Skip to main content

Abstract

The immune response, the activation of lymphoid cells by antigen, has been studied in various in vitro systems. For example, specific antigen stimulates lymphoid cells from sensitized animals to incorporate thymidine and to produce non-antibody substances (lymphokines) which will affect the behaviour of other cells (Wolstencroft et al., this symposium). I shall discuss the ability of lymphoid cells to elaborate antibody in vitro, and describe the induction of haemolysin synthesis during the primary immune response of cultured mouse spleen cells to foreign erythrocytes.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Mishell, R.I., Dutton, R.W.: J. exp. Med.126, 423 (1967).

    Article  PubMed  CAS  Google Scholar 

  2. Jerne, N.K., Nordin, A. A., Henry, C., in: Cell bound antibodies. Eds.:B. Amos and H. Koprowski. Philadelphia 1963, p. 109.

    Google Scholar 

  3. Mosier, D. E.: Science 158, 1575 (1967).

    Article  Google Scholar 

  4. Hartman, K.-U., Dutton, R. W., McCarthy, Margareth, M., Mishell, R. I.: Cellular Immunology, in press.

    Google Scholar 

  5. Hoffmann, M.: Immunology 18, 791 (1970).

    PubMed  CAS  Google Scholar 

  6. Mishell, R. I., Dutton, R. W., Raidt,D. J.: Cellular Immunology, in press.

    Google Scholar 

  7. Hashill, J. S.: J. exp. Med. 130, 877 (1969).

    Article  Google Scholar 

  8. Schimpl A., Wecker,E.: Personal comm.

    Google Scholar 

  9. Clamann, H. N., Chaperon, E. A., Triplett, R. F.: Proc. Soc. exp. Biol. (N.Y.) 122, 167 (1966).

    Google Scholar 

  10. Miller. J. F. A. P., Mitchell, G. F.: J. exp. Med. 128, 801 (1968).

    Article  PubMed  CAS  Google Scholar 

  11. Hirst, J. A., Dutton, R. W.: Cellular Immunology, in press.

    Google Scholar 

  12. Munro, A., Hunter. P.: Nature 255, 277 (1970).

    Article  Google Scholar 

  13. Schimpl, A., Wecker, E.: Nature 226, 1258 (1970).

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1971 Springer Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

Hartmann, KU. (1971). In vitro Studies of Cellular Co-Operation during Immune Induction. In: Dumonde, D.C. (eds) The Role of Lymphocytes and Macrophages in the Immunological Response. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65133-5_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-65133-5_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-65135-9

  • Online ISBN: 978-3-642-65133-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics