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Hypothalamic LH-Releasing Hormone: Chemistry, Physiology and Effect in Humans

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Mammalian Reproduction

Abstract

There is now good evidence that the secretion of LH and FSH from the anterior pituitary gland is controlled principally by the central nervous system and a feedback system, involving sex steroids [1, 2]. The hypothalamus stimulates the secretion of follicle stimulating hormone (FSH), luteinizing hormone (LH) and other pituitary hormones by releasing regulatory substances into portal blood flowing from the median eminence region into the pars distalis [3, 4]. Table 1 lists the known hypothalamic hormones and the new nomenclature we have proposed for them [4]. In this report we shall be concerned only with LH-releasing hormone (LH-RH) and FSH-releasing hormone (FSH-RH). Their function is to augment the secretion of LH and FSH.

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Author information

Authors and Affiliations

  1. Endocrine and Polypeptide Laboratories and Endocrinology Section of the Medical Service, Veterans Administration Hospital, USA

    A. V. Schally, A. Arimura, A. J. Kastin, J. J. Reeves, C. Y. Bowers & Y. Baba

  2. Department of Medicine, Tulane University School of Medicine, New Orleans, La., USA

    A. V. Schally, A. Arimura, A. J. Kastin, J. J. Reeves, C. Y. Bowers & Y. Baba

  3. Scientific Divisions, Abbott Laboratories, North Chicago, Illinois, USA

    W. F. White

Authors
  1. A. V. Schally
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  2. A. Arimura
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  3. A. J. Kastin
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  4. J. J. Reeves
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  5. C. Y. Bowers
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  6. Y. Baba
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Editors and Affiliations

  1. Pharmaforschung Schering AG, Müllerstraße 170–172, D-1000, Berlin 65, Germany

    Heinz Gibian

  2. Universitätsfrauenklinik, D-5300, Bonn-Venusberg, Germany

    Ernst Jürgen Plotz

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Schally, A.V. et al. (1970). Hypothalamic LH-Releasing Hormone: Chemistry, Physiology and Effect in Humans. In: Gibian, H., Plotz, E.J. (eds) Mammalian Reproduction. Colloquium der Gesellschaft für Biologische Chemie in 9.–11. April 1970 in Mosbach/Baden, vol 21. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-64993-6_4

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  • DOI: https://doi.org/10.1007/978-3-642-64993-6_4

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  • Print ISBN: 978-3-642-64995-0

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