Abstract
The interest in veterinary anesthesia has increased considerably, with greater focus on anesthesia as an important part of animal management and care. The approach and attitude has shifted from anesthesia as being only a necessary part of a surgical procedure to a greater overall awareness of its importance in the management of the animal from the preoperative through to the postoperative period. Along with the growing awareness of the practicing veterinarian in the greater use of newer anesthetic agents and techniques, has been an increased interest on the part of the experimental surgeon and research worker in better anesthetic methods. There has also been a greater concern for the impact of drugs and anesthetic agents on experimental results. Unfortunately, herein lies one of the greatest deficiencies of our knowledge of general anesthesia. The rapid development of the field of biomedical engineering has given the research scientist the means for the development of more sophisticated chronic models. This has placed a greater responsibility on the researcher for the use of better anesthetic techniques and a greater awareness on pre and postoperative care.
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References
Adamson, D. W., Green, A. F.: New series of analgesics. Nature 165, 122 (1950).
Adriani, J., Yarberry, O. H., Jr.: Preanesthetic medication. Old and new concepts. Arch. Surg. 79, 976 (1959).
Ayre, P.: The T-piece technique. Brit. J. Anaesthesia 28, 520 (1956).
Bahga, H. S., Link, R. P.: Cardiovascular effects of two phenothiazines: fluphenazine and trifluoperazine. Am. J. Yet. Research 27, 81 (1966).
Baratta, A., Brandslater, B., Muallem, M., Seraphim, C.: Rebreathing in a double T-piece system. Brit. J. Anaesthesia 4, 47 (1969).
Bennett, R. R.: The clinical use of 2-(ethylamino)-2-(2-thienyl) cyclohexanone HC1 (CI 634) as an anesthetic for the cat. Am. J. Yet. Research 30, 1469 (1969).
Booth, N. H., Rankin, A. D.: Evaluation of meperidine hydrochloride in the cat. Yet. Med. 49, 249 (1954).
Boulos, B. M., Davis, L. E.: Hazard of simultaneous administration of phenothiazine and piperazine. New Engl. J. Med. 280, 1245 (1969).
Bourgeois-Gavardin, M., Nowill, W. K., Margolis, G., Stephen, C. R.: Chlorpromazine, a laboratory and clinical investigation. Anesthesiology 16, 829 (1955).
Boutelle, J. L., Rich, S. T.: An anesthetic chamber for prolonged immobilization of mice during tumor transplantation and radiation procedures. Lab. An. Care 19, 666 (1969).
Bree, M. M., Feller, I., Corssen, G.: Safety and tolerance of repeated anesthesia with CI 581 (ketamine) in monkeys. Anesthesia Current Researches & Analgesia 46, 596 (1967).
Burn, J. H., Epstein, H. G., Fergan, G. A., Paton, W. D. M., Burns, T. H. S., Mushin, W. W., Organe, G. S. W., Robertson, J. D.: Fluothane: A report to the Medical Research Council by the Committee on Non-explosive Anesthetic Agents. Brit. Med. J. 2, 479 (1957).
Burstein, C. L., LoPinto, F. J., Newman, W.: Electrocardiographic studies during endotracheal intubation; effects during usual routine technics. Anesthesiology 11, 224 (1950).
Calderwood, H., Klide, A., Cohn, B., Soma, L.: The effects of tilitamine (CI 634) in the cat. Am. J. Yet. Research (in press).
Calderwood, H., Klide, A., Soma, L.: Department of Clinical Studies, Section of Anesthesia, University of Pennsylvania Veterinary School, Philadelphia, Pennsylvania. Unpublished data, 1970.
Carey, F. M., Sanford, J.: A method of assessing the effect of drugs on the performance in the horse. Proc. Brit. Eq. Assoc. 52, (1965).
Carlson, W. D.: A clinical evaluation of meperidine hydrochloride as a preanesthetic agent in the cat. Vet. Med. 50, 229 (1955).
Chen, G., Ensor, C. R.: 2-(ethylamino)-2-(2-thienyl) cyclohexanone HC1 (CI 634): A taming, incapacitating, and anesthetic agent for the cat. Am. J. Yet. Research 29, 863 (1968).
Chen, G., Ensor, C. R., Russell, D., Bohner, B.: The pharmacology of l-(l-phencylcyclohexyl) piperidine HC1. J. Pharmacol. Exptl. Therap. 127, 241 (1959).
Clarke, K. W., Hall, L. W.: Xylazine — a new sedative for horses and cattle. Vet. Record 85, 512 (1969).
Clifford, D. H., Soma, L. R.: Chapter 22, Feline Medicine and Surgery, 1st Ed. Santa Barbara, Calif.: American Veterinary Publications, Inc. 1964.
Collard, J. A.: Unusual reaction to chlorpromazine hydrochloride in a bich. Australian Vet. J. 34, 90 (1958).
Collette, W. L., Meriwether, W. F.: Some changes in the peripheral blood of dogs after administration of certain tranquillizers and narcotics. Vet. Med./Small Animal Clinician 60, 1223 (1965).
Collins, R. J.: Potency of dihydromorphinone, methadone, and codeine compared to morphine in self-maintained addict rats. Federation Proc. 22, 248 (1963).
Conney, A. H.: Pharmacological implications of microsomal enzyme induction. Pharmacol. Revs 19, 317 (1967).
Corssen, G., Domino, E. F.: Dissociative anesthesia: further pharmacologic studies and first clinical experience with phencyclidine derivative CI-581. Current Researches Anesthesia & Analgesia 45, 29 (1966).
Dobkin, A. B.: Potentiation of thiopental anaesthesia with Tigan, Panectyl, Benadryl, Gravol. Marzine, Histadyl, Librium, Haloperidol (R 1625). Canad. Anaesth. Soc. J. 8, 265 (1961).
Domino, E. F.: Neurobiology of phencyclidine (Sernyl), a drug with an unusual spectrum of pharmacological activity. Intern. Rev. Neurobiol. 6, 303 (1964).
Domino, E. F., Chodoff, P., Corssen, G.: Pharmacologic effects of CI-581, a new dissociative anesthetic in man. Clin. Pharmacol. Therap. 6, 279 (1965).
Dripps, R. D., Eckenhoff, J. E., Vandam, L. D.: Introduction to anesthesia, 2nd ed. Philadelphia, Pa.: Saunders, W. B. 1961.
Dundee, J. W.: Thiopentone and other thiobarbiturates. London: E. and S. Livingstone, LTD 1956.
Editorial. Anesthesiology 25, 3 (1964).
Epling, G. P., Rankin, A. D.: Metopon analgesia in the dog. Am. J. Vet. Research 15, 338 (1954).
Feldberg, W., Paton, W. D. M.: Release of histamine by morphine alkaloids. J. Physiol. (London) 111, 19 (1950).
Flyger, V.: Handling wild mammals with new tranquillizer. Trans. Twenty-Sixth North Am. Wildlife and Natural Resourses Conf., 230, 1961.
Fowler, W. S.: Lung function studies, respiratory dead space. Am. J. Physiol. 154, 405 (1948).
Friedman, J. J.: Effect of Nembutal on circulating and tissue blood volumes and hematocrits of intact and splenectomezed mice. Am. J. Physiol. 197, 399 (1959).
Gabel, A. A., Hamlin, R., Smith, C. R.: Effects of promazine and chloral hydrate on the cardiovascular system of the horse. Am. J. Vet. Research 25, 1151 (1964).
Gabel, A. A., Koestner, A.: The effects of intracarotid artery injection of drugs in animals. J. Am. Vet. Med. Assoc. 142, 1397 (1963).
