keywords

Partition Coefficient Antimalarial Activity Molecular Orbital Calculation Quinoline Ring Substituent Constant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1971

Authors and Affiliations

  • George E. Bass
  • Donna R. Hudson
  • Jane E. Parker
  • William P. Purcell

There are no affiliations available

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