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Zellkinetische Untersuchungen zur Klärung der Ursache periodischer Schwankungen des Neutrophilenspiegels im Blut bei einem Fall von zyklischer Neutropenie

Examination of the Cellular Kinetics to Explain the Periodic Fluctuations in the Neutrophil Count in a Case of Cyclic Neutropenia

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Frontiers of Nuclear Medicine/Aktuelle Nuklearmedizin

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Summary

The kinetics of granulopoiesis and neutrophils was studied in a case of cyclic neutropenia using labeling techniques (3HTDR, 3H-DFP) combined with serial quantitative evaluations of the granulopoietic cells. It was demonstrated that the oscillation of the neutrophil count was caused by rhythmic fluctuations of the neutrophil production rate due to periodic changes in the proliferation activity of granulopoiesis. The results could be interpreted as indicating pathological regulation of granulopoiesis.

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Author information

Authors and Affiliations

  1. Abteilung für Nuklearmedizin, der Medizinischen Universitätsklinik Freiburg i. Br., Germany

    G. Meuret

  2. Abteilung für klinische Physiologie, Zentrum für klinische Grundlagenforschung der Universität Ulm, Germany

    G. Meuret

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  1. G. Meuret
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Editors and Affiliations

  1. Kantonsspital, CH-8006, Zurich, Switzerland

    Wolfgang Horst (Direktor der Universitätsklinik und Poliklinik für Nuklearmedizin und Radiotherapie) (Direktor der Universitätsklinik und Poliklinik für Nuklearmedizin und Radiotherapie)

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© 1971 Springer-Verlag, Berlin · Heidelberg

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Meuret, G. (1971). Zellkinetische Untersuchungen zur Klärung der Ursache periodischer Schwankungen des Neutrophilenspiegels im Blut bei einem Fall von zyklischer Neutropenie. In: Horst, W. (eds) Frontiers of Nuclear Medicine/Aktuelle Nuklearmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65092-5_8

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  • DOI: https://doi.org/10.1007/978-3-642-65092-5_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-65094-9

  • Online ISBN: 978-3-642-65092-5

  • eBook Packages: Springer Book Archive

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