Abstract
In 1965 a model to account for the antimalarial activity of chloroquine and its congeners was proposed by O’Brien and Hahn (O’Brien and Hahn, 1965) (see Fig. 1).
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Bass, G.E., Hudson, D.R., Parker, J.E., Purcell, W.P. (1971). Interpretation of Antimalarial Activity in Terms of Regression Analyses, Molecular Orbital Calculations, and Theory of DNA-Drug Binding. In: Hahn, F.E. (eds) Proceedings of the Research Symposium on Complexes of Biologically Active Substances with Nucleic Acids and Their Modes of Action. Progress in Molecular and Subcellular Biology, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65141-0_12
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