Abstract
The characterization of cell surface receptors on mononuclear cells may give important information on their immunological functions. We and others reported on distinct receptor sites for IgG and the third component of complement present on monocytes and macrophages [3, 4, 6, 7]. Recently immunoglobulin determinants on certain lymphocytes have been demonstrated by several investigators [2, 10, 14]. In order to further assess receptor sites on lymphocytes, the reactivity of normal cells, those separated by density gradients and of cells from patients with chronic lymphocytic leukaemia were tested for the presence of membrane receptors for antigen-antibody-complement complexes. A certain correlation between this sub-population of lymphocytes and those with immunoglobulin determinants on their membrane was observed.
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References
Bianco,Bianco C., Patrick,R., Nussenzweig,V: J. exp. Med. (in press).
Coombs, R. R. A.,Franks, D.: Progr. Allergy13, 174 (1969).
Huber, H.,Fudenberg, H. H.: Int. Arch. Allergy34, 18 (1968).
Huber, H., Polley, M. J., Linscott, W. D., Fudenberg, H. H.,Müller-Eberhard, H. J.: Science 162, 1281 (1968).
Johannson, B., Klein, E.: Clin. exp. Immun. 6, 421 (1970).
Lay, H. W., Nussenzweig, V.: J. exp. Med.128, 991 (1968).
Lobuglio, A. F.,Cotran, R. S.,Jandl, J. H.: Science 158,1582 (1967).
Miller, J. F. A. P.,Mitchell, G. F.: J. exp. Med. 128, 801 (1968).
Raff, M. C.: Nature 224, 378 (1969).
Raff, M. C. Sternberg, M., Taylor, R. B.: Nature 225, 553 (1970).
Raidt, D. J., Mishell, R. I., Dutton, R. W.: J. exp. Med. 128, 681 (1968).
Rajewsky, K., in: Current Problems in Immunology. Eds.: O. Westphal, H. E. Bock, and E. Grundmann. Berlin-Heidelberg-New York: Springer 1969, p. 91.
Rieber, H. P., Riethmüller, G.: Paper read at the first session of the Society for Immunology, Freiburg/Brsg., Oct. 16–18 (1969).
Sell, S., Asofsky, R.: Prog Allergy 12, 86 (1968).
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Huber, H., Michlmayr, G., Huber, C., Asamer, H., Douglas, S.D. (1971). Inhomogeneity of Peripheral Lymphocytes — Complement Receptor Sites on a Portion of Human Lymphocytes. In: Dumonde, D.C. (eds) The Role of Lymphocytes and Macrophages in the Immunological Response. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65133-5_15
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DOI: https://doi.org/10.1007/978-3-642-65133-5_15
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