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Autonomic Nervous System

  • Chapter
Modern Inhalation Anesthetics

Abstract

In considering drug effects on the autonomic nervous system, acknowledgement must be made, at the outset, that changes in autonomic nervous activity produced by pharmacological means are not necessarily a result of the direct action of the agent on the receptors of this essentially efferent system. Anesthetic agents probably alter autonomic function by effects on afferent receptors or on some select sites in the central nervous system. However, drug effects on the final common pathway of autonomic outflow will have precedence in determining organ and organ system pharmacodynamics. It is not the intention of the author to present an encyclopedic approach to the subject material of this chapter, but rather to exploit concepts that are explicit or implied in the data presently available from the experimental pharmacology of anesthetic drugs. Rather than consider each agent as a pharmacological entity, the presentation will be in the mode of systems analyses and dissections of these will be carried out only so far as they complement the whole and expose the problems and voids therein.

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  1. Robert W. Gardier
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  1. Biochemical Research Laboratory, The Dow Chemical Company, Midland, MI, 48640, USA

    Maynard B. Chenoweth

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Gardier, R.W. (1972). Autonomic Nervous System. In: Chenoweth, M.B. (eds) Modern Inhalation Anesthetics. Handbuch der experimentellen Pharmakologie/Handbook of Experimental Pharmacology, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65055-0_7

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