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Effect of Ethanol on Steroid Metabolism

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Abstract

The liver plays an important role in the reductive metabolism of steroids. We assumed that the increase of the NADH/NAD+ ratio that is observed during ethanol oxidation would influence this metabolism. A series of studies has therefore been started which aims at the elucidation of steroid reactions that are affected by ethanol metabolism. The investigations are carried out along two main lines: 1. analysis of steroid redox couples in blood and urine before and after ethanol administration and 2. analysis of the incorporation of deuterium into steroids during the metabolism of [1-2H2]-ethanol.

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© 1971 Springer-Verlag Berlin · Heidelberg

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Cronholm, T., Makino, I., Sjövall, J. (1971). Effect of Ethanol on Steroid Metabolism. In: Martini, G.A., Bode, C. (eds) Metabolic Changes Induced by Alcohol. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65131-1_23

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  • DOI: https://doi.org/10.1007/978-3-642-65131-1_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-05296-8

  • Online ISBN: 978-3-642-65131-1

  • eBook Packages: Springer Book Archive

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