Abstract
Despite an abundance of studies on the mechanisms regulating renin release in mammals, studies in nonmammalian species are rather scant. The initial part of this chapter will therefore be devoted to reviewing the present state of knowledge about the regulation of renin release in mammals. The details of the mechanism are extensively reviewed by Davis and Freeman (1976), Keeton and Campbell (1981), Gibbons et al. (1984), Fray et al. (1987) and Hackenthal et al. (1990). Increasing evidence shows that the kidney secretes both active and inactive renin, and the activation of inactive renin signiIicantly contributes to changes in plasma renin activity in humans (Sealey and Laragh 1975), dogs (James and Hall 1974), and pigs (Bailie et al. 1979; Okamura and Inagami 1984). This activation process, however, has not been studied sufficiently in nonmammalian species.
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© 1996 Springer-Verlag Berlin Heidelberg
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Kobayashi, H., Takei, Y. (1996). Regulation of Renin Release. In: The Renin-Angiotensin System. Zoophysiology, vol 35. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61164-3_5
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DOI: https://doi.org/10.1007/978-3-642-61164-3_5
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-64725-3
Online ISBN: 978-3-642-61164-3
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