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Combined Pancreas and Kidney Transplatation in the Rat

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Microsurgical Models in Rats for Transplantation Research
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Abstract

Most centres that have applied pancreatic transplantation for the treatment of Type-I insulin-dependent diabetes mellitus have performed simultaneous renal grafting (Dubernard et al.1981; Baumgartner et al. 1983; McMaster 1983). The Combined procedure currently carries a higher success rate than pancreas transplantation when performed alone (Sutherland 1983). Although experimental models do exist in large mammals for simultaneous pancreaticorenal transplantation (Severyn et al.1982), no satisfactory microsurgical model has been described. We report a microsurgical model for combined pancreaticorenal transplantation. This permits the use of highly inbred rat strain with their concomitant advantages.

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© 1985 Springer-Verlag Berlin, Heidelberg

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Nolan, M.S., Lindsey, N.J., Ingram, N.P., Herold, A., Salter, D.N., Fox, M. (1985). Combined Pancreas and Kidney Transplatation in the Rat. In: Thiede, A., Deltz, E., Engemann, R., Hamelmann, H. (eds) Microsurgical Models in Rats for Transplantation Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61657-0_26

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  • DOI: https://doi.org/10.1007/978-3-642-61657-0_26

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64899-1

  • Online ISBN: 978-3-642-61657-0

  • eBook Packages: Springer Book Archive

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