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Characteristics and Applications of Pediocin(S) of Pediococcus Acidilactici: Pediocin PA-1/AcH.

  • Conference paper
Lactic Acid Bacteria

Part of the book series: NATO ASI Series ((ASIH,volume 98))

Summary

Many food-grade lactic acid bacteria produce a group of peptides, classified as bacteriocins, that are bactericidal to many gram-producer bacteria. On the basis of the presence of a modified amino acid, lanthionine, they are grouped as lantibiotics and nonlanthionine bacteriocins. Due to the stability of the antibacterial action at high heat and in the environment of many foods, there is an interest in using bacteriocins of lactic acid bacteria as food biopreservatives.

However, many of the bacteriocins of lactic acid bacteria are bactericidal only to a few strains of gram-positive bacteria. Among those with antibacterial action against different spoilage and pathogenic gram-positive bacteria, the lantibiotic nisin, and nonlanthionine bacteriocins, pediocin PA-1 and pediocin AcH of Pediococcus acidilactici strains have been thoroughly studied. As pediocin PA-1 and pediocin AcH are identical peptides, a name pediocin PA-l/AcH has been used in this article.

Nisin has been studied for over 50 years and at present, approved for used in some foods. It has been discussed in other chapters. In this chapter the results of studies on various aspects of pediocin PA-l/AcH are discussed. These include: antibacterial spectrum, mode of antibacterial action, bactericidal effect against sublethally injured bacteria, factors influencing bactericidal effect, safety and antigenic property, immunity and resistance, characteristics of the peptide, genetic control in production, optimum production and purification, and effectiveness in food systems.

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Authors and Affiliations

  1. Animal Science Department, University of Wyoming, Box 3684, Laramie, WY, 82071, USA

    Bibek Ray

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  1. Department of Food Engineering, Middle East Technical University, 06531, Ankara, Turkey

    T. Faruk Bozoğlu

  2. Department of Animal Science, University of Wyoming, 82070, Laramie, WY, USA

    Bibek Ray

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Ray, B. (1996). Characteristics and Applications of Pediocin(S) of Pediococcus Acidilactici: Pediocin PA-1/AcH.. In: Faruk Bozoğlu, T., Ray, B. (eds) Lactic Acid Bacteria. NATO ASI Series, vol 98. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61462-0_8

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