Godeaux, J., Innesen, M.: Investigations into atropine metabolism in animal organism. Acta Pharmacol. Toxicol. 5, 95 (1949).
Goodman, L. S., Gilman, A.: The pharmacological basis of therapeutics, 3rd ed. New York: Macmillan Co. 1965.
Graham-Jones, O.: (1) Restraint and anaesthesia of some captive wild mammals. Vet. Record 76, 1216 (1964).
Graham-Jones, O. (2) Discussion of Smits, G. M.: Some experiments and experiences with neuroleptic and hypnotic drugs on ungulates with special regard to Librium. Proceed, of Fifth Internat. Symp. on Disease of Zoo Animals. Royal Neth. Vet. Assoc. Tij. Dierg. 89, 195 (1964).
Graham-Jones, O., Tranquillizer and paralytic drugs. An international survey of animal restraint techniques. Intern. Zoo Yearbook 2, 300 (1960).
Hall, L. W.: Wright’s veterinary anesthesia and analgesia, 6th ed. Baltimore, Md.: William and Wilkings Co. 1966.
Hall, L. W., Stevenson, D. F.: Effects of ataractic drugs on the blood pressure and heart rate of dogs. Nature 187, 696 (1960).
Harrison, G. A.: Ayre’s T-piece: A review of its modifications. Brit. J. Anaesthesia 36, 118 (1964).
Harthoorn, A. M.: Application of pharmacological and physiological principles in restraint of wild animals. Wildlife Monograph 14, 1 (1965).
Harthoorn, A. M., (1) On the use of phencyclidine for narcosis in the larger animals. Yet. Record 74, 410 (1962).
Harthoorn, A. M., (2) Producing “twilight sleep” in large wild mammals. J. Am. Vet. M.d. Assoc. 141, 1473 (1962).
Harthoorn, A. M., Textbook of veterinary anesthesiology (Soma, L. R., Ed.), Chapter 29. The capture and restraint of wild animals. Baltimore, Md.: Williams and Wilkins Co. 1971.
Heavner, J. E.: Morphine for postsurgical use in cats. J. Am. Vet. Med. Assoc. 156, 1018 (1970).
Hoe, C. M., Wilkinson, J. S.: A diluting effect of chlorpromazine hydrochloride on the circulating blood of dogs. Vet. Record 69, 734 (1957).
Hutchinson, B. R.: Changes in pulse rate and blood pressure after extubation. Brit. J. Anaesthesia 86, 661 (1964).
Hutchinson, B. R., Electrocardiographic changes in children following extubation. Med. J. Australia 1, 151 (1956).
Johnstone, M.: Pethidine and general anesthesia. Brit. Med. J. 2, 943 (1951).
Kaelber, W. W., Toynt, R. J.: Tremor production in cats given chlorpromazine. Proc. Soc. Exptl. Biol. Med. 92, 399 (1956).
Kain, L. M., Nunn, J. F.: Fresh gas economics of the Magill Circuit. Anesthesiology 29, 964 (1968).
Killip, T.: Sinus nerve stimulation in the chloralose anesthetized cat: Effect on blood pressure, heart rate, muscle blood flow and vascular resistance. Acta Physiol. Scand. 57, 437 (1963).
King, B. D., Harris, L. C., Jr., Greifenstein, F. E., Elder, J. D., Jr., Dripps, R. D.: Reflex circulatory responses to direct laryngoscopy and tracheal intubation performed during general anesthesia. Anesthesiology 12, 556 (1961).
Kroll, W. R.: Experience with Sernylan in zoo animals. Intern. Zoo Yearbook 4, 131 (1962).
Kruegar, H., Eddy, N. B., Sumwalt, M.: The pharmacology of the opium alkaloids. Supplement 165. Pub. Health Rep., U.S. Government Printing Office, Washington, D.C., Part I, 1941, Part I I, 1943.
Lewis, R. N., Swerdlow, M.: Hazards of endotracheal anesthesia. Brit. J. Anaesthesia 36, 504 (1964).
