Abstract
Because of the complexity and difficulty of access to the brain many of the pioneer studies on cerebral metabolism and anesthesia were done on excised tissue in vitro. Authoritative surveys of the results have been made by Quastel (1965) and by Hunter and Lowry (1956). For a broad view the classic discussion by Butler (1950) is still pertinent.
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Fink, B.R. (1972). Effects of Anesthetics on Metabolism of Brain. In: Chenoweth, M.B. (eds) Modern Inhalation Anesthetics. Handbuch der experimentellen Pharmakologie/Handbook of Experimental Pharmacology, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65055-0_18
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