Abstract
In addition to problems of immune tolerance and the technique of transplantation one must pose the question of how a transplanted pancreas will function under conditions of daily life. In order to investigate this problem we initiated a trial in an animal model. Two questions were of particular interest:
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1.
Would pancreas transplantation in diabetic recipient animals normalize fasting and stimulated hyperglycemia, the probable cause of vascular damage in diabetics?
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2.
What are the basal values for insulin, glucagon, and glucose and the secretion kinetics of insulin following various stimulation tests.
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© 1985 Springer-Verlag Berlin, Heidelberg
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Meister, R., Paul, K. (1985). Investigations of Glucose Tolerance Following Pancreatic Transplantation in Rats with Streptozotocin-Induced Diabetes. In: Thiede, A., Deltz, E., Engemann, R., Hamelmann, H. (eds) Microsurgical Models in Rats for Transplantation Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61657-0_31
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DOI: https://doi.org/10.1007/978-3-642-61657-0_31
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-64899-1
Online ISBN: 978-3-642-61657-0
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