Lowenstein, E., Mallowell, P., Levine, H., Daggett, W. M., Austen, W., Lavor, M. B.: Cardiovascular response to large doses of intravenous morphine in man. New Engl. J. Med. 281, 1389 (1969).
Mapelson, W. W.: The elimination of rebreathing in various semiclosed anesthetic systems. Brit. J. Anaesthesia 26, 323 (1954).
Martin, J. E., Beck, J. D.: Some effects of chlorpromazine in horses. Am. J. Vet. Research. 17, 678 (1958).
Matorras, A. A., Felipe, M. A. N.: Selection of indications on the use of CI-581 and observations on 198 cases. Progress in Anaesthesiology, Proceedings of the Fourth World Congress of Anaesthesiologists, p. 1000, London 1968. Excerpta Med. Foundation, Amsterdam 1970.
Medd, R. K., Heywood, R.: A technic for intubation and repeated short-duration anesthesia in the rat. Lab. An. 4, 75 (1970).
Negus, V.: Biology of respiration. Edinburgh, London: E. and S. Livingstone, LTD 1965.
Nytch, T. F.: Clinical observations on the preanesthetic use of oxymorphine and its antagonist N-allyl-noroxymorphane, in dogs. J. Am. Vet. Med. Assoc. 145, 127 (1964).
Orahovats, P. D., Lehman, E. G., Chapin, E. W.: Pharmacology of Ethyl-l-(4-aminophen- ethyl)-4-phenylisonipecotate, anileridine, a new potent synthetic analgesic. J. Pharmacol. Exptl. Therap. 119, 26 (1957).
Orr, D., Jones, I.: Anesthesia for laryngoscopy. Current Researches Anesthesia & Analgesia 23, 194 (1968).
Owen, L. N.: Thirambutene-thiopentone anesthesia for hysterectomy in pyometra of the bitch. Vet. Record 67, 580 (1955).
Quentin, J. R. L., Siry, J. R.: Tranquillizers in veterinary medicine. Ag. Vet. Chem. 3, 136 (1962).
Ratcliffe, H. L.: Diazepam (Tranimal) as a tranquillizer for zoo animals. Report Penrose Res. Lab. Zool. Soc. of Phila., 10, 1962.
Redgate, J. D., Gellhorn, E.: The tonic effect of the posterior hypothalamus on blood pressure and pulse rate disclosed by the action of intra-hypothalamically injected drugs. Arch, intern, pharmacodynamic 105, 193 (1956).
Remmen, E., Cohen, S., Ditman, K. S., Frantz, J. R.: Psychochemotherapy, the physicians manual, Chap. 4. Los Angeles, Calif.: Western Medical Publications 1962.
Rex, M. A. E.: Stimulation of larynospasms in the cat by volatile anesthetics. Brit. J. Aneasthesia 38, 569 (1966).
Rex, M. A. E., The laryngeal reflex. New Zealand Vet. J. 15, 222 (1967).
Reynolds, A. K., Randall, L. O.: Morphine and allied drugs. Canada: University of Toronto Press 1957.
Robbins, B. H.: Studies on cyclopropane IX. The effect of premedication with demerol upon the heart rate, rhythm and blood pressure in dogs under cyclopropane anesthesia. J. Pharmacol. Exptl Therap. 85, 198 (1945).
Rubin, A. Winston, J.: The role of the vestibular apparatus in the production of nausea and vomiting following the administration of morphine to man. J. Clin. Invest. 29, 1261 (1950).
Sagner, G., Hoffmeister, F., Kroneberg, G.: Pharmacological basis of a new drug for analgesia, sedation and relaxation in veterinary medicine, Bayer Va 1470 or “Rompun”. Deut. tierärztl. Wochschr. 75, 565 (1968).
Seal, U. S., Erickson, A. W.: Immobilization of Carnivora and other mammals with phencyclidine and promazine. Federation Proc. 28 (1969).
Shemano, I., Wendel, H.: Effects of meperidine hydrochloride and morphine sulfate on the lung capacity of intact dogs. J. Pharmacol. Exptl Therap. 149, 379 (1965).
Simmons, M. L., Smith, L. H.: An anesthetic unit for small laboratory animals. J. Appl. Physiol. 25, 324 (1968).
Smith, T. C., Stephen, G. W., Zeiger, L., Wollman, H.: Effects of premedicant drugs on respiration and gas exchange in man. Anesthesiology 28, 883 (1967).
Smits, G. M.: Some experiments and experiences with neuroleptic and hypnotic drugs on ungulates with special regard to librium. Proc. of Fifth Internat. Symp. on Diseases of Zoo Animals. Royal Neth. Vet. Assoc., Ti; Dierg. 89, 195 (1964).
Soma, L. R.: (Ed.): (1) Textbook of veterinary anesthesia Baltimore, Md.: Williams and Wilkins Co. 1971.
Soma, L. R.: (Ed.): (2) Textbook of veterinary anesthesia, Chap. 21, Equipment and techniques for inhalation agents. Baltimore, Md.: Williams and Wilkins Co. 1971.
Soma, L. R., Shields, D. R.: Neuroleptanalgesia produced by fentanyl and droperidol. J. Am. Vet. Med. Assoc. 145, 897 (1964).
Stoliker, H. E.: The physiological and pharmacological effects of Sernylan: a review. Experimental Animal Anesthesiology, pp. 148–184. U.S. School of Aerospace Medicine, Aerospace Medical Division (AFSC), Brooks Air Force Base, San Antionio, Texas, July, 1965.
Strobel, G. E., Wollman, H.: Pharmacology of anesthetic agents. Federation Proc. 28, 4 (1969).
Sugioka, K., Boniface, K. J., Davis, D. A.: The influence of meperidine on myocardial contractility in the intact dog. Anesthesiology 18, 623 (1957).
Sykes, M. K.: Non-rebreathing valves. Brit. J. Anaesthesia 31, 450 (1959).
Tavernor, W. D.: An assessment of promazine hydrochloride as a sedative in the dog. Vet. Record 74, 779 (1962).
Telivuo, L. J., Vaisanen, R.: Clinical experience with a phencyclidine derivative CI-581. Progress in Anesthesiology Proceedings of the Fourth World Congress of Anesthesiologists. London, 1968. Excerpta Med. Foundation, Amsterdam 1970.
Tevik, A., Sharpe, J., Nelson, A. W., Berkely, W. E., Lumb, W. V.: Effect of nitrogen in a closed circle system with low oxygen flows for equine anesthesia. J. Am. Vet. Med. Assoc. 154, 166 (1969).
V.A. Laboratory Guide: Comparative anesthesia in laboratory animals. Federation Proc. 28. 4 (1969).
Vasko, J. S., Henney, R. P., Browley, R. K., Oldham, H. N., Morrow, A. G.: Effects of morphine on ventricular function and myocardial contractile force. J. Physiol. (London) 210, 329 (1966).
Wang, S. C., Barison, H. L.: A new concept of organization of the central emetic mechanism. Gastroenterology 22, 1 (1952).
Westhues, M., Fritsch, R.: Die Narkose der Tiere, Band I. Lokalanästhesie, Band II, Allgemeine Narkose. Berlin: Paul Parey 1961.
Westhues, M., Fritsch, R., Animal anaesthesia: general, 1st ed. Philadelphia, Pennsylvania: J. B. Lippincott Co. 1965.
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Soma, L.R., Calderwood, H.W. (1972). Comparative Aspects of Anesthesia in Animals. In: Chenoweth, M.B. (eds) Modern Inhalation Anesthetics. Handbuch der experimentellen Pharmakologie/Handbook of Experimental Pharmacology, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65055-0_20
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